Suppression of Richtmyer-Meshkov instability via special pairs of shocks and phase transitions

The classical Richtmyer-Meshkov instability is a hydrodynamic instability characterizing the evolution of an interface following shock loading. In contrast to other hydrodynamic instabilities such as Rayleigh-Taylor, it is known for being unconditionally unstable: regardless of the direction of shock passage, any deviations from a flat interface will be amplified. In this article, we show that for negative Atwood numbers, there exist special sequences of shocks which result in a nearly perfectly suppressed instability growth. We demonstrate this principle computationally and experimentally with stepped fliers and phase transition materials. A fascinating immediate corollary is that in specific instances a phase transitioning material may self-suppress RMI

Telehealth for patients with Parkinson\u27s disease: delivering efficient and sustainable long-term care.

OBJECTIVES: We set out to demonstrate the benefits of providing long-term care via telehealth for patients with Parkinson\u27s disease living in continuous care facilities. METHODS: A cohort of 16 patients with Parkinson\u27s disease residing at one of 2 locations of a multi-facility continuous care retirement organization were seen virtually in follow-up over a 3-year period by Telehealth Services at a large, academic, tertiary care hospital in southeastern Pennsylvania. The data collected during that period, studied retrospectively, included demographic information, number of telehealth visits, and UPDRS scores obtained at each visit. Satisfaction and potential cost savings were also reviewed. RESULTS: UPDRS scores declined over the period of observation, from a range of 18-60 at study start to 28-72 at study end. Actual cost savings are difficult to define; however, the cost per telehealth visit at $117.30 was often lower than the facility\u27s average cost for transporting patients to a visit in the neurologist\u27s office. Patients, families, subspecialists, and the nursing staff expressed uniformly high satisfaction with telehealth. CONCLUSION: This model for providing care proved to be sustainable and efficient, and promoted collaboration among the providers at the long-term care facility and those at the remote site. These benefits may be applicable to patients with degenerative disorders in similar settings

Bombyx mori Nucleopolyhedrovirus Displaying Neospora caninum Antigens as a Vaccine Candidate Against N. caninum Infection in Mice

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