5,736 research outputs found
PAMELA's cosmic positron from decaying LSP in SO(10) SUSY GUT
We propose two viable scenarios explaining the recent observations on cosmic
positron excess. In both scenarios, the present relic density in the Universe
is assumed to be still supported by thermally produced WIMP or LSP (\chi). One
of the scenarios is based on two dark matter (DM) components (\chi,X) scenario,
and the other is on SO(10) SUSY GUT. In the two DM components scenario,
extremely small amount of non-thermally produced meta-stable DM component
[O(10^{-10}) < n_X /n_\chi] explains the cosmic positron excess. In the SO(10)
model, extremely small R-parity violation for LSP decay to e^\pm is naturally
achieved with a non-zero VEV of the superpartner of one right-handed neutrino
(\tilde{\nu}^c) and a global symmetry.Comment: 6 pages, Talks presented in PASCOS, SUSY, and COSMO/CosPA in 201
On magnetic leaf-wise intersections
In this article we introduce the notion of a magnetic leaf-wise intersection
point which is a generalization of the leaf-wise intersection point with
magnetic effects. We also prove the existence of magnetic leaf-wise
intersection points under certain topological assumptions.Comment: 43 page
Radion Dynamics and Phenomenology in the Linear Dilaton Model
We investigate the properties of the radion in the 5D linear dilaton model
arising from Little String Theory. A Goldberger-Wise type mechanism is used to
stabilise a large interbrane distance, with the dilaton now playing the role of
the stabilising field. We consider the coupled fluctuations of the metric and
dilaton fields and identify the physical scalar modes of the system. The
wavefunctions and masses of the radion and Kaluza-Klein modes are calculated,
giving a radion mass of order the curvature scale. As a result of the direct
coupling between the dilaton and Standard Model fields, the radion couples to
the SM Lagrangian, in addition to the trace of the energy-momentum tensor. The
effect of these additional interaction terms on the radion decay modes is
investigated, with a notable increase in the branching fraction to photons. We
also consider the effects of a non-minimal Higgs coupling to gravity, which
introduces a mixing between the Higgs and radion modes. Finally, we calculate
the production cross section of the radion at the LHC and use the current Higgs
searches to place constraints on the parameter space.Comment: 28 pages, 7 figures; v2: error in radion-gauge boson Feynman rules
corrected, version published in JHE
Key distillation from quantum channels using two-way communication protocols
We provide a general formalism to characterize the cryptographic properties
of quantum channels in the realistic scenario where the two honest parties
employ prepare and measure protocols and the known two-way communication
reconciliation techniques. We obtain a necessary and sufficient condition to
distill a secret key using this type of schemes for Pauli qubit channels and
generalized Pauli channels in higher dimension. Our results can be applied to
standard protocols such as BB84 or six-state, giving a critical error rate of
20% and 27.6%, respectively. We explore several possibilities to enlarge these
bounds, without any improvement. These results suggest that there may exist
weakly entangling channels useless for key distribution using prepare and
measure schemes.Comment: 21 page
DNA end resection by Dna2–Sgs1–RPA and its stimulation by Top3–Rmi1 and Mre11–Rad50–Xrs2
The repair of DNA double-strand breaks (DSBs) by homologous recombination requires processing of broken ends. For repair to start, the DSB must first be resected to generate a 3′-single-stranded DNA (ssDNA) overhang, which becomes a substrate for the DNA strand exchange protein, Rad51 (ref. 1). Genetic studies have implicated a multitude of proteins in the process, including helicases, nucleases and topoisomerases. Here we biochemically reconstitute elements of the resection process and reveal that it requires the nuclease Dna2, the RecQ-family helicase Sgs1 and the ssDNA-binding protein replication protein-A (RPA). We establish that Dna2, Sgs1 and RPA constitute a minimal protein complex capable of DNA resection in vitro. Sgs1 helicase unwinds the DNA to produce an intermediate that is digested by Dna2, and RPA stimulates DNA unwinding by Sgs1 in a species-specific manner. Interestingly, RPA is also required both to direct Dna2 nucleolytic activity to the 5′-terminated strand of the DNA break and to inhibit 3′ to 5′ degradation by Dna2, actions that generate and protect the 3′-ssDNA overhang, respectively. In addition to this core machinery, we establish that both the topoisomerase 3 (Top3) and Rmi1 complex and the Mre11–Rad50–Xrs2 complex (MRX) have important roles as stimulatory components. Stimulation of end resection by the Top3–Rmi1 heterodimer and the MRX proteins is by complex formation with Sgs1 (refs 5, 6), which unexpectedly stimulates DNA unwinding. We suggest that Top3–Rmi1 and MRX are important for recruitment of the Sgs1–Dna2 complex to DSBs. Our experiments provide a mechanistic framework for understanding the initial steps of recombinational DNA repair in eukaryotes
Graduate HRD Programs in South Korea
The Problem To address national issues associated with societal development, many countries are recognizing the need to educate individuals who will lead developmental initiatives. While many previous studies have been conducted to examine how and what content of human resource development (HRD) has been taught in Western countries, similar research efforts have been rarely conducted in Asian countries such as South Korea. The lack of comparative study creates a research gap in understanding how HRD programs have been designed and implemented in different countries.Yeshttps://us.sagepub.com/en-us/nam/manuscript-submission-guideline
Four-Dimensional Effective Supergravity and Soft Terms in M-Theory
We provide a simple macroscopic analysis of the four-dimensional effective
supergravity of the Ho\v{r}ava-Witten M-theory which is expanded in powers of
and where ,
and denote the eleven-dimensional gravitational coupling, the
Calabi-Yau volume and the eleventh length respectively. Possible higher order
terms in the K\"ahler potential are identified and matched with the heterotic
string corrections. In the context of this M-theory expansion, we analyze the
soft supersymmetry-breaking terms under the assumption that supersymmetry is
spontaneously broken by the auxiliary components of the bulk moduli
superfields. It is examined how the pattern of soft terms changes when one
moves from the weakly coupled heterotic string limit to the M-theory limit.Comment: Latex, 23 pages, 3 figures. References are added and the discussion
of the M-theory expansion parameters is enlarge
Impact of early disease factors on metabolic syndrome in systemic lupus erythematosus: data from an international inception cohort
BACKGROUND: The metabolic syndrome (MetS) may contribute to the increased cardiovascular risk in systemic lupus erythematosus (SLE). We examined the association between MetS and disease activity, disease phenotype and corticosteroid exposure over time in patients with SLE. METHODS: Recently diagnosed (\u3c15 \u3emonths) patients with SLE from 30 centres across 11 countries were enrolled into the Systemic Lupus International Collaborating Clinics (SLICC) Inception Cohort from 2000 onwards. Baseline and annual assessments recorded clinical, laboratory and therapeutic data. A longitudinal analysis of factors associated with MetS in the first 2 years of follow-up was performed using random effects logistic regression. RESULTS: We studied 1150 patients with a mean (SD) age of 34.9 (13.6) years and disease duration at enrolment of 24.2 (18.0) weeks. In those with complete data, MetS prevalence was 38.2% at enrolment, 34.8% at year 1 and 35.4% at year 2. In a multivariable random effects model that included data from all visits, prior MetS status, baseline renal disease, SLICC Damage Index \u3e1, higher disease activity, increasing age and Hispanic or Black African race/ethnicity were independently associated with MetS over the first 2 years of follow-up in the cohort. CONCLUSIONS: MetS is a persistent phenotype in a significant proportion of patients with SLE. Renal lupus, active inflammatory disease and damage are SLE-related factors that drive MetS development while antimalarial agents appear to be protective from early in the disease course
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