Straight versus S-shaped sternotomy: a histologic study in the sheep model

INTRODUCTION: Straight sternotomy is the most common access for open heart surgery. Techniques have been proposed for maximizing sternal stability in high-risk patients. This trend implies a growing need for newer surgical techniques. The aim of this experimental study in the sheep model is to evaluate median vs. S shaped sternotomy the feasibility of using a special device to accelerate the sternal instability and bone healing. MATERIALS AND METHODS: We enrolled 31 sheep, weighing 18–30 kg. For all animals a midline skin incision was made. In group I (n = 16 animals), straight median sternotomy and in group II (n = 15 animals), S-shaped incision was marked on the periosteum of the sternum by new created device for standard S-shaped sternotomy. Sternum biopsies were performed on second surgery month for all survived animals from the sternum and the surrounding soft tissue. RESULTS: No early superficial wound complications were observed. Overall mortality in the initial approach group was 19.3% (6 sheep). In group I; 3 sheep had died on first surgery day, the reason may be hemorrhage and in group II; 3 sheep developed intractable VF during surgery procedure or immediately afterwards so died. There were statistically significant differences in the scores of bone healing between group 1 and group 2 (4.2 vs.7.3, ANOVA, p < 0.001). DISCUSSION: Our work is based on the use of a standard S-shaped sternotomy procedure on sheep sternum. In our experience with the sternal healing in the sheep model, the process of new bone formation was accelerated with S- shaped cut than straight sternotomy procedure. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13019-014-0173-x) contains supplementary material, which is available to authorized users

Single dose regorafenib-induced hypertensive crisis

Gastrointestinal stromal tumors (GISTs) are uncommon tumors of the gastrointestinal (GI) tract. Regorafenib is a new multikinase inhibitor and is approved for the treatment of GISTs in patients who develop resistance to imatinib and sunitinib. The most common drug-related adverse events with regorafenib are hypertension, hand-foot skin reactions, and diarrhea. Grade IV hypertensive side effect has never been reported after a single dose. In this report, we present a case of Grade IV hypertensive side effect (hypertensive crisis and seizure) after a single dose of regorafenib. A 54-year-old male normotensive GIST patient was admitted to the emergency department with seizure and encephalopathy after the first dosage of regorafenib. His blood pressure was 240/140 mmHg upon admission. After intensive treatment with nitrate and nitroprusside, his blood pressure returned to normal levels in five days. Regorafenib was discontinued, and he did not experience hypertension again. This paper reports the first case of Grade IV hypertension after the first dosage of regorafenib. We can suggest that hypertension is an idiosyncratic side effect unrelated to the dosage. Key Words: hypertension, regorafenib, gastrointestinal stromal tumor

New Mediterranean Biodiversity Records (April, 2019)

The Collective Article on “New Mediterranean Biodiversity Records” offers the means to publish biodiversity records in the Mediterranean Sea. The current article presents new biodiversity data information on 18 taxa (14 alien, 3 native and 1 cryptogenic species) belonging to 5 Phyla that are reported for 11 different countries listed according to their geographic position from the western to the eastern Mediterranean Sea. Algeria: the alien green alga Caulerpa taxifolia var. distichophylla and the heterobranchs Aplysia dactylomeda and Aplysia punctata are first reported from the entire country. France: a new record of the alien hydroid Porpita porpita is reported from the Corsican Sea, representing the second record of the species in the western Mediterranean Sea. Tunisia: the alien fish Scatophagus argus is reported from the Gulf of Gabès, probably representing an aquarium release. Italy: the well-established Mediterranean alien bivalve Malleus regula is first reported from the entire country. Slovenia: the alien marine bivalve Xenostrobus securis is reported for the first time from the entire country. Croatia: the alien gastropod Biuve fulvipunctata is reported for the first time from the country but also from the entire Adriatic Sea. Montenegro: the alien bivalve Rapana venosa is reported for the first time from the Montenegrin waters. Albania: the well-established alien fish Lagocephalus sceleratus and the rare native shark Rhizoprionodon acutus are reported for the first from the entire country. Greece: the rare native ray Leucoraja circularis is reported for the first time from the Argolikos Gulf and for the first time for the entire country its identification is confirmed morphologically and molecularly; additional records of the alien nomad jellyfish Rhopilema nomadic document its expanding distribution, while the occurrence and the alien fishes Sillago suezensis and Pomadasys stridens are reported for the first time from Hellenic waters. Turkey: additional records of the Egyptian Prawn Metapenaeopsis aegyptia are reported with some biological information. Cyprus: the alien fish Variola louti is reported for the first time for the entire Mediterranean Sea, probably released from an aquarium, while the alien moon crab Matuta victor is reported for the first time from the entire country

The evelotion of lifting and moving with vacuming systems effects on public health

Bu çalışma, 04-05, Haziran 2015 tarihlerinde İstanbul[Türkiye]’de düzenlenen Global Business Research Congress (GBRC) Kongresi‘nde bildiri olarak sunulmuştur.Workers are applying momentum and power which different duration and time in their working area. There are differences between workers, cause ofsex, a ge, health s tatus, e xperience, disabling. Also s ettling of w orks effects the l imits of p ower a nd m omentum w hich applied. There are a lot of different accounting method which obtained reserch and experience to determine power and momentum applied by workers. In this study it was analaysed weight on workers who works in lift and movement job with vacuming systems. Rubber goods between 9 and 25 kg weight were moved from container to conveyor in this study. 150 pcs rubber good which is different weight and size has moved every day by a worker who employed on this job. Analaysis by REBA method and ergonomic risk evalaution has done depend on Assessment Methods of Occupational Safety and Occupational Medicine Institutions of Germany. By the studies has contributed to reducing the disease ofmusculoskeletal system in the health management

Ergonomic analysis of working postures that cause strain on workers that work in hand placement business of transporting containers

Bu çalışma, 04-05, Hazziran 2015 tarihlerinde Istanbul[Türkiye]’de düzenlenen Global Business Research Congress (GBRC) Kongresi‘nde bildiri olarak sunulmuştur.Due to increased competition in the globalized world, technological innovations and higher production rates have become very important for businesses. Despite advances and innovations in technology, the employees who work in countries which have developed industry resulting musculoskeletal disorders causes serious economic losses, it has been shown to affect the entire community rather than individuals in it. Reducing the fatigue and stress consists physical overloading on human provides significant contributions on productivity and labor costs. To be understanding of this situation emerges the i mportance of working stance. Today has started to benefit from t he ergonomic analysis for the elimination of all actions and activities that do not contribute to production. Poor posture is observed during the some works such as hand placement business of transporting containers. For study of analysis, these works are selected and the methods of REBA and BAUA are benefited to investigate the posture of employees during work. BAUA analysis method cares about all body posture, carried load and time of carrying but REBA analysis method considers also the score of stance of upper limb. In this study, REBA and BAUA ergonomic analysis methods are evaluated by comparing to learn what the results are in a predetermined proces