3,869 research outputs found

    Dynamic Density Response of Trapped Interacting Quantum Gases

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    An expression for the dynamic density response function has been obtained for an interacting quantum gas in Random Phase Approximation (RPA) including first order self and exchange contribution. It involves the single particle wave functions and eigen values. The expression simplifies when diagonal elements are considered. The diagonal elements of the imaginary part of Fourier transformed response function is relevant in the measurement of Bragg scattering cross-section and in several other applications.Comment: 2 pages, 0 figure, conferenc

    AdS (In)stability: Lessons From The Scalar Field

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    We argued in arXiv:1408.0624 that the quartic scalar field in AdS has features that could be instructive for answering the gravitational stability question of AdS. Indeed, the conserved charges identified there have recently been observed in the full gravity theory as well. In this paper, we continue our investigation of the scalar field in AdS and provide evidence that in the Two-Time Formalism (TTF), even for initial conditions that are far from quasi-periodicity, the energy in the higher modes at late times is exponentially suppressed in the mode number. Based on this and some related observations, we argue that there is no thermalization in the scalar TTF model within time-scales that go as ∼1/ϵ2\sim 1/\epsilon^2, where ϵ\epsilon measures the initial amplitude (with only low-lying modes excited). It is tempting to speculate that the result holds also for AdS collapse.Comment: 10 pages, 4 figure

    Smooth Non-negative Matrix Factorization framework for visually appealing storyboard

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    We present a novel framework to consequently identify occasions from search log information and produce storyboards where the occasions are orchestrated sequentially. We picked picture look log as the asset for occasion mining, as search logs can straightforwardly mirror individuals' inclinations. To find occasions from log information, we present a Smooth Nonnegative Matrix Factorization structure (SNMF) which consolidates the data of question semantics, transient relationships, search logs and time congruity. Also, we consider the time factor a significant component since various occasions will create in various time inclinations. Also, to give a media-rich and outwardly engaging storyboard, every occasion is related with a lot of delegate photographs orchestrated along a course of events. These applicable photographs are naturally chosen from picture query items by investigating picture content features

    PREPARATION, CHARACTERISATION AND EVALUATION OF ROPINIROLE HYDROCHLORIDE LOADED CONTROLLED RELEASE MICROSPHERES USING SOLVENT EVAPORATION TECHNIQUE

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    Objective: The major objective of the research work was to design, characterise and evaluate controlled release microspheres of ropinirole hydrochloride by using non-aqueous solvent evaporation technique to facilitate the delivery of the drug at a predetermined rate for a specific period of time.Methods: Ropinirole hydrochloride microspheres were prepared by using different low-density polymers such as eudragit RL 100, eudragit RS 100 and ethylcellulose either alone or in combination with the help of non-aqueous solvent evaporation technique. All the formulated microparticles were subjected to various evaluation parameters such as particle size analysis, micrometric properties, drug entrapment efficiency, percentage drug loading, percentage yield and in vitro drug release study. The compatibility of the drug and polymers was confirmed by physical compatibility study, fourier transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC) and x-ray diffraction study (XRD). The formation of the most optimized batch of the microsphere (F12) was confirmed by scanning electron microscopy (SEM), DSC, FTIR, and XRD. In vitro drug release study and in vitro drug release kinetics study of the formulated microspheres were also carried out.Results: Drug-polymer compatibility studies performed with the help of FTIR and DSC indicated that there were no interactions. Results revealed that non-aqueous solvent evaporation technique was a suitable technique for the preparation of microspheres as most of the formulations were discrete, free-flowing and spherical in shape with a good yield of 55.67% to 80.09%, percentage drug loading of 35.52% to 94.50% and percentage drug entrapment efficiency of 36.24% to 95.07%. Different drug-polymer ratios, as well as the combination of polymers, played a significant role in the variation of over-all characteristics of formulations. Based on the data of various evaluation parameters such as particle size analysis, percentage drug loading, percentage drug entrapment, percentage yield, rheological studies and in vitro drug release characteristics, formulation F12 was found to fulfil the criteria of ideal controlled release drug delivery system. F12 showed controlled release till the 14th hour (97.99%) and its in vitro release kinetics was best explained by zero-order kinetics and followed Korsemeyer-Pappas model (Non-Fickian mechanism). SEM of F12 revealed the formation of spherical structures. The FTIR study of F12 confirmed the stable nature of ropinirole in the drug-loaded microspheres. DSC and XRD patterns showed that ropinirole hydrochloride was dispersed at the molecular level in the polymer matrix.Conclusion: The controlled release microparticles were successfully prepared and from this study, it was concluded that the developed microspheres of ropinirole hydrochloride can be used for controlled drug release to improve the bioavailability and patient compliance and to maintain a constant drug level in the blood target tissue by releasing the drug in zero order pattern

    COMPARATIVE STUDY OF YIELDS AND TOTAL PHENOLIC AND FLAVONOID CONTENTS OF EXTRACTS OF DIFFERENT EXTRACTION METHODS OF CLITORIA TERNATEA (FABACEAE)

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    Objective: The present study aims at comparison of extraction yields, total phenolic and flavonoid contents of methanolic extracts from various methods of extraction of leaves of Clitoria ternatea (Fabaceae). Methods: Dried leaves were extracted by Maceration, Soxhlation and Microwave Assisted Extraction (MAE) methods and the percentage yields were calculated. Further total phenolic and flavonoid contents were determined for the extracts obtained as above. Each of the experiments were performed in triplicate. Results: The methanolic extract of MAE was found to show the highest yield (12.22 % w/w) compared to the other methods performed. Total phenolic and flavonoid contents were also determined in the highest amount in MAE (248.29±0.29 mg GAE/gm and 191.64±1.45 mg QE/gm) than soxhlation and maceration. Conclusion: Microwave assisted extraction method possessed highest extraction yield and total phenolic and total flavonoid contents than the other two extraction methods which makes it economical and effective not only for its increased yield but also for better quality of extract, consuming less time and solvent. Further studies on this may be beneficial to establish this method for regular extraction and isolation of phytoconstituents

    Importance of Technological Innovation for SME Growth: Evidence from India

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    This paper probes the drivers, dimensions, achievements, and outcomes of technological innovations carried out by SMEs in the auto components, electronics, and machine tool sectors of Bangalore in India. Further, it ascertains the growth rates of innovative SMEs vis-à-vis non-innovative SMEs in terms of sales turnover, employment, and investment. Thereafter, it probes the relationship between innovation and growth of SMEs by (i) estimating a correlation between innovation sales and sales growth, (ii) calculating innovation sales for high, medium, and low growth innovative SMEs and doing a aggregate one-way ANOVA, and (iii) ascertaining the influence of innovation sales, along with investment growth and employment growth on gross value-added growth by means of multiple regression analysis. The paper brings out substantial evidence to argue that innovations of SMEs contributed to their growth.Technological innovations, sales growth, auto components, electronics, machine tools, Bangalore
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