Simple threshold rules solve explore/exploit trade‐offs in a resource accumulation search task

How, and how well, do people switch between exploration and exploitation to search for and accumulate resources? We study the decision processes underlying such exploration/exploitation trade‐offs using a novel card selection task that captures the common situation of searching among multiple resources (e.g., jobs) that can be exploited without depleting. With experience, participants learn to switch appropriately between exploration and exploitation and approach optimal performance. We model participants' behavior on this task with random, threshold, and sampling strategies, and find that a linear decreasing threshold rule best fits participants' results. Further evidence that participants use decreasing threshold‐based strategies comes from reaction time differences between exploration and exploitation; however, participants themselves report non‐decreasing thresholds. Decreasing threshold strategies that “front‐load” exploration and switch quickly to exploitation are particularly effective in resource accumulation tasks, in contrast to optimal stopping problems like the Secretary Problem requiring longer exploration

Avalanches in a Bose-Einstein condensate

Collisional avalanches are identified to be responsible for an 8-fold increase of the initial loss rate of a large 87-Rb condensate. We show that the collisional opacity of an ultra-cold gas exhibits a critical value. When exceeded, losses due to inelastic collisions are substantially enhanced. Under these circumstances, reaching the hydrodynamic regime in conventional BEC experiments is highly questionable.Comment: 4 pages, 2 figures, 1 tabl

Six degrees of freedom vibration isolation using electromagnetic suspension

Experimental data are presented for modeling an electromagnet. Control laws are considered with and without flux feedback and with position and orientation information of the suspended body. Base motion and sensor noise are the principal disturbances. Proper selection of the geometrical operating point minimizes the passive coupling above the bandwidth of the control and filtering can attenuate the high frequency content of sensor noise. Six electromagnets are arranged in a configuration which optimizes the load support and provides control over all six degrees of freedom of the suspended body. The design is based on experimental data generated with a specially designed test facility. Application for suspension of a gravity wave antenna is discussed

Time-Resolved Intraband Relaxation of Strongly-Confined Electrons and Holes in Colloidal PbSe Nanocrystals

The relaxation of strongly-confined electrons and holes between 1P and 1S levels in colloidal PbSe nanocrystals has been time-resolved using femtosecond transient absorption spectroscopy. In contrast to II-VI and III-V semiconductor nanocrystals, both electrons and holes are strongly confined in PbSe nanocrystals. Despite the large electron and hole energy level spacings (at least 12 times the optical phonon energy), we consistently observe picosecond time-scale relaxation. Existing theories of carrier relaxation cannot account for these experimental results. Mechanisms that could possibly circumvent the phonon bottleneck in IV-VI quantum dots are discussed

The Significance of Powder Breakdown During Conveying Within Industrial Milk Powder Plants

Instant whole milk powder (IWMP) is designed to rapidly dissolve in water, which depends on the particle size distribution (PSD). The fragile milk powder exiting the dryer has to be conveyed for packing, which can break down the particles, worsening the dissolution properties. This work investigated the importance of in-plant conveying in determining the nal functional properties at the industrial scale. IWMP breakdown was compared between two plants with di erent transport systems; a pneumatic system and bucket elevator. It was expected that the plant with the bucket elevator consistently produced powder with superior dissolution due to lower breakdown during transport. This was evaluated using the change in PSD. It was found that both plants had a similar decrease in the median particle size, and powder with an initially larger particle size showed more breakdown. However, it was not enough to compensate for the initially larger size. Thus powder that started out larger still had a larger particle size after transport. When quanti ed using the change in bulk density, a low initial bulk density compensated for large breakdown during conveying and ameliorated the impact on the functional properties. Thus in order to produce IWMP with the desired functionalities the focus should be on improving the initial agglomeration, as oppose to reducing transport breakdown.

Prolyl-peptidyl isomerase, Pin1, phosphorylation is compromised in association with the expression of the HFE polymorphic allele, H63D

AbstractThere is substantial interest in HFE gene variants as putative risk factors in neurodegenerative diseases such as Alzheimer disease (AD). Previous studies in cell models have shown the H63D HFE variant to result in increased cellular iron, oxidative stress, glutamate dyshomeostasis, and an increase in tau phosphorylation; all processes thought to contribute to AD pathology. Pin1 is a prolyl-peptidyl cis/trans isomerase that can regulate the dephosphorylation of the amyloid and tau proteins. Hyperphosphorylation of these later proteins is implicated in the pathogenesis of AD and Pin1 levels are reportedly decreased in AD brains. Because of the relationship between Pin1 loss of function by oxidative stress and the increase in oxidative stress in cells with the H63D polymorphism it was logical to interrogate a relationship between Pin1 and HFE status. To test our hypothesis that H63D HFE would be associated with less Pin1 activity, we utilized stably transfected human neuroblastoma SH-SY5Y cell lines expressing the different HFE polymorphisms. Under resting conditions, total Pin1 levels were unchanged between the wild type and H63D HFE cells, yet there was a significant increase in phosphorylation of Pin1 at its serine 16 residue suggesting a loss of Pin1 activity in H63D variant cells. To evaluate whether cellular iron status could influence Pin1, we treated the WT HFE cells with exogenous iron and found that Pin1 phosphorylation increased with increasing levels of iron. Iron exposure to H63D variant cells did not impact Pin1 phosphorylation beyond that already seen suggesting a ceiling effect. Because HFE H63D cells have been shown to have more oxidative stress, the cells were treated with the antioxidant Trolox which resulted in a decrease in Pin1 phosphorylation in H63D cells with no change in WT HFE cells. In a mouse model carrying the mouse equivalent of the H63D allele, there was an increase in the phosphorylation status of Pin1 providing in vivo evidence for our findings in the cell culture model. Thus, we have shown another cellular mechanism that HFE polymorphisms influence; further supporting their role as neurodegenerative disease modifiers

Composite-fermion crystallites in quantum dots

The correlations in the ground state of interacting electrons in a two-dimensional quantum dot in a high magnetic field are known to undergo a qualitative change from liquid-like to crystal-like as the total angular momentum becomes large. We show that the composite-fermion theory provides an excellent account of the states in both regimes. The quantum mechanical formation of composite fermions with a large number of attached vortices automatically generates omposite fermion crystallites in finite quantum dots.Comment: 5 pages, 3 figure