Клиническое наблюдение мультиорганной резекции при местно-распространенном раке левой половины толстой кишки

The article discusses the tactics and results of treatment of locally advanced colon cancer. We consider the reasonability of multivisceral colon resections in locally advanced colon cancer. The clinical case of locally advanced cancer of the left half of the colon, which got combined treatment, is presented.В статье рассматриваются тактика и результаты лечения местно-распространенного рака ободочной кишки. Обсуждается целесообразность выполнения мультивисцеральных резекций ободочной кишки. Представлен клинический случай пациента с местно-распространенным раком левой половины ободочной кишки, которому проведено комбинированное лечение

Definition and scope of the surgical treatment in patients with pulmonary metastases from colorectal cancer

Surgical treatment of metastatic colorectal cancer in lungs is a relatively new trend of modern oncology. In this connection, still there are no clearly formulated criteria for patient selection for this type of intervention, approaches to repeated resections and scope of the surgical operation in case of multiple lesions. Established key prognostic factors include lesion of intrathoracic lymph nodes, timing of the development of metastatic disease, baseline level of carcinoembryonic antigen, number of foci and the volume of metastatic lesion, stage of the disease. Options for surgical access include lateral thoracotomy, sternotomy, thoracoscopy and thoracoscopy combined with additional minithoracotomy.If a patient has a single peripheral metastatic lesions, physician should prefer thoracoscopic operations. One of their advantages include minimum development of adhesions and possibility of subsequent re-thoracoscopy. Resection of pulmonary metastases from colorectal cancer (R0 resection rate) allows to achieve persistent healing of the tumor process in a significant number of patients

Clinical case of multiorgan resection for locally advanced cancer of the left half of the colon

The article discusses the tactics and results of treatment of locally advanced colon cancer. We consider the reasonability of multivisceral colon resections in locally advanced colon cancer. The clinical case of locally advanced cancer of the left half of the colon, which got combined treatment, is presented

Определение показаний и объема хирургического лечения больных с метастазами колоректального рака в легкие

Surgical treatment of metastatic colorectal cancer in lungs is a relatively new trend of modern oncology. In this connection, still there are no clearly formulated criteria for patient selection for this type of intervention, approaches to repeated resections and scope of the surgical operation in case of multiple lesions. Established key prognostic factors include lesion of intrathoracic lymph nodes, timing of the development of metastatic disease, baseline level of carcinoembryonic antigen, number of foci and the volume of metastatic lesion, stage of the disease. Options for surgical access include lateral thoracotomy, sternotomy, thoracoscopy and thoracoscopy combined with additional minithoracotomy.If a patient has a single peripheral metastatic lesions, physician should prefer thoracoscopic operations. One of their advantages include minimum development of adhesions and possibility of subsequent re-thoracoscopy. Resection of pulmonary metastases from colorectal cancer (R0 resection rate) allows to achieve persistent healing of the tumor process in a significant number of patients.Хирургическое лечение метастазов колоректального рака в легкие – сравнительно новое направление современной онкологии. В связи с этим до сих пор четко не сформулированы критерии отбора пациентов для подобных вмешательств, подходы к повторным резекциям и выбор объема операции при множественном поражении. Установленными ключевыми прогностическими факторами являются поражение внутригрудных лимфатических узлов, сроки развития метастатического заболевания, исходный уровень раково-эмбрионального антигена, число очагов и объем  метастатического поражения, стадия заболевания. Варианты хирургического доступа включают боковую торакотомию, стернотомию, торакоскопию и торакоскопию с дополнительной мини-торакотомией. При наличии единичных периферических метастатических очагов предпочтение следует отдавать торакоскопическим операциям, одним из преимуществ которых является минимальное развитие спаечного процесса и возможность последующей реторакоскопии. Выполнение резекций метастазов колоректального рака в легкие в объеме R0 позволяет достичь стойкого излечения опухолевого процесса у значительного числа больных

Experience of Cancer Research Center in the treatment of advanced germ cell tumors

The experience of CRC in the treatment of advanced germ cell tumors is reported. The analysis of factors influencing prognosis and treatment tactics is carried out. Contemporary conception of advanced germ cell tumors treatment implies the initial use of platinum based chemotherapy. After completion of chemotherapy, surgical removal of residual tumor (retroperitoneal and mediastinal lymph nodes, lung and liver metastases) carries diagnostic and curative means. Such approach allows curing 50-90% of patients depending on prognostic factors. Results of induction chemotherapy for relapses of germ cell tumors are presented separately. Treatment of this condition comprises chemotherapy with inclusion of ifosfamid or taxanes with following cytoreductive surgery. This modality allows long term remission in the fourth of patients with relapse of germ cell tumors