Evolution of Thrombosis of the Vein of Galen in Sickle Cell Disease

PubMedID: 8505485[No abstract available

EVOLUTION OF THROMBOSIS OF THE VEIN OF GALEN IN SICKLE-CELL DISEASE

WOS: A1993LB79000017PubMed ID: 8505485

Light and electron microscopic, and immunohistochemical analysis of deposits in the proximal ends of ventriculoperitoneal shunt catheters

The ventriculoperitoneal shunt is accepted as the simplest and most effective treatment for hydrocephalus. The major problem with these devices is obstruction of the proximal end of the tubing. In this study, we examined deposits in the proximal ends of Codman shunts from 20 of our patients whose catheter failed. Light microscopic examination revealed that the deposited material contained fibrin, other proteinaceous material, erythrocytes, lymphocytes, macrophages, eosinophils, leukocytes, giant cells, and evidence of neovascularization. Electron microscopy confirmed the presence of fibrin, other proteinaceous material, many phagocytic cells, giant cells, and bacteria within the cytoplasm of these two types of cells. Immunohistochemically, the deposited material stained intensely for IgA, moderately for IgG, and weakly for IgM. This report discusses on ventriculoperitoneal shunt failure and the types of deposits that accumulate at the proximal end of the catheter, and reviews the relevant literature. The authors conclude that such deposits do cause shunt failure

Multiple anterolateral cervical meningoceles associated with neurofibromatosis

PubMedID: 10547012In neurosurgical practice, the term 'spinal t meningocele' is generally used to describe a congenital spinal malformation including protrusion of the spinal meninx from the congenitally dysraphic vertebrae. Although non- dysraphic meningocele is very rare, it is usually associated with neurofibromatosis or Marfan's syndrome in the literature. Thoracic and/or lumbar spinal levels are the most common localization. Anterolateral localization of meningocele is very rare in the cervical region. Operative treatment is indicated if the lesion is symptomatic. Detailed radiological assessment of the meningocele is necessary since it may be associated with neuroma in the sac. If the neuroma is found in the meningocele, an anterior surgical approach should be considered for the treatment of both of the lesions

Intracranial arterial aneurysm complicating Behçet's disease

PubMedID: 8738367Behçet's disease, a rare condition in central Europe but more common in Turkey where it was originally described, is characterized clinically by the presence of a diagnostic triad of oral and genital aphthous ulcers, meningitis, and relapsing iridocyclitis. Vascularlesions including arterial and venous occlusions, arterial aneurysms and varices are one of the common complications of Behçet's disease occur most commonly in the abdominal aorta, femoral arteries and pulmonary arteries. There have been only four reports of aneurysms of cerebral arteries in the literature. The authors describe a patient with Behçet's disease who suffered secondary subarachnoid hemorrhage due to a ruptured aneurysm of the anterior communicating artery 3 years after the initial diagnosis. This case report draws further attention to this rare entity in patients with Behçet's disease

Effect of trapidil in ischemia/reperfusion injury of peripheral nerves

BAGDATOGLU, CELAL/0000-0002-4237-9288; SURUCU, HUSEYIN SELCUK/0000-0002-9244-4236WOS: 000176611700046PubMed: 12182420OBJECTIVE: Ischemia plays an important role in the development of pathological changes in nerve tissue, and restoration of blood flow results in injury (ischemia/ reperfusion [I/R] injury) mediated by toxic oxygen free radicals. Trapidil is currently used as a coronary artery vasodilating agent and is also used for the prevention of ischemic symptoms of cerebral vasospasm. The purpose of this study was to determine the effects of trapidil on I/R injury and the ischemic tolerance of rat peripheral nerves. METHODS: Preischemia or prereperfusion administration of trapidil (8 mg/kg) was evaluated in the rat sciatic nerve I/R injury model. Nerve tissue samples from the I/R injury site were assayed for malondialdehyde (MDA), nitrites, and nitrates, as markers of I/R injury, and pathological changes were evaluated by electron microscopy. RESULTS: I/R resulted in an increase in MDA levels, which remained elevated for 2 weeks in control nerves. Rats that received trapidil before ischemia exhibited decreased MDA levels, and rats that received trapidil after the standard 3 hours of ischemia demonstrated increased tolerance to reperfusion, as reflected in significantly decreased MDA levels. Nitrite and nitrate levels in trapidil-treated rats were significantly higher than those in control animals. Histological evaluations of the sciatic nerve segments demonstrated that preischemia and postischemia trapidil treatments had a sparing effect against the myelin damage and axonal edema that are consistently noted in untreated ischemic reperfused nerves. CONCLUSION: The results confirm that pretreatment with trapidil before the ischemic insult or before reperfusion provides marked protection against I/R injury in peripheral nerves

Lipomas of the corpus callosum a report of four cases

Lipomas of the corpus callosum are rare congenital conditions. These lesions are often asymptomatic but may present as epilepsy, hemiplegia, dementia or headache. Computerized tomography and magnetic resonance imaging make the diagnosis of lipomas feasible at any site of the intracranial space, because of very low density attenuation values on computerized tomography and the short T1 and T2 on magnetic resonance. A direct surgical approach is very rarely necessary in these lesions. Four cases with lipoma of the corpus callosum diagnosed by computed tomography are presented and the literature is reviewed. Basic diagnostic considerations and therapeutic options are discussed

UNILATERAL HYDROCEPHALUS RESULTING FROM OCCLUSION OF FORAMEN OF MONRO - A NEW PROCEDURE IN THE TREATMENT - STEREOTAXIC FENESTRATION OF THE SEPTUM-PELLUCIDUM

WOS: A1993KU28300007PubMed ID: 8351622Obstruction at the foramen of Monro resulting in unilateral hydrocephalus is an uncommon entity that may be caused by a wide range of lesions including tumors, vascular malformations, and inflammatory conditions. A case of unilateral hydrocephalus secondary to congenital atresia of the foramen of Monro treated with stereotactic fenestration of the septum pellucidum is presented

TRAUMATIC GIANT ANEURYSM OF THE INTRACAVERNOUS INTERNAL CAROTID-ARTERY CAUSING FATAL EPISTAXIS - CASE-REPORT

WOS: A1994NG22200018PubMed ID: 8158721A patient with a giant intracavernous carotid aneurysm usually has symptoms and signs of a space-occupying lesion, producing one of a variety of types of cavernous sinus syndromes. Epistaxis is an unusual feature in these patients. A patient who noted the onset of repeated arterial epistaxis 2 years after a severe head injury was found to have a traumatic aneurysm of the cavernous portion of internal carotid artery. After angiography, he suddenly developed profuse, pulsatile, arterial epistaxis and had a cardiopulmonary arrest. This case and a review of previously reported cases emphasize the importance of early cerebral angiography in patients with posttraumatic recurrent epistaxis

An unusual complication of the ventriculo-peritoneal shunt: Migration of the distal end into the scrotum through the inguinal canal

[No abstract available