Long Span DNA Paired-End-Tag (DNA-PET) Sequencing Strategy for the Interrogation of Genomic Structural Mutations and Fusion-Point-Guided Reconstruction of Amplicons

10.1371/journal.pone.0046152PLoS ONE79

Simplicity in Visual Representation: A Semiotic Approach

Simplicity, as an ideal in the design of visual representations, has not received systematic attention. High-level guidelines are too general, and low-level guidelines too ad hoc, too numerous, and too often incompatible, to serve in a particular design situation. This paper reviews notions of visual simplicity in the literature within the analytical framework provided by Charles Morris' communication model, specifically, his trichotomy of communication levels—the syntactic, the semantic, and the pragmatic. Simplicity is ultimate ly shown to entail the adjudication of incompatibilities both within, and between, levels.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/68281/2/10.1177_105065198700100103.pd

Mahatma Gandhi and the Prisoner’s Dilemma: Strategic Civil Disobedience and Great Britain’s Great Loss of Empire in India

This paper examines the relationship between statutory monopoly and collective action as a multi-person assurance game culminating in an end to British Empire in India. In a simple theoretical model, it is demonstrated whether or not a collective good enjoys (or is perceived to enjoy) pure jointness of production and why the evolutionary stable strategy of non-violence was supposed to work on the principle that the coordinated reaction of a ethnically differentiated religious crowd to a conflict between two parties (of colonizer and colonized) over confiscatory salt taxation would significantly affect its course. Following Mancur Olson (1965) and Dennis Chong (1991), a model of strategic civil disobedience is created which is used to demonstrate how collective action can be used to produce an all-or-nothing public good to achieve economic and political independence

Filtrage bidimensionnel de spectrogrammes sonar

Nous considérons qu'un spectrogramme temps-fréquence d'un signal issu d'une antenne acoustique peut être assimilé à une image numérique de dimension finie (NxM) dans laquelle : - les lignes représentent les spectres engendrés par le bruit parasite et par le signal utile, ce dernier étant caractérisé par des raies fréquentielles ; - chaque colonne est composée de points statistiquement indépendants sauf si une raie fréquentielle (signal) est présente. Pour améliorer l'aspect visuel de ce type d'image et donc son interprétation, on y applique un filtrage homomorphique (filtrage bidimensionnel interposé entre une transformation logarithmique et une transformation exponentielle). Des résultats expérimentaux validés par le tracé de courbes COR permettront de comparer cette méthode à des techniques classiques telles que le "moyennage glissant" et la normalisation