Proximate and Elemental Analysis of Cowpea, Kidney and Sweet Cowpea Beans Sold in Kawo Market, Kaduna State, Nigeria

Beans are one of the most popular and essential foods in Africa, especially in Nigeria they are highly recommended for its numerous health benefits and nutritional values. The objective of this paper is to assess the proximate and elemental compositions of three (3) varieties of beans (cowpea, kidney and sweet cowpea beans) marketed in Kawo, Kaduna State, Nigeria using standard procedures and atomic absorption spectroscopy (AAS). The results from this study indicated that the highest results obtained for proximate and elemental analysis in the four (4) samples with the exception of fibre in sweet cowpea beans (2.082%), were found to be: moisture (13.250%), protein (21.420%), Lipids (1.025%), ash (4.814%) in kidney beans while in the case of elemental analysis, the highest concentrations (88.0mg/kg) of Zn was found in (Cowpea bean), (52.5mg/kg) of Mg in sweet cowpea, (75.0mg/kg) of Cu in cowpea beans while Fe (99.5mg/kg) and Ca (99.5mg/kg) were found in kidney beans. All the beans samples analyzed for proximate and elemental analysis from Kawo market are highly nutritious, hence good for human and livestock consumption

A Review of Stream Regimes Manipulation System Effects on Drainage Basin and Remedies

Naturally, a drainage basin harbours stream flow and channel characteristics in an open system. Urbanization effects on hydrological cycles and on stream morphology and dynamics, as in Anderson (1970) causes naturalized changes in channel characteristics as explained (Mrowka, 1974; Sehumm1977) and flood plain characteristics. These man’s efforts and their consequences draw several attentions to changing channel morphology and hydraulic geometry of stream channels by studies such as in Troxell and Leopold(1971), Hammer(1972), Knox(1977), Knight(1979), Morisawa and Vemure (1976), Morisawa and Laflurem(1979), Ebisemijiu (1989). Such situation reviewed in this paper have disturbed the entire watershed and channels as emaciated in the works of Simon (1992), Simon and Hupp (1992), Oyegun (1994), Church (1992), Pizzuto (1994), Elliot and  Gyetuai (1999)

Knowledge, Attitude and Practice Towards Sexually Transmitted Diseases among Undergraduate Students in Ahmadu Bello University, Main Campus, Samaru, Zaria.

Background: Worldwide, over a million people acquire a sexually transmitted infection (STI) daily. Young individuals of 16-24years age group are more prone to STIs because they lack adequate knowledge about STIs and tend to have wrong perceptions towards sex. Aim: This study aims to assess the knowledge, attitude, and practice towards sexually transmitted diseases among undergraduate students of ABU main campus, Samaru, Zaria. Methods: A descriptive cross-sectional survey design was used, in which 440 questionnaires were administered for the study among which 411(93%) were retrieved and analyzed using Statistical Package for Social Science (SPSS) version 23. Results: Results obtained showed that 77% of the respondents had good knowledge, attitudes of the respondents were found to be positive with an aggregate mean of 4.12 and 67% uses a condom for the prevention of sexually transmitted diseases. Conclusion: From the findings of the study, it was concluded that undergraduate students in Ahmadu Bello University Zaria had good knowledge, positive attitudes, and good preventive practices towards sexually transmitted diseases

Introducing a Manipulated System of Drainage Basins of a Developing Countries

As a natural open system, in a drainage basin, there is water flow and balanced channel characteristics. In a manipulated channel system, however, according to Mrowka (1974) and Schumm (1977), the water flow is made under control that induces dynamics in channel characteristics. In this paper, attempt is made to uncover how channel project is caused, nature of the new forms of channel cross-sectional area, shape, sinuosity, and gradient, as well as flood-plain characteristics. It also covers the peculiar transformation evolved as drainage basin system is changed to channel project. Consequently in the paper, two tasks involved were explained. These are significant channel re-construction, and redirection of stream flow as relates to developing water terrace in the savanna zone of Nigeria with the increased channel project dated back 1970s (Olofin, 1980). Specifically, the paper drew considered the physical characteristics of the natural channel of River Suka in North Central Nigeria and the manipulated system or the new face of the drainage basin project of the Kano River, Nigeria used to structure the Tiga dam that involved downstream channel adjustments Keywords: drainage basin, channel, river, dam, downstrea

Health Risks Associated with Consumption of Vegetables Grown using Domestic Wastewater in Minna, Niger State, Nigeria

