Matrix tablet: a review

In order to achieve the therapeutic purpose, the choice of the most suitable delivery route is of indisputable importance. Therefore, certain factors must be taken into consideration when delivering a active substance, namely its own properties, the disease to be diagnosed and the desired beneficial time. The active substances can be directly to the target tissue or organ or can be delivered by systemic routes

UTILIZATION OF LIBRARY INFORMATION SOURCES AND SERVICES IN THE ENGINEERING COLLEGES: A CASE STUDY

The academic libraries are the Heart of any institution. The usage of information sources and services of users is vital for academic library collections, services and facilities to meet their information needs effectively. This paper studies the usage of information sources and services of Engineering college libraries, Secunderabad. For the purpose of the study a questionnaire was distributed to find out information seeking behavior and know the whether the engineering faculty get the services offered by the library staff and the way of obtaining relevant information, and discover the problems facing when seeking for information and determine the suggestions while they are seeking information at engineering college Libraries

Nanostructured ZnO-Based Electrochemical Sensor with Anionic Surfactant for the Electroanalysis of Trimethoprim

In this research, detection of trimethoprim (TMP) was carried out using a nanostructured zinc oxide nanoparticle-modified carbon paste electrode (ZnO/CPE) with an anionic surfactant and sodium dodecyl sulphate (SDS) with the help of voltametric techniques. The electrochemical nature of TMP was studied in 0.2 M pH 3.0 phosphate-buffer solution (PBS). The developed electrode displayed the highest peak current compared to nascent CPE. Effects of variation in different parameters, such as pH, immersion time, scan rate, and concentration, were investigated. The electrode process of TMP was irreversible and diffusion controlled with two electrons transferred. The effective concentration range (8.0 × 10−7 M–1.0 × 10−5 M) of TMP was obtained by varying the concentration with a lower limit of detection obtained to be 2.58 × 10−8 M. In addition, this approach was effectively employed in the detection of TMP in pharmaceutical dosages and samples of urine with the excellent recovery data, suggesting the potency of the developed electrode in clinical and pharmaceutical sample analysis

An Electrochemical Electrode to Detect Theophylline Based on Copper Oxide Nanoparticles Composited with Graphene Oxide

The electrochemical analysis of theophylline (THP) was investigated by fabricating a carbon paste electrode (CPE) modified with graphene oxide (GO) along with copper oxide (CuO) nanoparticles (CuO-GO/CPE). The impact of electro-kinetic parameters such as the heterogeneous rate constant, the scan rate, the accumulation time, the pH, the transfer coefficient, and the number of electrons and protons transferred into the electro-oxidation mechanism of THP has been studied utilizing electrochemical methods such as cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The differential pulse voltammetry technique was employed to investigate THP in pharmaceutical and biological samples, confirming the limit of detection (LOD) and quantification (LOQ) of the THP. X-ray diffraction (XRD) and scanning electron microscopy (SEM) analysis were performed to characterize the CuO nanoparticles. The CuO-GO/CPE was more sensitive in THP detection because its electrocatalytic characteristics displayed an enhanced peak current in the 0.2 M supporting electrolyte of pH 6.0, proving the excellent sensing functioning of the modified electrode