7,971 research outputs found

    ZnO nanocrystalline thin films: a correlation of microstructural, optoelectronic properties

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    The compositional, structural, microstructural, dc electrical conductivity and optical properties of undoped zinc oxide films prepared by the sol-gel process using a spin-coating technique were investigated. The ZnO films were obtained by 5 cycle spin-coated and dried zinc oxide films followed by annealing in air at 600 ° C. The films deposited on the platinum coated silicon substrate were crystallized in a hexagonal wurtzite form. The energy-dispersive X-ray (EDX) spectrometry shows Zn and O elements in the products with an approximate molar ratio. TEM image of ZnO thin film shows that a grain of about 60-80 nm in size is really an aggregate of many small crystallites of around 10-20 nm. Electron diffraction pattern shows that the ZnO films exhibited hexagonal structure. The SEM micrograph showed that the films consist in nanocrystalline grains randomly distributed with voids in different regions. The dc conductivity found in the range of 10-5-10-6 (Ω cm)-1. The optical study showed that the spectra for all samples give the transparency in the visible range

    FORMULATION, OPTIMIZATION AND EVALUATION OF FLOATING TABLETS CLARITHROMYCIN

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    Objective: The present aim of this study was to formulate, optimize and evaluation of floating tablets of Clarithromycin.Methods: Floating tablets of Clarithromycin were formulated using polymer HPMC K15M with sodium bicarbonate as gas generating agent by wet granulation method. A 32 factorial design were applied to systematically optimize the drug release profile. The amount of citric acid (X1) and concentration of polymer HPMC K15M (X2) was selected as independent variables. The drug release at 6 hours (Q6) and drug release at 12 hour (Q12), and diffusion exponent (n) was selected as dependent variables.Results: The results of factorial design indicated that low level of HPMC K15M favors the preparation of floating controlled release of Clarithromycin tablets. The tablets were evaluated for thickness, hardness, weight variation, floating lag time, total floating time, swelling index, drug content uniformity and in vitro drug release in 0.1N HCL (pH 1.2). The in vitro dissolution profiles of all the prepared Clarithromycin floating drug delivery system formulations was found to extend the drug release over a period of 10 to 12 hours and the drug release rate decreased with increase in polymer concentration.Conclusion: It can be concluded that the decreased in citric acid concentration in the formulation showed decreased in drug release, this is due to citric acid reaction with sodium bicarbonate resulting generation of carbon dioxide gas at a faster rate, increased rate of drug release. Increasing the concentration of HPMC K15M resulted in reduction of drug release

    Comparative economics of rural and periurban dairy farming in Kalaburagi district of Karnataka

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    Cost of milk production is an important economic indicator in assessing the farm household efficiency in milk production as well as basis for price fixation. The study was undertaken to analyse the cost and returns of milk production in rural and periurban dairy farms of Kalaburagi district of Karnataka. The per day maintenance cost in periurban dairy farms (` 150.64) was highest compared to rural dairy farms (` 91.29)for local cows, crossbred cows and buffaloes. Among total maintenance costs of periurban dairy farming, feed and fodder costs accounted major share (73.49%) followed by labour cost (15.53%) and total fixed cost (7.73%). The return per litre of milk was highest (` 8.91) for crossbred cows followed by buffalo (` 4.82) and local cows (` 0.14). The net return from crossbred cow was more than that of buffalo and local cows indicating higher profitability in rearing crossbred cow in the study area

    Clinicopathological study of hysterectomised specimens

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    Background: Hysterectomy is the commonest major surgical procedure performed in gynecology. It can be done by abdominal or vaginal route and with the help of laparoscopy. Hysterectomy is an effective treatment option for many conditions like fibroid, abnormal uterine bleeding, endometriosis, adenomyosis, uterine prolapse, pelvic inflammatory disease and cancer of reproductive organ when other treatment options are contraindicated or have failed, or if the woman no longer wishes to retain her menstrual and reproductive. The aim and objective of the study was to correlate indications of hysterectomy with histopathological findings in hysterectomised patients.Methods: A retrospective study was carried on 113 hysterectomised cases over a period of one year from June 2015 to May 2016. The data regarding the patient’s age, parity, clinical diagnosis, type of hysterectomy and histopathological diagnosis were reviewed by the records and analyzed.Results: A total of 113 cases of hysterectomies were studied. Hysterectomies were distributed over a wide age ranging from 20 years to 75 years. Most common age group was 41-50 years. Among hystectomies majority were done through vaginal route 86 (76.1%) and 26 (23%) cases were done through abdominal route. Most common clinical diagnosis was fibroid uterus in 44(38.9%) cases. Most of the hysterectomies were done for benign conditions. In final histopathological report most common diagnosis was fibroid uterus in 45(39.8%) hysterectomy specimens. It was correlated well with clinical diagnosis. Next most common histopathological diagnosis was Adenomyosis.Conclusions: Histopathological analysis correlated well with preoperative clinical diagnosis in majority of cases. The commonest indication and histopathological finding in our study was fibroid uterus. Next most common histopathological finding was Adenomyosis. Most commonly hysterectomies were done through vaginal route in our study

