6,876 research outputs found

    The short-run dynamics of long-run inflation policy

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    An examination of the short- and long-term implications of an inflation policy on real output, using a method that allows structural interpretation of a simple VAR applied to a macroeconomic system that includes real output and inflation.Inflation (Finance) ; Monetary policy ; Gross national product

    Attitudes and reported practice of paediatricians and child psychiatrists regarding the assessment and treatment of ADHD in Ireland

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    Objectives. This mixed-method national survey has obtained original data on attention deficit hyperactivity disorder (ADHD) attitudes, assessment and treatment regimes reported by paediatricians and child psychiatrists; and has compared their clinics. It has examined the extent of involvement of Irish paediatricians in the management of ADHD. Methods. A questionnaire was designed, based on a review of literature and ADHD guidelines, and piloted by expert clinicians. Universal recruitment was conducted among Child and Adolescent Mental Health Services (CAMHS) consultants (n = 71) and community/general paediatric consultants (n = 72). Quantitative and qualitative data was collected and analysed. Results. There was an overall response rate of 43%. A dedicated ADHD clinic is offered in 79% of CAMHS services, but only in one paediatric service. Participants reported that the assessment of ADHD involves multidisciplinary work and this was only established in CAMHS clinics. Medication is initiated by 82% of child psychiatrists and only 22% of paediatricians. Conclusions. This first national study of ADHD attitudes and practices presents comprehensive data regarding the management of children with ADHD in CAMHS and paediatric settings in Ireland. Paediatricians reported a minor role in managing ADHD. Study limitations are related to subjective reporting rather than case note audit, and a moderate response rate for the paediatricians’ participants

    Classical pion fields in the presence of source

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    Classical pion field similar to Disoriented Chiral Condensate (DCC) is considered in the presence of the external source. This field is similar to DCC in the sense that its isotopic orientation is specified with a single vector at the whole space. We study the classical field solutions in the nonlinear sigma-model both in the chiral limit with massless pion and for the finite pion mass. In both cases the field resembles the Coulomb field of charged particle however the nonlinear pion interactions lead to the existence of several solutions. In the massless case and for the very small size of the source there is the lot of classical solutions with finite discrete energies. In the more realistic situation of large nucleus (heavy ion) there are no stable solutions of the above type, but there is the possibility for the formation of the quasistationary states. They can live for a long time slowly decaying through the emission of very soft pions. The structure and the energies of these solutions is investigated numerically.Comment: 10 pages, LaTeX, 1 figure, epsfig.sty, corrected typos, added reference

    On fault-tolerance with noisy and slow measurements

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    It is not so well-known that measurement-free quantum error correction protocols can be designed to achieve fault-tolerant quantum computing. Despite the potential advantages of using such protocols in terms of the relaxation of accuracy, speed and addressing requirements on the measurement process, they have usually been overlooked because they are expected to yield a very bad threshold as compared to error correction protocols which use measurements. Here we show that this is not the case. We design fault-tolerant circuits for the 9 qubit Bacon-Shor code and find a threshold for gates and preparation of p(p,g)thresh=3.76×105p_{(p,g) thresh}=3.76 \times 10^{-5} (30% of the best known result for the same code using measurement based error correction) while admitting up to 1/3 error rates for measurements and allocating no constraints on measurement speed. We further show that demanding gate error rates sufficiently below the threshold one can improve the preparation threshold to p(p)thresh=1/3p_{(p)thresh} = 1/3. We also show how these techniques can be adapted to other Calderbank-Shor-Steane codes.Comment: 11 pages, 7 figures. v3 has an extended exposition and several simplifications that provide for an improved threshold value and resource overhea

    Controlling the Size and Shape of Polypeptide Colloidal Particles: Temperature Dependence of Particle Formation

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    A promising approach for developing new drug delivery vehicles is by using stimuli responsive hydrogel nanoparticles. Polypeptide surfactants designed in our lab have been shown to form micellar particles of varying sizes and shapes depending on the solution salt concentration. These responsive polypeptide surfactants consist of a small charged protein domain (foldon) with three elastin-like polypeptide (ELP) chains forming a three-armed star polymer. The size and shape of the micelles they form is dependent on the ratio of total ELP volume to head group area. By introducing linear ELP into the ELP-foldon solution, the total volume of ELP in the aggregate would be increased if the linear ELP is incorporated in the micelle. This method could control the particle size and shape. To determine if the linear and three-armed ELPs co-assemble, we have observed aggregation as a function of temperature using turbidity measurements in a UV-vis spectrometer. We have found that higher concentrations of linear ELP increases the difference in transition temperature between the linear and three-armed ELP. At these higher ratios, the linear ELP aggregates prior to micelle formation. When the ELP-foldon subsequently passes through its critical micelle temperature, they break down the linear ELP aggregates resulting in smaller colloidal emulsions. Light scattering will be used to characterize the size and shape of these aggregates.https://engagedscholarship.csuohio.edu/u_poster_2013/1016/thumbnail.jp

    Controlling the Size and Shape of Polypeptide Colloidal Particles: Temperature Dependence of Particle Formation

    Get PDF
    A promising approach for developing new drug delivery vehicles is by using stimuli responsive hydrogel nanoparticles. Polypeptide surfactants designed in our lab have been shown to form micellar particles of varying sizes and shapes depending on the solution salt concentration. These responsive polypeptide surfactants consist of a small charged protein domain (foldon) with three elastin-like polypeptide (ELP) chains forming a three-armed star polymer. The size and shape of the micelles they form is dependent on the ratio of total ELP volume to head group area. By introducing linear ELP into the ELP-foldon solution, the total volume of ELP in the aggregate would be increased if the linear ELP is incorporated in the micelle. This method could control the particle size and shape. To determine if the linear and three-armed ELPs co-assemble, we have observed aggregation as a function of temperature using turbidity measurements in a UV-vis spectrometer. We have found that higher concentrations of linear ELP increases the difference in transition temperature between the linear and three-armed ELP. At these higher ratios, the linear ELP aggregates prior to micelle formation. When the ELP-foldon subsequently passes through its critical micelle temperature, they break down the linear ELP aggregates resulting in smaller colloidal emulsions. Light scattering will be used to characterize the size and shape of these aggregates.https://engagedscholarship.csuohio.edu/u_poster_2013/1016/thumbnail.jp
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