Study of the scientific potential of a three 40 cm Telescopes Interferometer at Dome C

Recent site testing (see: http://www-luan.unice.fr/Concordiastro/indexantartic.html) has shown that Dome C in Antarctica might have a high potential for stellar interferometry if some solutions related to the surface atmospheric layer are found. A demonstrator interferometer could be envisioned in order to fully qualify the site and prepare the future development of a large array. We analyse the performances of a prototype interferometer for Dome C made with 3 telescopes of 40 cm diameter. It assumes classical Michelson recombination. The most recent atmospheric and environmental conditions measured at Dome C are considered (see K. Agabi "First whole atmosphere night-time seeing measurements at Dome C, Antarctica"). We also study the possible science reachable with such a demonstrator. Especially we evaluate that even such small aperture interferometer could allow the detection and low resolution spectroscopy of the most favourable pegaside planets.Comment: 6 pages, 5 figures, conferences SPIE, 0rlando, 200

Photometric quality of Dome C for the winter 2008 from ASTEP South

ASTEP South is an Antarctic Search for Transiting Exo- Planets in the South pole field, from the Concordia station, Dome C, Antarctica. The instrument consists of a thermalized 10 cm refractor observing a fixed 3.88\degree x 3.88\degree field of view to perform photometry of several thousand stars at visible wavelengths (700-900 nm). The first winter campaign in 2008 led to the retrieval of nearly 1600 hours of data. We derive the fraction of photometric nights by measuring the number of detectable stars in the field. The method is sensitive to the presence of small cirrus clouds which are invisible to the naked eye. The fraction of night-time for which at least 50% of the stars are detected is 74% from June to September 2008. Most of the lost time (18.5% out of 26%) is due to periods of bad weather conditions lasting for a few days ("white outs"). Extended periods of clear weather exist. For example, between July 10 and August 10, 2008, the total fraction of time (day+night) for which photometric observations were possible was 60%. This confirms the very high quality of Dome C for nearly continuous photometric observations during the Antarctic winter

Possible detection of phase changes from the non-transiting planet HD 46375b by CoRoT

The present work deals with the detection of phase changes in an exoplanetary system. HD 46375 is a solar analog known to host a non-transiting Saturn-mass exoplanet with a 3.0236 day period. It was observed by the CoRoT satellite for 34 days during the fall of 2008. We attempt to identify at optical wavelengths, the changing phases of the planet as it orbits its star. We then try to improve the star model by means of a seismic analysis of the same light curve and the use of ground-based spectropolarimetric observations. The data analysis relies on the Fourier spectrum and the folding of the time series. We find evidence of a sinusoidal signal compatible in terms of both amplitude and phase with light reflected by the planet. Its relative amplitude is Delta Fp/F* = [13.0, 26.8] ppm, implying an albedo A=[0.16, 0.33] or a dayside visible brightness temperature Tb ~ [1880,2030] K by assuming a radius R=1.1 R_Jup and an inclination i=45 deg. Its orbital phase differs from that of the radial-velocity signal by at most 2 sigma_RV. However, the tiny planetary signal is strongly blended by another signal, which we attribute to a telluric signal with a 1 day period. We show that this signal is suppressed, but not eliminated, when using the time series for HD 46179 from the same CoRoT run as a reference. This detection of reflected light from a non-transiting planet should be confirmable with a longer CoRoT observation of the same field. In any case, it demonstrates that non-transiting planets can be characterized using ultra-precise photometric lightcurves with present-day observations by CoRoT and Kepler. The combined detection of solar-type oscillations on the same targets (Gaulme et al. 2010a) highlights the overlap between exoplanetary science and asteroseismology and shows the high potential of a mission such as Plato.Comment: 4 pages, 6 figure

ASTEP South: An Antarctic Search for Transiting ExoPlanets around the celestial South pole

ASTEP South is the first phase of the ASTEP project (Antarctic Search for Transiting ExoPlanets). The instrument is a fixed 10 cm refractor with a 4kx4k CCD camera in a thermalized box, pointing continuously a 3.88 degree x 3.88 degree field of view centered on the celestial South pole. ASTEP South became fully functional in June 2008 and obtained 1592 hours of data during the 2008 Antarctic winter. The data are of good quality but the analysis has to account for changes in the point spread function due to rapid ground seeing variations and instrumental effects. The pointing direction is stable within 10 arcseconds on a daily timescale and drifts by only 34 arcseconds in 50 days. A truly continuous photometry of bright stars is possible in June (the noon sky background peaks at a magnitude R=15 arcsec-2 on June 22), but becomes challenging in July (the noon sky background magnitude is R=12.5 arcsec?2 on July 20). The weather conditions are estimated from the number of stars detected in the field. For the 2008 winter, the statistics are between 56.3 % and 68.4 % of excellent weather, 17.9 % to 30 % of veiled weather and 13.7 % of bad weather. Using these results in a probabilistic analysis of transit detection, we show that the detection efficiency of transiting exoplanets in one given field is improved at Dome C compared to a temperate site such as La Silla. For example we estimate that a year-long campaign of 10 cm refractor could reach an efficiency of 69 % at Dome C versus 45 % at La Silla for detecting 2-day period giant planets around target stars from magnitude 10 to 15. This shows the high potential of Dome C for photometry and future planet discoveries. [Short abstract

