Co-citation Analysis: An Overview

This article gives an overview of co-citation analysis and its applications in tracking the linkages among the intellectual works and mapping the evolutionary structure of scientific disciplines. It also focuses on the features, interface, terminology used, merits and demerits of co-citation based online database applications

SPECTROSCOPIC AND VOLUMETRIC TECHNIQUES FOR THE ESTIMATION OF IVABRADINE IMPURITY 3,3'-(PROPANE-1,3-DIYL)BIS(7,8-DIMETHOXY-1,3,4,5-TETRAHYDRO-2H-BENZO[D]AZEPIN-2-ONE)

Objective: Two simple and sensitive techniques - one spectrophotometric and one titrimetric- have been developed for the determination of 3,3'-(propane-1,3-diyl)bis(7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one) commonly known as ivabradine impurity-9 (IVA-9). Methods: The spectrophotometric method is based on the oxidation of drug impurity by excess cerium (IV) sulphate in acidic medium and the subsequent reaction of the remaining Ce(IV) with a known amount of ferrous ammonium sulphate. The resultant ferric ion is then made to react with thiocyanate in acid medium to form a brown coloured complex which is analyzed spectrophotometrically against the reagent blank. In the volumetric method, the un-reacted Ce(IV) is titrated against standard ferrous ammonium sulphate to estimate the quantity of IVA-9. Results: The colored complex showed an absorption maximum at 479 nm when measured  spectrophotometrically. The stated methods are validated statistically using the International Council for Harmonization guidelines-ICH Q2(R1) for precision and accuracy. The method showed a linear response from 0.5 to 100µg/ml with a correlation coefficient of 0.9985 Conclusion : No estimation techniques have been reported to date for the determination of this molecule. The proposed techniques may be used for the routine quantification in its pure form and also in presence of its parent drug molecule Ivabradine

Role of Information and communication technology (ICT) in agriculture and extension

Information and communication technology (ICT) aids provide up-to-date information on the market prices of commodities, inputs and consumer trends which ultimately can improve a farmer's negotiating position and their livelihood. Major aspect of ICT is that accurate information should reach the farmers at the right time to make more sustainable use of on-farm resources. Now the question arises that how this information can be disseminated to such a diverse group of the farming community. ICT is going to play greater role in agricultural extension as well as private sector agribusiness, market information and market intelligence. Here this paper review the role of ICT not only in providing greater awareness and knowledge in agriculture technology and information but also in terms of farmer’s attitudes towards trying to adopt new technologies

STUDY OF RADON AND THORON CONCENTRATION IN ENVIRONMENT OF MORADABAD DISTRICT OF UTTAR PRADESH, INDIA

Purpose: A study of indoor radon and thoron has been carried out in the dwelling of Moradabad, Uttar Pradesh, India. Radon is an invisible radioactive gas that occurs naturally in the indoor atmosphere. It comes from the natural breakdown of uranium in soils and rocks. Lung cancer risk depends upon the concentration of radon, thoron and their decay product in the air. Methodology: The measurements of radon and thoron concentration were carried out by using LR-115 type II plastic track detectors (SSNTD Technique).  Findings: In the present study the value of radon concentration from10.5 Bq/m3to 30Bq/m3 with an average19.9Bq/m3and thoron concentration from 5.6 Bq/m3 to 24 Bq/m3 with an average of 14.9 Bq/m3. It is observed that radon and thoron concentration is maximum in winter and minimum during summer. The maximum concentration in winter is essentially influenced by the intense temperature inversion, which occurs in the winter season when the wind velocity is low. The maximum concentration in winter is also the result of decreased ventilation because in this season the houses are closed for a long time and radon/thoron accumulated inside the room and a weak positive correlation was observed between radon and thoron. Social Implications:  There are some difficulties in assessing the exact risks of radon in the home. Most studies have used data from miners who will have had far more exposure to radon than is likely in any building. Originality/ Novelty: This study is done at Moradabad City and Research Lab present in S.S.P. G. College Shajhanapur. Data of radon and thoron concentration has been taken from twin cup radon-thoron Dosimeter and Spark Counter

Star Clusters in Virgo and Fornax Dwarf Irregular Galaxies

We present the results of a search for clusters in dwarf irregular galaxies in the Virgo and Fornax Cluster using HST WFPC2 snapshot data. The galaxy sample includes 28 galaxies, 11 of which are confirmed members of the Virgo and Fornax clusters. In the 11 confirmed members, we detect 237 cluster candidates and determine their V magnitudes, V-I colors and core radii. After statistical subtraction of background galaxies and foreground stars, most of the cluster candidates have V-I colors of -0.2 and 1.4, V magnitudes lying between 20 and 25th magnitude and core radii between 0 and 6 pc. Using H-alpha observations, we find that 26% of the blue cluster candidates are most likely HII regions. The rest of the cluster candidates are most likely massive (>10^4 Msol) young and old clusters. A comparison between the red cluster candidates in our sample and the Milky Way globular clusters shows that they have similar luminosity distributions, but that the red cluster candidates typically have larger core radii. Assuming that the red cluster candidates are in fact globular clusters, we derive specific frequencies (S_N) ranging from ~0-9 for the galaxies. Although the values are uncertain, seven of the galaxies appear to have specific frequencies greater than 2. These values are more typical of ellipticals and nucleated dwarf ellipticals than they are of spirals or Local Group dwarf irregulars.Comment: 46 pages, 14 figures, 3 tables, accepted by AJ. Higher quality PS version of entire paper available at http://www.astro.washington.edu/seth/dirr_gcs.htm

Quantum Discord and Quantum Computing - An Appraisal

We discuss models of computing that are beyond classical. The primary motivation is to unearth the cause of nonclassical advantages in computation. Completeness results from computational complexity theory lead to the identification of very disparate problems, and offer a kaleidoscopic view into the realm of quantum enhancements in computation. Emphasis is placed on the `power of one qubit' model, and the boundary between quantum and classical correlations as delineated by quantum discord. A recent result by Eastin on the role of this boundary in the efficient classical simulation of quantum computation is discussed. Perceived drawbacks in the interpretation of quantum discord as a relevant certificate of quantum enhancements are addressed.Comment: To be published in the Special Issue of the International Journal of Quantum Information on "Quantum Correlations: entanglement and beyond." 11 pages, 4 figure

Socio economic profile of direct seeded rice (DSR) farmers of Haryana

The study has focused on socio economic profile, adoption level of Direct seeded rice (DSR) farmers and extension strategy to increase the adoption of DSR cultivation in Haryana (India). More than half of respondents (51.66 %) belonged to the middle age group 36-50 years and maximum 21.67 per-cent farmer qualification found metric. Majority of the farmers (50.83 per cent) had low level of socio-economic. Economic motivation of farmers was 70.83 per cent belonged to low to moderate level, whereas 67.5 per-cent of respondents belonged moderate to high innovation proneness. The overall adoption level of DSR technology was low to moderate, since 70 per-cent of respondents belonged to low to medium category