Most vegetables consumed in the cities of developing countries are grown using wastewater discharged through township drainage network. This paper, therefore, investigates the risk involved in the consumption of such vegetables. The human daily intake rate (DIR) and Health Risk Index (HRI) of heavy metals were calculated using established formulae and the values of DIR ranged from 0.10 mg/kg/day to 0.71 mg/kg/day in wastewater plots in dry season for adults and 0.10 mg/kg/day to 0.14 mg/kg/day for children. Health risk index (HRI) values ranges from 0.40 mg/kg/day to 0.75 mg/kg/day in wastewater plots for adults in dry season and 0.20 mg/kg/day to 0.95 mg/kg/day for children. In wet season wastewater plots, the HRI ranges from 0.40 mg/kg/day to 0.95 mg/kg/day for children. The values of Hazard index (HI) ranged between 1.00 mg/kg/day and 1.21 mg/kg/day for all the seasons. Statistical analysis showed that there is a significant difference between the wet and dry season values for all the parameters assessed. Finally, uptake of heavy metals from the soil by all the vegetable crops under investigation was established. Therefore proper monitoring needs to be carried out to regulate consumption of vegetables produced from the experimental sites as continuous application of the industrial wastewater may lead to further accumulation of these heavy metals

Evaluation of neutrophil gelatinase associated lipocalin (NGAL) in type 2 diabetic patients with diabetic nephropathy

Diabetic nephropathy (DN) is a devastating chronic microvascular complication that represents the major cause of end-stage renal failure leading to the development and progression of diabetic syndrome. Aim: The aim of this study was to evaluate serum neutrophil gelatinase associated lipocalin (NGAL) in type 2 DM with diabetic nephropathy. Methods: Eighty (80) type 2 diabetic patients with DN and apparently healthy controls were respectively recruited. Blood samples were collected and tested for serum NGAL, creatinine, albumin, fasting plasma glucose and HbA1c. Creatinine and albumin were analyzed using Abbot autoanalyser, HbA1c was analyzed using fine care system and serum NGAL using the ELISA method. Estimated GFR (eGFR) was calculated using the modification of diet in renal disease (MDRD) formula. Statistical analysis was performed using statistical package for social science (SPSS) software version 20.0. Student t-test, one way analysis of variance (ANOVA) and Pearson’s correlation were used for comparisons and correlation of data respectively with level of significance set <0.05. Result: The mean values of the serum NGAL, FPG, HbA1c, BMI and eGFR in both DN group and control group were found to be 3.72±2.62 vs 1.08±0.78μg/ml, 7.06 ±3.46 vs 4.08± 0.39mmo/l, 6.73±1.08 vs 4.71 ±0.39%, 27.33±5.29 vs 25.08±3.65ml/min/1.73m2 and 76.57 ±11.20 vs 118.23 ±12.11ml/min/1.73m2 respectively. The study found a high and significant difference in the mean values of the DN group compared to the control group. A positive and significant relationship was observed between serum NGAL and eGFR and duration of diagnosis of diabetes mellitus. Conclusion: Serum NGAL could therefore be used as a biomarker to diagnose DN even earlier to incipient nephropathy, NGAL, Diabetes nephropathy, eGFR, Microalbuminuria, Glycated haemoglobin

Determinants of prostate specific antigen screening test uptake in an urban community in North-Central Nigeria

Background: Despite the increasing incidence of Prostate cancer, there has not been any focused screening policy or strategy in sub-Saharan Africa including Nigeria.Objectives: To assess the level of awareness and uptake of PSA screening test and their determinants in a Nigerian community.Methods: A cross-sectional population survey of men with no prior history of prostate cancer was carried out. Logistic re- gression analysis was used to determine the effect of identified variables in predicting awareness and uptake of prostate cancer screening.Results: Mean age was 51.5±9.8 years; a few men (31, 16.9%) had ever heard of the screening test and most got the information from health centers. A low proportion (8, 4.4%) had taken the screening test. Men with incomes above poverty line (OR = 11.7 2.8–50.1, p = .001) or those with health insurance (OR = 2.7 1.2–6.5, p = .023) were significantly more likely to be aware of the test. Only the men with higher incomes (OR = 25.6 5.8–114.2, p = .0001) were significantly more likely to have taken the test.Conclusion: Higher incomes and health insurance status impact screening awareness but only income status determines if men subsequently proceed to take the PSA screening test.Keywords: Prostate cancer; PSA screening; sub-Saharan Africa; Nigeria

High Impedance Fault Detection and Localization Using Fully-Connected Convolutional Neural Network: A Deep Learning Approach