The secondary eclipses of WASP-19b as seen by the ASTEP 400 telescope from Antarctica

The ASTEP (Antarctica Search for Transiting ExoPlanets) program was originally aimed at probing the quality of the Dome C, Antarctica for the discovery and characterization of exoplanets by photometry. In the first year of operation of the 40 cm ASTEP 400 telescope (austral winter 2010), we targeted the known transiting planet WASP-19b in order to try to detect its secondary transits in the visible. This is made possible by the excellent sub-millimagnitude precision of the binned data. The WASP-19 system was observed during 24 nights in May 2010. The photometric variability level due to starspots is about 1.8% (peak-to-peak), in line with the SuperWASP data from 2007 (1.4%) and larger than in 2008 (0.07%). We find a rotation period of WASP-19 of 10.7 +/- 0.5 days, in agreement with the SuperWASP determination of 10.5 +/- 0.2 days. Theoretical models show that this can only be explained if tidal dissipation in the star is weak, i.e. the tidal dissipation factor Q'star > 3.10^7. Separately, we find evidence for a secondary eclipse of depth 390 +/- 190 ppm with a 2.0 sigma significance, a phase consistent with a circular orbit and a 3% false positive probability. Given the wavelength range of the observations (420 to 950 nm), the secondary transit depth translates into a day side brightness temperature of 2690(-220/+150) K, in line with measurements in the z' and K bands. The day side emission observed in the visible could be due either to thermal emission of an extremely hot day side with very little redistribution of heat to the night side, or to direct reflection of stellar light with a maximum geometrical albedo Ag=0.27 +/- 0.13. We also report a low-frequency oscillation well in phase at the planet orbital period, but with a lower-limit amplitude that could not be attributed to the planet phase alone, and possibly contaminated with residual lightcurve trends.Comment: Accepted for publication in Astronomy and Astrophysics, 13 pages, 13 figure

Thioredoxin Interacting Protein Is Required for a Chronic Energy-Rich Diet to Promote Intestinal Fructose Absorption

Increased consumption of fats and added sugars has been associated with an increase in metabolic syndromes. Here we show that mice chronically fed an energy-rich diet (ERD) with high fat and moderate sucrose have enhanced the absorption of a gastrointestinal fructose load, and this required expression of the arrestin domain protein Txnip in the intestinal epithelial cells. ERD feeding induced gene and protein expression of Glut5, and this required the expression of Txnip. Furthermore, Txnip interacted with Rab11a, a small GTPase that facilitates the apical localization of Glut5. We also demonstrate that ERD promoted Txnip/Glut5 complexes in the apical intestinal epithelial cell. Our findings demonstrate that ERD facilitates fructose absorption through a Txnip-dependent mechanism in the intestinal epithelial cell, suggesting that increased fructose absorption could potentially provide a mechanism for worsening of metabolic syndromes in the setting of a chronic ERD

Antidepressant-Warfarin Interaction and Associated Gastrointestinal Bleeding Risk in a Case-Control Study

Bleeding is the most common and worrisome adverse effect of warfarin therapy. One of the factors that might increase bleeding risk is initiation of interacting drugs that potentiate warfarin. We sought to evaluate whether initiation of an antidepressant increases the risk of hospitalization for gastrointestinal bleeding in warfarin users.Medicaid claims data (1999-2005) were used to perform an observational case-control study nested within person-time exposed to warfarin in those ≥18 years. In total, 430,455 warfarin users contributed 407,370 person-years of warfarin use. The incidence rate of hospitalization for GI bleeding among warfarin users was 4.48 per 100 person-years (95% CI, 4.42-4.55). Each gastrointestinal bleeding cases was matched to 50 controls based on index date and state. Warfarin users had an increased odds ratio of gastrointestinal bleeding upon initiation of citalopram (OR = 1.73 [95% CI, 1.25-2.38]), fluoxetine (OR = 1.63 [95% CI, 1.11-2.38]), paroxetine (OR = 1.64 [95% CI, 1.27-2.12]), amitriptyline (OR = 1.47 [95% CI, 1.02-2.11]). Also mirtazapine, which is not believed to interact with warfarin, increased the risk of GI bleeding (OR = 1.75 [95% CI, 1.30-2.35]).Warfarin users who initiated citalopram, fluoxetine, paroxetine, amitriptyline, or mirtazapine had an increased risk of hospitalization for gastrointestinal bleeding. However, the elevated risk with mirtazapine suggests that a drug-drug interaction may not have been responsible for all of the observed increased risk