Optimasi Pemerataan Tingkat Terang Cahaya Pada Rancangan Ruang Kelas Bangunan Pendidikan Nonformal Di Kota Malang

Perkembangan dunia pendidikan nonformal di Kota Malang hingga tahun 2014 tercatat terdapat 225 Lembaga Pendidikan nonformal yang berdiri. Berdasarkan hasil analisa data dari instansi-instansi terkait, 68% lembaga pendidikan nonformal menempati bangunan yang belum memenuhi standar. Hal ini dikarenakan belum adanya bangunan pendidikan terencana khusus untuk pendidikan nonformal di Kota Malang. Rancangan bangunan pusat pendidikan nonformal merupakan solusi untuk mengatasi masalah tersebut. Dalam bangunan pendidikan, pencahayaan ruang kelas merupakan faktor penting, karena dapat mempengaruhi efektifitas dan efisiensi kegiatan belajar. Kegiatan belajar-mengajar yang berlangsung di ruang kelas tidak tergantung cuaca, sehingga membutuhkan bantuan pencahayaan buatan untuk memenuhi Kenyamanan kebutuhan visual. Dibutuhkan perencanaan kondisi pencahayaan yang tepat antara pencahayaan alami dan buatan, agar keberadaan cahaya buatan bersinergi dengan kondisi cahaya alami. Kajian perancangan ini menggunakan metode deskriptif kualitatif dan dalam proses evaluasi pencahayaan ruang kelas dengan metode simulasi menggunakan software DIALux 4.12. Hasilnya untuk menghadirkan kondisi pencahayaan yang optimal pemerataan tingkat terang/illuminance setiap waktu, diwujudkan dengan perencanaan sistem kontrol cahaya pasif dan aktif

Fast and low cost analysis of dioxin and dioxin-like compounds in marine matrices: final report

0info:eu-repo/semantics/publishe

Recursiveness, Switching, and Fluctuations in a Replicating Catalytic Network

A protocell model consisting of mutually catalyzing molecules is studied in order to investigate how chemical compositions are transferred recursively through cell divisions under replication errors. Depending on the path rate, the numbers of molecules and species, three phases are found: fast switching state without recursive production, recursive production, and itinerancy between the above two states. The number distributions of the molecules in the recursive states are shown to be log-normal except for those species that form a core hypercycle, and are explained with the help of a heuristic argument.Comment: 4 pages (with 7 figures (6 color)), submitted to PR

Phenotype-driven approaches to enhance variant prioritization and diagnosis of rare disease.

Rare disease diagnostics and disease gene discovery have been revolutionized by whole-exome and genome sequencing but identifying the causative variant(s) from the millions in each individual remains challenging. The use of deep phenotyping of patients and reference genotype-phenotype knowledge, alongside variant data such as allele frequency, segregation, and predicted pathogenicity, has proved an effective strategy to tackle this issue. Here we review the numerous tools that have been developed to automate this approach and demonstrate the power of such an approach on several thousand diagnosed cases from the 100,000 Genomes Project. Finally, we discuss the challenges that need to be overcome if we are going to improve detection rates and help the majority of patients that still remain without a molecular diagnosis after state-of-the-art genomic interpretation