The detection and localization of high impedance faults (HIF) in power systems are challenging due to the low fault current magnitude, which often falls below the detection threshold of conventional devices. HIF events introduce harmonics into the network, posing risks to the safety of connected equipment, including the potential for igniting fire which endangers lives and properties. In this study, Emanuel's HIF model was used to generate HIF signatures resembling real HIF events. Model parameters were adjusted to mimic various contact surface impedances. Two datasets were created: 'no-fault' data, simulating the network without HIF, and 'fault' data, incorporating HIF waveforms by simulating single and multiple lines with the HIF model. The faulted line was divided into five segments along the 33 kV line to capture fault signatures at different locations. The generated data, including current waveforms and magnitudes, were processed and divided into an 80:20 ratio for training, validation, and testing using a deep fully connected Convolutional Neural Network for HIF detection and location. The results showed an impressive accuracy rate of 99.44% and 99.78% for detection and location respectively, representing a significant advancement in HIF detection and location, and offering practical applications for enhancing power line safety

Effects on quality of life, anti-cancer responses, breast conserving surgery and survival with neoadjuvant docetaxel: a randomised study of sequential weekly versus three-weekly docetaxel following neoadjuvant doxorubicin and cyclophosphamide in women with primary breast cancer

<p>Abstract</p> <p>Background</p> <p>Weekly docetaxel has occasionally been used in the neoadjuvant to downstage breast cancer to reduce toxicity and possibly enhance quality of life. However, no studies have compared the standard three weekly regimen to the weekly regimen in terms of quality of life. The primary aim of our study was to compare the effects on QoL of weekly versus 3-weekly sequential neoadjuvant docetaxel. Secondary aims were to determine the clinical and pathological responses, incidence of Breast Conserving Surgery (BCS), Disease Free Survival (DFS) and Overall Survival (OS).</p> <p>Methods</p> <p>Eighty-nine patients receiving four cycles of doxorubicin and cyclophosphamide were randomised to receive twelve cycles of weekly docetaxel (33 mg/m²) or four cycles of 3-weekly docetaxel (100 mg/m²). The Functional Assessment of Cancer Therapy-Breast and psychosocial questionnaires were completed.</p> <p>Results</p> <p>At a median follow-up of 71.5 months, there was no difference in the Trial Outcome Index scores between treatment groups. During weekly docetaxel, patients experienced less constipation, nail problems, neuropathy, tiredness, distress, depressed mood, and unhappiness. There were no differences in overall clinical response (93% vs. 90%), pathological complete response (20% vs. 27%), and breast-conserving surgery (BCS) rates (49% vs. 42%). Disease-free survival and overall survival were similar between treatment groups.</p> <p>Conclusions</p> <p>Weekly docetaxel is well-tolerated and has less distressing side-effects, without compromising therapeutic responses, Breast Conserving Surgery (BCS) or survival outcomes in the neoadjuvant setting.</p> <p>Trial registration</p> <p>ISRCTN: <a href="http://www.controlled-trials.com/ISRCTN09184069">ISRCTN09184069</a></p

GEneSTATION 1.0: A Synthetic Resource of Diverse Evolutionary and Functional Genomic Data for Studying The Evolution of Pregnancy-Associated Tissues and Phenotypes

Mammalian gestation and pregnancy are fast evolving processes that involve the interaction of the fetal, maternal and paternal genomes. Version 1.0 of the GEneSTATION database (http://genestation.org) integrates diverse types of omics data across mammals to advance understanding of the genetic basis of gestation and pregnancy-associated phenotypes and to accelerate the translation of discoveries from model organisms to humans. GEneSTATION is built using tools from the Generic Model Organism Database project, including the biology-aware database CHADO, new tools for rapid data integration, and algorithms that streamline synthesis and user access. GEneSTATION contains curated life history information on pregnancy and reproduction from 23 high-quality mammalian genomes. For every human gene, GEneSTATION contains diverse evolutionary (e.g. gene age, population genetic and molecular evolutionary statistics), organismal (e.g. tissue-specific gene and protein expression, differential gene expression, disease phenotype), and molecular data types (e.g. Gene Ontology Annotation, protein interactions), as well as links to many general (e.g. Entrez, PubMed) and pregnancy disease-specific (e.g. PTBgene, dbPTB) databases. By facilitating the synthesis of diverse functional and evolutionary data in pregnancy-associated tissues and phenotypes and enabling their quick, intuitive, accurate and customized meta-analysis, GEneSTATION provides a novel platform for comprehensive investigation of the function and evolution of mammalian pregnancy