The Influence of Perceptual Training on Working Memory in Older Adults

Normal aging is associated with a degradation of perceptual abilities and a decline in higher-level cognitive functions, notably working memory. To remediate age-related deficits, cognitive training programs are increasingly being developed. However, it is not yet definitively established if, and by what mechanisms, training ameliorates effects of cognitive aging. Furthermore, a major factor impeding the success of training programs is a frequent failure of training to transfer benefits to untrained abilities. Here, we offer the first evidence of direct transfer-of-benefits from perceptual discrimination training to working memory performance in older adults. Moreover, using electroencephalography to evaluate participants before and after training, we reveal neural evidence of functional plasticity in older adult brains, such that training-induced modifications in early visual processing during stimulus encoding predict working memory accuracy improvements. These findings demonstrate the strength of the perceptual discrimination training approach by offering clear psychophysical evidence of transfer-of-benefit and a neural mechanism underlying cognitive improvement

Chronic lymphocytic leukaemia Australasian consensus practice statement

Chronic lymphocytic leukaemia (CLL) is the most common haematological malignancy in Australia and New Zealand (ANZ). Considerable changes to diagnostic and management algorithms have occurred within the last decade. The availability of next-generation sequencing and measurable residual disease assessment by flow cytometry allow for advanced prognostication and response assessments. Novel therapies, including inhibitors of Bruton's tyrosine kinase (BTKi) and B-cell lymphoma 2 (BCL2) inhibitors, have transformed the treatment landscape for both treatment-naïve and relapsed/refractory disease, particularly for patients with high-risk genetic aberrations. Recommendations regarding appropriate supportive management continue to evolve, and special considerations are required for patients with CLL with respect to the global SARS-CoV-2 pandemic. The unique funding and treatment environments in Australasia highlight the need for specific local guidance with respect to the investigation and management of CLL. This consensus practice statement was developed by a broadly representative group of ANZ experts in CLL with endorsement by peak haematology bodies, with a view to providing this standardised guidance

On the Spatial Distribution of Visual Attention

An implication of the data analysis and presentation of Podgorny and Shepard (1983)is that subjects are able to attend simultaneously to more than one square of a grid display when the squares are separated by unattended areas: Attention to such nonunitary areas produces similar benefits as attention to unitary areas. These benefits are reflected in reaction times (RTs), which were reported by Podgorny and Shepard (1983)as being related to a measure of spatial dispersion (compactness) of the attended areas, but this measure does not signify whether these areas are unitary or not. A reanalysis of part of Podgorny and Shepard's (1983)data shows that RTs to attended and unattended squares are almost identical when the attended areas are nonunitary. This reanalysis also shows that RTs are related to compactness for unitary attended areas but that this relation breaks down when attention is focused on nonunitary areas. In addition, Podgorny and Shepard's (1983)data are presented in a way that demonstrates the importance of the actual grid location of probes on RTs. The failure of compactness to reflect these aspects of the spatial nature of attention suggests that this metric is deficient when applied to the study of the spatial determinants of attention

Curvature-specific color aftereffects

Adaptation to convex and concave arcs in different colored light results in curvature-specific color aftereffects when arcs are later viewed in white light. In three experiments, it was shown that these color aftereffects often are partial (restricted to limited regions of the test arcs) rather than uniform, and in addition that aftereffects induced by exposure to arcs transfer to straight-line displays of particular orientation, and vice versa. These data were interpreted as evidence that arcs are processed in the visual system in relation to the orientations of local straight line approximations instead of on a global basis. In these terms, curvature-specific color aftereffects are merely complex forms of the orientation-specific color aftereffects first described by McCollough (1965)

Are individual differences in temperament of relevance to Gibson\u27s theory of affordances?

The ambitious scope, complexity, and difficulty of Gibson&rsquo;s project in proposing the theory of affordances are captured nicely by the words of Gibson&rsquo;s biographer, Ed Reed:&ldquo;Gibson was convinced that the theory of affordances, inconjunction with the concepts of information, persistence, andchange, would enable him to transcend the ancient debate betweensubjectivity and objectivity and to resolve the mind-body problem. &hellip;[H]e was offering a new approach to problems of psychology, onethat he believed would not sink in the morass that have engulfedprevious psychologies.&rdquo; (Reed, 1988, p. 280).These characteristics of the theory of affordances are further evidenced in the debates about the nature of affordances presented in the suite of papers in Ecological Psychology, Volume 12(1). In this paper we propose an elaboration of the notion of affordance by suggesting that those persisting individual differences in behaviour described as temperamental differences (e.g., differences on a dimension of temperament anchored at one end by behaviour described as &lsquo;outgoingness&rsquo; and at the other by behaviour described as &lsquo;avoidance&rsquo;) can be integrated into the theory of affordances. We argue that such integration is consistent with Gibson&rsquo;s project as reflected in Reed&rsquo;s words, and as part of our argument, draw parallels between the integration of temperament with the theory of affordances and the way in which individual differences in body dimensions are incorporated in the theory. We also outline some empirical tests of our proposition.<br /