A novel SSGK to protect the communication process and shared data from unauthorized access

A cloud-based big data sharing system uses a storage facility from a cloud specialist co-op to impart data to authentic clients. As opposed to customary arrangements, cloud supplier stores the mutual data in the huge server farms outside the trust area of the data proprietor, which may trigger the issue of data classification. This paper proposes a secret sharing group key management convention (SSGK) to secure the correspondence procedure and shared data from unapproved get to. Not quite the same as the earlier works, a shared key is utilized to encode the common data and a secret sharing plan is utilized to circulate the shared key in SSGK. The broad security and execution investigations demonstrate that our convention profoundly limits the security and protection dangers of sharing data in distributed storage and spares about 12% of extra storage space

Cerimetric Titration of As(III) in Acetic Acid Medium

369-37

Hepatoprotective and antioxidant capacity of Melochia corchorifolia extracts

AbstractObjectiveTo evaluate hepato protective and antioxidant capacity of Melochia corchorifolia (M. corchorifolia) aerial part extracts.MethodsAntioxidant activity was evaluated by using three free radicals (Superoxide, Hydroxyl and DPPH) and hepatoprotective activity was assessed against CCl4 induced liver intoxication in rats.ResultsThe extracts produced concentration dependent percentage protection in decrease of serum enzymes and percentage inhibition on free radicals. Among all extracts methanol extract showed better activity with percentage protection of SGOT (78.98%), SGPT (79.65%), ALP (82.48%) and total bilirubin (80.0%) levels against CCl4 liver intoxication and also methanolic extract showed better activity with IC50 values on superoxide, hydroxyl and DPPH radicals were 127 μ g, 240 μ g and 179 μ g.ConclusionsFrom the results obtained during the study it could be concluded that M. corchorifolia aerial part extracts have antioxidant and hepatoprotective components. Further study is necessary for isolation and characterization of bioactive molecules which are responsible for hepatoprotective and antioxidant activity

FORMULATION AND DEVELOPMENT OF MULTILAYER AND MONOLITHIC EXTENDED RELEASE MATRIX TABLETS OF ALFUZOSIN HCL

Objective: In present investigation an attempt has been made to increase therapeutic efficacy, reduce frequency of administration and improve patient compliance, by developing extended release monolithic and multilayered tablets of Alfuzosin hydrochloride. Methods: Extended release matrix tablets of Alfuzosin were developed by using different drug and polymer ratio with guar gum, Hydroxypropylmethylcellulose, xanthan gum as matrix formers. All lubricated formulations were compressed by wet granulation method. Results: Compressed tablets were evaluated for uniformity of weight, content of active ingredient, friability, hardness, thickness, invitro dissolution. All the formulation showed compliance with Pharmacopoeial standards. In vitro release studies indicated that matrix multilayer tablets prepared by wet granulation with various proportions of polymer mixtures failed to control the drug release for extended period of time. Controlled delivery of Alfuzosin could be achieved in  F8, F9 and to a lesser extent F7 tablet formulations which released  67percent, 86percent,and 90percent of drug, respectively, at the end of 20th hr in 0.01N HCl. Conclusion: Among these monolithic matrix tablets F9 prepared with guar gum-HPMC-xanthan gum mixture in 1ration11ration4  shown comparable drug release profiles at 1st and 20th h as 18percent and 86percent as that of the innovator Xatral Drug release kinetics indicated that drug release was best explained by Higuchi as these plots showed the highest linearity  r x r = 0.9979. Keywords:  Alfuzosin, matrix multilayer, xanthan gum, Methocel, extended release.Â&nbsp

Real Time Evaluation of Tissue Optical Properties during Thermal Ablation of \u3cem\u3eex vivo\u3c/em\u3e Liver Tissues

Complete ablation of liver tumors is vital for minimizing the risk of local tumor recurrence. Accurately identifying the hallmarks of tissue necrosis during thermal ablative therapies may significantly increase the efficacy of ablation, while minimizing unnecessary damage to the surrounding normal tissues or critical structures. Light propagation in biological tissues is sensitive to the tissue microstructure and chromophore concentrations. In our previous studies, we found that the wavelength (λ) averaged liver tissue absorption coefficient μa and reduced scattering coefficient μs’ change significantly upon heating which may be used for assessment of tissue damage during thermal ablation of solid tumors. Here, we seek to demonstrate the use of an integrated fiber-optic probe for continuous monitoring of the local tissue temperature (T), μa(λ) and μs’(λ) during thermal ablation of ex vivo porcine livers. The wavelength-averaged (435–630 nm) tissue absorption and scattering (μa and μs’) increased rapidly at 45 °C and plateaued at 67 °C. The mean μa and μs’ for liver tissue at 37 °C (n = 10) were 8.5 ± 3.7 and 2.8 ± 1.1 cm−1, respectively. The relative changes in μa and μs’ at 37, 55, and 65 °C were significantly different (p \u3c .02) from each other. A relationship between the relative changes in μa and μs’ and the degree of tissue damage estimated using the temperature-based Arrhenius model for porcine liver tissues was established and studied

Unravelling Seasonal Shifts: Exploring Carbon and Nitrogen Stable Isotope Signatures in Zooplankton of Kakinada Bay, Andhra Pradesh, India.

The present study focused on the seasonal variability of carbon and nitrogen stable isotopic signatures in zooplankton collected from Kakinada Bay. Physiochemical parameters of the bay, such as temperature, salinity, nitrates, nitrites, dissolved nutrients, phosphates, and chlorophyll a, were evaluated. The isotopic ratios of carbon and nitrogen in zooplankton and POM were determined using an isotope-ratio mass spectrophotometer. The δ13C values of zooplankton and POM were higher in Kakinada Bay, indicating enrichment of δ13C in primary production. The δ15N values of zooplankton ranged from 8.17 to 9.58, with the highest values observed during the monsoon season. The study provides insights into the trophic structure and anthropogenic influences on the marine ecosystem in Kakinada Ba

Qualitative and quantitative phytochemical screening and in vitro anti oxidant and anti microbial activities of Elephantopus scaber Linn.

Preliminary phytochemical analysis and quantification of total phenols, In-vitro antioxidant and anti microbial activities of the different fractions (hydro alcoholic, hexane, ethyl acetate and methanol) of Elephantopus scaber were carried out against five selected pathogenic bacteria and three fungal species. The plant fraction possesses steroids, triterpinoids, saponins, flavonoides, carbohydrates, glycosides and oils. For total phenolic content gallic acid was taken as a standard, the ethyl acetate fraction contains rich phenolic content than other fractions and the methanol fraction shows more DPPH, superoxide and hydroxyl radical scavenging activity. In Anti-microbial activity study all fractions showed good inhibition zone against three organisms i.e., Escherichia coli, Staphylococcus aureus Klebsiella pneumonia among the other test organisms along with Candida spp (fungal organism)