    Automation of Universal Testing machine using Human Machine Interface (HMI)

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    In the material strength test, stress and strain rate are often required to be constant. For example, during the cement quality inspection, the loading rate is required to be2.4 ± 0.2KN/S [1]; when measuring the upper and lower yielding points of metallic materials, the stain rate should stay between 0.00025/S and 0.0025/S; In the determination of elongation at break, the stress rate should stay in the range of 1-10N/mm2 S-1 when the elasticity modulus smaller than 150000 N/mm2 [2]. Since 1950s, Material Testing Machines, which adopted large-flow electro-hydraulic servo, valve to form control system, have appeared in developed countries. Control system of this type could meet the requirements for the stress and strain rate in the material strength test. For example, MTS and Instron from USA, Schench from German, and Shimadzu from Japan all adopted this type of system. With the improvement of the manufacturing level of proportional valve and the development of control technology, electro-hydraulic proportional valve began to be used as the main control part home and abroad [4]. However, this type of parts, which is vulnerable to pollution, requires medium of high cleanliness. It is of large noise and high price. This type of system could go wrong easily for the complex hydraulic system DOI: 10.17762/ijritcc2321-8169.15017

    Processing of Sorghum From Different Varieties and Hybrids for Semolina and Their Products

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    The present study was undertaken with the objective to standardise procedures for preparation of semolina (rava) from sorghum, to identify the best genotype for preparation of semolina and to study the nutritional quality parameters of semolina. For processing of sorghum, ten varieties and five hybrids were used for preparation of semolina and their products. A process has been standardized for semolina preparation using ultra grinding mill from sorghum grain. The semolina yield ranged from 46.51% to 54.29%. Hybrid CSH-15R gave the highest yield of semolina (54.29%). Starch content in semolina ranged from 59.93% to 66.43%. The new genotypes Phule Vasudha, Phule Yashoda and M 35-1 showed higher levels of starch content as compared to the other genotypes. The Phule Vasudha and Selection-3 showed higher levels of total soluble sugars in grains, as well as in semolina than the other genotypes. Phule Maulee gave higher level of crude fibre content (3.12%). The amino acid profile of sorghum grain and semolina showed very minor differences in the content due to the processing of sorghum grains into various products like semolina. The new genotypes of rabi sorghum showed comparable results for the mineral with that of hybrids. The organoleptic properties of the sweet (shira), upama and idali prepared from semolina were judged on the basis of colour, texture and appearance, flavour, taste and overall acceptability of the products using semi-trained judges and 1 to 9 hedonic scales. All products prepared from semolina were like very much and gave highest rating of more than 8 hedonic scales. While considering the yield of semolina from sorghum grains as well as their nutritional composition and organoleptic properties of the niche products (shira, upama, idali) prepared from them, the varieties Phule Vasudha and Phule Yashoda were the best one as compared to the other varieties and hybrids and overall varieties were better than the hybrids

    Nondescent vaginal hysterectomy: analysis of indications and complications

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    Background: Hysterectomy is the commonest major surgical procedure performed in gynecology. It can be done by abdominal or vaginal route and with the help of laparoscopy. Laparoscopic assisted vaginal hysterectomy (LAVH) and total laparoscopic hysterectomy (TLH) although gaining more popularity now a days, though it is associated with higher cost, longer duration of operation, and need general anaesthesia. The latest value study concluded that major haemorrhage, hematoma, ureteric injury, bladder injury, and anesthetic complications were more in laparoscopic assisted hysterectomy (LAVH) group when compared to abdominal and vaginal hysterectomies. In addition LAVH was accomplished in twice the time required for vaginal hysterectomy.The objective of the study was to analyse the indication and to study the complications of nondescent vaginal hysterectomy.Methods: This is a retrospective cohort study.  60 women who underwent nondescent vaginal hysterectomy in the department of OBG, B.G.S. Global Institute of Medical Sciences, Banglore, India were included in the study. Patients’ records were retrieved. Data regarding patient’s age, parity, indications for hysterectomy, uterine size in weeks, previous surgeries in the past, duration of surgery and complications were recorded. Data collected on a semi structured proforma and the same was analysed using suitable statistical analysis.Results: A total of 60 cases were operated for different indications. Among the study participants majority were in the age group of 41-45 years with 28 (46.7%). Most common indication for hysterectomies were dysfunctional uterine bleeding (DUB) with 27 (45%), followed by fibroid uterus 15 (25%). The mean duration of surgery time taken was 50+10minutes. Majority of the women who underwent hysterectomies had bulky uterus with 42 (70%).  Complications were very few. Fever, UTI (urinary tract infection) and headache were seen in 3 (5%) cases. There was one case of vault sepsis and one case of upper respiratory tract infection (URTI). In one patient vaginal hysterectomy could not be completed and abdominal hysterectomy was carried out. Mean hospital duration was 4 days.Conclusions: Vaginal hysterectomy is the least invasive with fewer complications and most economical route for hysterectomy. Nondescent vaginal hysterectomy should be the gynaecologists first choice for hysterectomy
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