A Longitudinal Study Investigating the Brain Spurts Theory

This longitudinal study investigates brain growth periodization, also known as the brain spurts theory. The theory calls for maximum brain growth between the ages 2-4 years, 6-8 years, 10-12 years, and 14-16 years. For several decades researchers have observed fluctuations in the rate of growth for various areas of student achievement. These fluctuations occur in an extreme form from ages 8 - 14. The brain spurts theory asserts that there is also variation during this period in the rate of brain cell development. This researcher utilized a random sample of 50 students in a western New York school district where data was available for their scaled achievement scores on the Stanford Achievement Test battery. The sampled students come from both rural and suburban areas. They were all in the same grade level at the time of the study. The basic purpose of this study was to see if there was an explanatory fit between the fluctuations asserted by the brain spurts theory and the fluctuations observed in achievement scores for this sample. An ancillary question that was investigated was whether or not a significant difference in mean performance existed between males and females on each of the sub-tests on the Stanford Achievement Test battery. Since this was a pilot descriptive investigation, the 90% confidence level was chosen as the level at which to test the significance of the difference between two independent group means. The decision to include this ancillary question also lead to stratifying the random sample of 25 males and 25 females. Male/female comparisons were made using a 2-sample t-test. The scaled scores of the Math Application, Math Computation, Reading Comprehension, and Vocabulary portions of the Stanford Achievement Tests were used. A data base was created and all of the statistics utilized in this study were computed using the computer statistical package GB-Stat by Dynamic Microsystems, Inc. Graphs on growth for ages 8 - 14 were completed. The coefficients of determination were also computed. Inconclusive evidence was found to either support or oppose the above stated theory. Inconsistencies were found in the growth patterns of the four areas tested. Two basically matched the growth pattern of the brain spurts theory and two did not. Possibilities for the inconsistencies are discussed in the conclusion. It was found that the best coefficient of determination value for the scores achieved at 14 years was at an age level which was at the same point in the growth pattern of the brain spurts theory

Inventory of Property owned by David B. Westcott

Inventory of property owned by David B. Westcotthttps://scholarsjunction.msstate.edu/lantern-mcpc/1199/thumbnail.jp

Inventory of Enslaved Peopled owned by David B. Westcott

Inventory of enslaved people owned by David B. Westcotthttps://scholarsjunction.msstate.edu/lantern-mcpc/1196/thumbnail.jp

Inventory of Enslaved People owned by David B. Westcott

Inventory of enslaved people owned by David B. Westcotthttps://scholarsjunction.msstate.edu/lantern-mcpc/1201/thumbnail.jp

Inventory of Property owned by David B. Westcott

Inventory of property owned by David B. Westcotthttps://scholarsjunction.msstate.edu/lantern-mcpc/1198/thumbnail.jp

Inventory of Property owned by David B. Westcott

Inventory of property owned by David B. Westcotthttps://scholarsjunction.msstate.edu/lantern-mcpc/1197/thumbnail.jp

Inventory of Enslaved People owned by David B. Westcott

Inventory of enslaved people owned by David B. Westcotthttps://scholarsjunction.msstate.edu/lantern-mcpc/1200/thumbnail.jp

Investigation of the fundamental constants stability based on the reactor Oklo burn-up analysis

The burn-up for SC56-1472 sample of the natural Oklo reactor zone 3 was calculated using the modern Monte Carlo codes. We reconstructed the neutron spectrum in the core by means of the isotope ratios: $^{147}$Sm/$^{148}$Sm and $^{176}$Lu/$^{175}$Lu. These ratios unambiguously determine the spectrum index and core temperature. The effective neutron absorption cross section of $^{149}$Sm calculated using this spectrum was compared with experimental one. The disagreement between these two values allows to limit a possible shift of the low laying resonance of $^{149}$Sm even more . Then, these limits were converted to the limits for the change of the fine structure constant $\alpha$. We found that for the rate of $\alpha$ change the inequality $|\delta \dot{\alpha}/\alpha| \le 5\cdot 10^{-18}$ is fulfilled, which is of the next higher order than our previous limit.Comment: 16 pages, 7 figure

Efficacy of Tacrolimus in Uveitis, and the Usefulness of Serum Tacrolimus Levels in Predicting Disease Control. Results from a Single Large Center

Aims: To evaluate the efficacy of tacrolimus in patients with noninfectious uveitis, as well as the usefulness of serum tacrolimus concentration measurements in predicting disease control. Methods: A retrospective review was carried out on 71 eligible patients from a single specialist uveitis center for minimum 1-year follow-up. Analysis was carried out on disease activity, visual acuity, and trough serum tacrolimus concentrations (STC). Results: At 1-year follow-up, disease control was achieved in 49 patients (69.0%), this was significantly more likely in patients with trough STC levels above 5 ng/mL (88% vs 53%, p = .002). There was a significant reduction in oral prednisolone (dose ≥7.5 mg, 86% vs 54%, p < .0001). Tacrolimus was discontinued in 12 patients (17%) due to side effects. Discussion: In this study cohort, oral tacrolimus was effective and well tolerated in the treatment of noninfectious uveitis. Trough STC between 5 ng/mL and 10 ng/ml was associated with better disease control at 1-year follow-up

Phenotypic Switching of Adipose Tissue Macrophages With Obesity Is Generated by Spatiotemporal Differences in Macrophage Subtypes

OBJECTIVE—To establish the mechanism of the phenotypic switch of adipose tissue macrophages (ATMs) from an alternatively activated (M2a) to a classically activated (M1) phenotype with obesity