New electron source concept for single-shot sub-100 fs electron diffraction in the 100 keV range

We present a method for producing sub-100 fs electron bunches that are suitable for single-shot ultrafast electron diffraction experiments in the 100 keV energy range. A combination of analytical results and state-of-the-art numerical simulations show that it is possible to create 100 keV, 0.1 pC, 20 fs electron bunches with a spotsize smaller than 500 micron and a transverse coherence length of 3 nm, using established technologies in a table-top set-up. The system operates in the space-charge dominated regime to produce energy-correlated bunches that are recompressed by established radio-frequency techniques. With this approach we overcome the Coulomb expansion of the bunch, providing an entirely new ultrafast electron diffraction source concept

Decay of the supersonic turbulent wakes from micro-ramps

The wakes resulting from micro-ramps immersed in a supersonic turbulent boundary layer at Ma = 2.0 are investigated by means of particle image velocimetry. Two micro-ramps are investigated with height of 60% and 80% of the undisturbed boundary layer, respectively. The measurement domain is placed at the symmetry plane of the ramp and encompasses the range from 10 to 32 ramp heights downstream of the ramp. The decay of the flow field properties is evaluated in terms of time-averaged and root-mean-square (RMS) statistics. In the time-averaged flow field, the recovery from the imparted momentum deficit and the decay of upwash motion are analyzed. The RMS fluctuations of the velocity components exhibit strong anisotropy at the most upstream location and develop into a more isotropic regime downstream. The self-similarity properties of velocity components and fluctuation components along wall-normal direction are followed. The investigation of the unsteady large scale motion is carried out by means of snapshot analysis and by a statistical approach based on the spatial auto-correlation function. The Kelvin-Helmholtz (K-H) instability at the upper shear layer is observed to develop further with the onset of vortex pairing. The average distance between vortices is statistically estimated using the spatial auto-correlation. A marked transition with the wavelength increase is observed across the pairing regime. The K-H instability, initially observed only at the upper shear layer also begins to appear in the lower shear layer as soon as the wake is elevated sufficiently off the wall. The auto-correlation statistics confirm the coherence of counter-rotating vortices from the upper and lower sides, indicating the formation of vortex rings downstream of the pairing region

Numerical and experimental investigations of the supersonic microramp wake

The flow past a microramp immersed in a supersonic turbulent boundary layer is studied by means of numerical simulations with the implicit large-eddy simulation technique and experiments conducted with tomographic particle image velocimetry. The experimental data are mostly used to verify the validity of the numerical results by ample comparisons on the time-averaged velocity, turbulent statistics, and vortex intensity. Although some discrepancies are observed on the intensity of the upwash motion generated by the streamwise vortex pair, the rates of the recovery of momentum deficit and the decay of streamwise vortex pair intensity are found in good agreement. The instantaneous flow organization is inspected, making use of the flow realizations available from implicit large-eddy simulation. The flow behind the microramp exhibits significant large-scale unsteady fluctuations. Notably, the quasi-conical shear layer enclosing the wake is strongly undulated under the action of Kelvin–Helmholtz (K–H) vortices. The resulted vortices induce localized high-speed arches in the outer region and a deceleration within the wake associated with ejection of low-momentum fluid. Because of the presence of the K–H vortex, the streamwise vortex filaments exhibit downward and outward motions. The further evolution of vortical structures within the wake features the development of K–H vortices from arch shape to full ring in the far wake, under the effects of the streamwise vortices, which induce an inward motion of the vortex legs and eventually connect the vortex at the bottom

Depressive Symptoms and Amygdala Volume in Elderly with Cerebral Small Vessel Disease: The RUN DMC Study

Introduction. Late onset depressive symptoms (LODSs) frequently occur in elderly with cerebral small vessel disease (SVD). SVD cannot fully explain LODS; a contributing factor could be amygdala volume. We investigated the relation between amygdala volume and LODS, independent of SVD in 503 participants with symptomatic cerebral SVD. Methods. Patients underwent FLAIR and T1 scanning. Depressive symptoms were assessed with structured questionnaires; amygdala and WML were manually segmented. The relation between amygdala volume and LODS/EODS was investigated and adjusted for age, sex, intracranial volume, and SVD. Results. Patients with LODS had a significantly lower left amygdala volume than those without (P = 0.02), independent of SVD. Each decrease of total amygdala volume (by mL) was related to an increased risk of LODS (OR = 1.77; 95% CI 1.02–3.08; P = 0.04). Conclusion. Lower left amygdala volume is associated with LODS, independent of SVD. This may suggest differential mechanisms, in which individuals with a small amygdala might be vulnerable to develop LODS

A Tutorial on the Proper Orthogonal Decomposition

This tutorial introduces the Proper Orthogonal Decomposition (POD) to engineering students and researchers interested in its use in fluid dynamics and aerodynamics. The objectives are firstly to give an intuitive feel for the method and secondly to provide example MATLAB codes of common POD algorithms. The discussion is limited to the finite-dimensional case and only requires knowledge of basic statistics and matrix algebra. The POD is first introduced with a two-dimensional example in order to illustrate the different projections that take place in the decomposition. The n-dimensional case is then developed using experimental data obtained in a turbulent separation-bubble flow and numerical results from simulations of a cylinder wake flow