18,213 research outputs found

    Keeping Up with the Joneses: New Models to Support Developing Needs

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    The purpose of this paper is to explore models that may improve interdisciplinary collection strategies. Practical alternatives and expansions to existing services that can be explored without the burden of irreversible consequences will be discussed. This paper is intended more so as a conversation starter about altering our thought processes in regards to how librarians carry out their work to meet new demands. It is not intended to be a guide with proven methods that will work universally. These proposals are set within the context of a library that is part of a large research institution.International Federation of Library AssociationsUniversity of Toronto, LibraryUniversity of Toronto, Faculty of InformationUniversity of Illinois, LibraryTitle VI National Resource Center Grant (P015A060066)unpublishednot peer reviewe

    The leafage of a chordal graph

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    The leafage l(G) of a chordal graph G is the minimum number of leaves of a tree in which G has an intersection representation by subtrees. We obtain upper and lower bounds on l(G) and compute it on special classes. The maximum of l(G) on n-vertex graphs is n - lg n - (1/2) lg lg n + O(1). The proper leafage l*(G) is the minimum number of leaves when no subtree may contain another; we obtain upper and lower bounds on l*(G). Leafage equals proper leafage on claw-free chordal graphs. We use asteroidal sets and structural properties of chordal graphs.Comment: 19 pages, 3 figure

    Pathology in Practice

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    Patient acceptability, safety and access : A balancing act for selecting age-appropriate oral dosage forms for paediatric and geriatric populations

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    © 2017 Elsevier B.V. All rights reserved.The selection and design of age-appropriate formulations intended for use in paediatric and geriatric patients are dependent on multiple factors affecting patient acceptability, safety and access. The development of an economic and effective product relies on a balanced consideration of the risks and benefits of these factors. This review provides a comprehensive and up-to-date analysis of oral dosage forms considering key aspects of formulation design including dosage considerations, ease of use, tolerability and safety, manufacturing complexity, stability, supply and cost. Patient acceptability has been examined utilising an evidence-based approach to evaluate regulatory guidance and literature. Safety considerations including excipients and potential risk of administration errors of the different dosage forms are also discussed, together with possible manufacturing and supply challenges. Age appropriate drug product design should consider and compare i) acceptability ii) safety and iii) access, although it is important to recognise that these factors must be balanced against each other, and in some situations a compromise may need to be reached when selecting an age-appropriate formulation.Peer reviewedFinal Accepted Versio

    ECONOMIC IMPACTS OF BANNING SUBTHERAPEUTIC USE OF ANTIBIOTICS IN SWINE PRODUCTION

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    Public health officials and physicians are concerned about possible development of bacterial resistance and potential effects on human health that may be related to the use of antimicrobial agents in livestock feed. The focus of this research is aimed at determining the economic effects that subtherapeutic bans of antimicrobials would have on both swine producers and consumers. The results show that a ban on growth promotants for swine would be costly, totaling 242.5millionannuallywithswineproducerssharingthelargerportionintheshortrunandconsumerssharingabout75242.5 million annually with swine producers sharing the larger portion in the short run and consumers sharing about 75% in the long run. If a ban affected poultry as well as pork production, the total costs would expand to 586 million per year with swine producers sharing about the same as in bans for swine only and consumers sharing significantly more than the swine only case.Crop Production/Industries,

    A very high frequency radio interferometer for investigating ionospheric disturbances using geostationary satellites. Determination of changes in exospheric electron content by a comparison of group delay and Faraday rotation

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    The theory and development of a VHF correlation radio interferometer for investigating ionospheric disturbances are discussed. The system was developed to receive signals from the geostationary Applications Technology Satellites. Amplitude and phase variations of the signal passing through the ionosphere can be detected by this instrument. The system consists of two superheterodyne receivers separated by a distance known as the baseline of the system. Since the system is a phase sensitive instrument, the local oscillators of the two receivers must be phase coherent. This is accomplished by using phase-locked loops for generating the local oscillators. The two signals from the separate receivers are cross-correlated by multiplying the two signals together and then time averaging the result. The sensitivity of the instrument is increased by off-setting one of the local oscillators by a small amount

    A Fusion Hybrid Propulsion System for Rapid Interplanetary Transport

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90718/1/AIAA-2011-6117-851.pd

    Damages Assessed Against Insurers for Wrongful Failure to Pay

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