44,144 research outputs found
Chiral effective field theory beyond the power-counting regime
Novel techniques are presented, which identify the chiral power-counting
regime (PCR), and realize the existence of an intrinsic energy scale embedded
in lattice QCD results that extend outside the PCR. The nucleon mass is
considered as a benchmark for illustrating this new approach. Using
finite-range regularization, an optimal regularization scale can be extracted
from lattice simulation results by analyzing the renormalization of the low
energy coefficients. The optimal scale allows a description of lattice
simulation results that extend beyond the PCR by quantifying and thus handling
any scheme-dependence. Preliminary results for the nucleon magnetic moment are
also examined, and a consistent optimal regularization scale is obtained. This
indicates the existence of an intrinsic scale corresponding to the finite size
of the source of the pion cloud.Comment: 6 pages, 4 figures, conferenc
Close encounters involving free-floating planets in star clusters
Instabilities in planetary systems can result in the ejection of planets from
their host system, resulting in free-floating planets (FFPs). If this occurs in
a star cluster, the FFP may remain bound to the star cluster for some time and
interact with the other cluster members until it is ejected. Here, we use
-body simulations to characterise close star-planet and planet-planet
encounters and the dynamical fate of the FFP population in star clusters
containing single or binary star members. We find that FFPs ejected
from their planetary system at low velocities typically leave the star cluster
40% earlier than their host stars, and experience tens of close ( AU)
encounters with other stars and planets before they escape. The fraction of
FFPs that experiences a close encounter depends on both the stellar density and
the initial velocity distribution of the FFPs. Approximately half of the close
encounters occur within the first 30 Myr, and only 10% occur after 100 Myr. The
periastron velocity distribution for all encounters is well-described by a
modified Maxwell-Bolzmann distribution, and the periastron distance
distribution is linear over almost the entire range of distances considered,
and flattens off for very close encounters due to strong gravitational
focusing. Close encounters with FFPs can perturb existing planetary systems and
their debris structures, and they can result in re-capture of FFPs. In
addition, these FFP populations may be observed in young star clusters in
imaging surveys; a comparison between observations and dynamical predictions
may provide clues to the early phases of stellar and planetary dynamics in star
clusters.Comment: Accepted for publication in MNRAS; 18 pages, 12 figure
Effects of deleting cannabinoid receptor-2 on mechanical and material properties of cortical and trabecular bone
Acknowledgements We thank Dr J.S. Gregory for assistance with Image J and Mr K. Mackenzie for assistance with Micro-CT analysis. Funding ABK was funded by a University of Aberdeen, Institute of Medical Sciences studentship and the Overseas Research Students Awards Scheme.Peer reviewedPublisher PD
Mechanical and material properties of cortical and trabecular bone from cannabinoid receptor-1-null (Cnr1-/-) mice
Funding ABK was funded by a studentship from the University of Aberdeen, Institute of Medical Sciences, and the Overseas Research Students Awards Scheme Acknowledgments We are grateful to Dr J.S. Gregory for assistance with Image J and Mr K. Mackenzie for assistance with Micro-CT analysis.Peer reviewedPostprin
In-vivo magnetic resonance imaging of hyperpolarized silicon particles
Silicon-based micro and nanoparticles have gained popularity in a wide range
of biomedical applications due to their biocompatibility and biodegradability
in-vivo, as well as a flexible surface chemistry, which allows drug loading,
functionalization and targeting. Here we report direct in-vivo imaging of
hyperpolarized 29Si nuclei in silicon microparticles by MRI. Natural physical
properties of silicon provide surface electronic states for dynamic nuclear
polarization (DNP), extremely long depolarization times, insensitivity to the
in-vivo environment or particle tumbling, and surfaces favorable for
functionalization. Potential applications to gastrointestinal, intravascular,
and tumor perfusion imaging at sub-picomolar concentrations are presented.
These results demonstrate a new background-free imaging modality applicable to
a range of inexpensive, readily available, and biocompatible Si particles.Comment: Supplemental Material include
Flavor Delta(54) in SU(5) SUSY Model
We design a supersymmetric SU (5) GUT model using \Delta (54), a finite
non-abelian subgroup of SU (3)f . Heavy right handed neutrinos are introduced
which transform as three-dimensional repre-sentation of our chosen family
group. The model successfully reproduces the mass hierarchical mass structures
of the Standard Model, and the CKM mixing matrix. It then provides predictions
for the light neutrino with a normal hierarchy and masses such that m{\nu},1
\approx 5\times10-3 eV, m{\nu}, 2 \approx 1\times 10-2 eV, and m{\nu},3 \approx
5 \times 10-2 eV. We also provide predictions for masses of the heavy
neutrinos, and correc- tions to the tri-bimaximal matrix that fit within
experimental limits, e.g. a reactor angle of -7.31o. A simple modification to
our model is introduced at the end and is shown to also produce predictions
that fall well within those limits.Comment: 22 page
Beef Cattle Instance Segmentation Using Fully Convolutional Neural Network
In this paper we present a novel instance segmentation algorithm that extends a fully convolutional network to learn to label objects separately without prediction of regions of interest. We trained the new algorithm on a challenging CCTV recording of beef cattle, as well as benchmark MS COCO and Pascal VOC datasets. Extensive experimentation showed that our approach outperforms the state-of-the-art solutions by up to 8% on our data
Lactobacillus ruminis strains cluster according to their mammalian gut source
peer-reviewedBackground
Lactobacillus ruminis is a motile Lactobacillus that is autochthonous to the human gut, and which may also be isolated from other mammals. Detailed characterization of L. ruminis has previously been restricted to strains of human and bovine origin. We therefore sought to expand our bio-bank of strains to identify and characterise isolates of porcine and equine origin by comparative genomics.
Results
We isolated five strains from the faeces of horses and two strains from pigs, and compared their motility, biochemistry and genetic relatedness to six human isolates and three bovine isolates including the type strain 27780T. Multilocus sequence typing analysis based on concatenated sequence data for six individual loci separated the 16 L. ruminis strains into three clades concordant with human, bovine or porcine, and equine sources. Sequencing the genomes of four additional strains of human, bovine, equine and porcine origin revealed a high level of genome synteny, independent of the source animal. Analysis of carbohydrate utilization, stress survival and technological robustness in a combined panel of sixteen L. ruminis isolates identified strains with optimal survival characteristics suitable for future investigation as candidate probiotics. Under laboratory conditions, six human isolates of L. ruminis tested were aflagellate and non-motile, whereas all 10 strains of bovine, equine and porcine origin were motile. Interestingly the equine and porcine strains were hyper-flagellated compared to bovine isolates, and this hyper-flagellate phenotype correlated with the ability to swarm on solid medium containing up to 1.8% agar. Analysis by RNA sequencing and qRT-PCR identified genes for the biosynthesis of flagella, genes for carbohydrate metabolism and genes of unknown function that were differentially expressed in swarming cells of an equine isolate of L. ruminis.
Conclusions
We suggest that Lactobacillus ruminis isolates have potential to be used in the functional food industry. We have also identified a MLST scheme able to distinguish between strains of L. ruminis of different origin. Genes for non-digestible oligosaccharide metabolism were identified with a putative role in swarming behaviour.This work was supported by a Principal Investigator Award (07/IN.1/B1780)
from Science Foundation Ireland to P.W. O’Toole
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