11 research outputs found

    The relationship between level of hope and level of coping response of single parents in selected barangays in Dasmarinas Bagong Bayan, Bayan

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    Descriptive-correlation design was used to determine the relationship between level of hope and level of coping response of single parents in selected Barangays in Area DBB. A total of 150 respondents were selected using purposive non-quota sampling. A questionnaire type of survey was adapted from the instrument used in the study of Dr. Herth to obtain the information on the level of hope of single parent. Statistical measures used were mean, standard deviation, Analysis of Variance (ANOVA), independen T-test and Pearson’s r or Pearson’s Correlation Coefficient. Based on the findings, the following conclusions were drawn: (1) Majority of the single parents were female, 40 years old and above, elementary graduate, had a monthly family income of above P20,000, and non-Catholic; (2) The overall mean on the level of hope of all respondents was 2.47 interpreted as low level of hope; (3) The proactive and avoidance coping had a mean score of 2.48 and 2.43, respectively, which were verbally interpreted as coping response to a limited extent (CRLE). The reflective coping had a mean score of 2.63, preventive coping had a mean score of 2.55, instrumental coping had a mean score of 2.60, emotional coping had a mean score of 2.58, and strategic coping had a mean score 2.58 which were verbally interpreted as coping response to a moderate extent (CRME

    Efficacy and tolerability of Menorest 50 compared with Estraderm TTS 50 in the treatment of postmenopausal symptoms. A randomized, multicenter, parallel group study.

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    Two-hundred and five (205) menopausal women with moderate to severe vasomotor symptoms, aged 39-64 years, were randomized from 20 clinical centers. After a 4-week treatment-free period, each woman received a cyclical regimen (25 days of a 4-week cycle) of Menorest 50, a new matrix-type transdermal estradiol system or Estraderm TTS 50, a marketed reservoir-type transdermal estradiol system twice weekly for 12 weeks. An oral progestin was also given for 10 days each cycle. The objectives were to compare local and systemic tolerability and efficacy in the treatment of menopausal symptoms. One-hundred and ninety-four [194] patients (96 and 98 patients in the Menorest 50 and the reservoir transdermal patch groups, respectively) were considered in the intent-to-treat population and 204 (102 in each group) in the safety population. The two treatment groups were comparable with regard to the demographic data and menopausal status. The primary efficacy criteria were the comparison between Menorest 50 and the reservoir transdermal patch in erythema and pruritus at application sites and the difference between the treatment groups in the mean number of hot flushes per day at week 12, adjusted for baseline. A statistically significant reduction in the mean number of hot flushes was observed in each group compared with baseline, with a decrease from 6.5 at baseline to 0.3 at 12 weeks and 6.4 to 0.4 in the Menorest 50 and reservoir transdermal patch groups respectively; there was no statistically significant difference between the two groups during the 12-week treatment. The severity score of menopausal symptoms was also dramatically improved in each of the two treatment groups. There were no statistically significant differences in the mean plasma estradiol concentrations and mean estradiol to estrone ratio (> 1.0) in both groups after 10 weeks of therapy. A similar number of adverse events was observed in both groups. Menorest 50 showed better local tolerability than the reservoir transdermal patch with a lower incidence of topical adverse events, erythema and pruritus. In summary, Menorest 50 was as effective as the reservoir transdermal patch in reducing the mean number of hot flushes, and improving the severity of other menopausal symptoms, including vasomotor, psychiatric and urogenital symptoms
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