78 research outputs found

    The State in Retreat? Why has India Experienced Such Half?hearted ‘Liberalisation’ in the 1980s?

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    Summary Summary The promise of economic liberalisation in the 1985 Budget and the rapid retreat from it that ensued, are described and then explained in relation to long?term trends of India's political economy. The very half?hearted liberalisation that took place can be understood as the outcome of fiscal problems of long?standing; and these in turn are the result of the compromise of power between propertied classes (Bardhan's model) and the weakness of the state as an organisation. The Rajiv regime did attempt to reassert the autonomy of high politics, but the attempt was short?lived because of the lack of political capacity to confront propertied groups — amongst which there are strong interests in the maintenance of regulation. Resumen Resumen ¿El estado en retirada? ¿Por qué India experimentó una ‘liberalización’ tan tenue en la décade de 1980? Se describe la liberalización económica anunciada en el presupuesto de 1985 de la India y su rápido abandono, explicándose ésto por las tendencias de largo plazo de su economía política. La liberalización extremadamente suave que tuvo lugar, puede entenderse como resultado de problemas fiscales de larga data. Esto a su vez, es consecuencia del compromiso de poder entre las clases propietarias (mode 10 Bardhan) y la debilidad de la organización estatal. El régimen Rajiv intentó reasegurar la autonomía de la alta política, pero el intento fue de corta duración por la insuficiente capacidad para enfrentar a los grupos proprietarios, entre los cuales hay fuertes intereses para mantener la regulación

    Mouse Chromosome 11

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/46996/1/335_2004_Article_BF00648429.pd

    Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

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    Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

    Endovascular therapy in the distal neurovascular territory: results of a large prospective registry.

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    There is a paucity of data regarding mechanical thrombectomy (MT) in distal arterial occlusions (DAO). We aim to evaluate the safety and efficacy of MT in patients with DAO and compare their outcomes with proximal arterial occlusion (PAO) strokes. The Trevo Registry was a prospective open-label MT registry including 2008 patients from 76 sites across 12 countries. Patients were categorized into: PAO: intracranial ICA, and MCA-M1; and DAO: MCA-M2, MCA-M3, ACA, and PCA. Baseline and outcome variables were compared across the PAO vs DAO patients with pre-morbid mRS 0-2. Among 407 DAOs including 350 (86.0%) M2, 25 (6.1%) M3, 10 (2.5%) ACA, and 22 (5.4%) PCA occlusions, there were 376 DAO with pre-morbid mRS 0-2 which were compared with 1268 PAO patients. The median baseline NIHSS score was lower in DAO (13 [8-18] vs 16 [12-20], P<0.001). There were no differences in terms of age, sex, IV-tPA use, co-morbidities, or time to treatment across DAO vs PAO. The rates of post-procedure reperfusion, symptomatic intracranial hemorrhage (sICH), and 90-mortality were comparable between both groups. DAO showed significantly higher rates of 90-day mRS 0-2 (68.3% vs 56.5%, P<0.001). After adjustment for potential confounders, the level of arterial occlusion was not associated with the chances of excellent outcome (DAO for 90-day mRS 0-1: OR; 1.18, 95% CI [0.90 to 1.54], P=0.225), successful reperfusion or SICH. However, DAO patients were more likely to be functionally independent (mRS 0-2: OR; 1.45, 95% CI [1,09 to 1.92], P=0.01) or dead (OR; 1.54, 95% CI [1.06 to 2.27], P=0.02) at 90 days. Endovascular therapy in DAO appears to result in a comparable safety and technical success profile as in PAO. The potential benefits of DAO thrombectomy should be investigated in future randomized trials
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