350 research outputs found
Cost comparison between PAV and ICE treatment with peripheral blood progenitor cells (PBPC) reinfusion in small-cell lung cancer (SCLC)
Cost comparison between PAV and ICE treatment with peripheral blood progenitor cells (PBPC) reinfusion in small-cell lung cancer (SCLC)
A Microscopic T-Violating Optical Potential: Implications for Neutron-Transmission Experiments
We derive a T-violating P-conserving optical potential for neutron-nucleus
scattering, starting from a uniquely determined two-body -exchange
interaction with the same symmetry. We then obtain limits on the T-violating
-nucleon coupling from neutron-transmission
experiments in Ho. The limits may soon compete with those from
measurements of atomic electric-dipole moments.Comment: 8 pages, 2 uuencoded figures in separate files (replaces version sent
earlier in the day with figures attached), in RevTeX 3, submitted to PR
Calculations of three-body observables in ^8B breakup
We discuss calculations of three-body observables for the breakup of ^8B on a
^{58}Ni target at low energy using the coupled discretised continuum channels
approach. Calculations of both the angular distribution of the ^7Be fragments
and their energy distributions are compared with those measured at several
laboratory angles. In these observables there is interference between the
breakup amplitudes from different spin-parity excitations of the projectile.
The resulting angle and the energy distributions reveal the importance of the
higher-order continuum state couplings for an understanding of the
measurements.Comment: 22 pages (postscript), accepted in Phys. Rev.
Clinical benefit of fulvestrant in postmenopausal women with advanced breast cancer and primary or acquired resistance to aromatase inhibitors: final results of phase II Swiss Group for Clinical Cancer Research Trial (SAKK 21/00)
Background: The aim of this study was to evaluate the efficacy and tolerability of fulvestrant, an estrogen receptor antagonist, in postmenopausal women with hormone-responsive tumors progressing after aromatase inhibitor (AI) treatment. Patients and methods: This is a phase II, open, multicenter, noncomparative study. Two patient groups were prospectively considered: group A (n = 70) with AI-responsive disease and group B (n = 20) with AI-resistant disease. Fulvestrant 250 mg was administered as intramuscular injection every 28 (±3) days. Results: All patients were pretreated with AI and 84% also with tamoxifen or toremifene; 67% had bone metastases and 45% liver metastases. Fulvestrant administration was well tolerated and yielded a clinical benefit (CB; defined as objective response or stable disease [SD] for ≥24 weeks) in 28% (90% confidence interval [CI] 19% to 39%) of patients in group A and 37% (90% CI 19% to 58%) of patients in group B. Median time to progression (TTP) was 3.6 (95% CI 3.0 to 4.8) months in group A and 3.4 (95% CI 2.5 to 6.7) months in group B. Conclusions: Overall, 30% of patients who had progressed following prior AI treatment gained CB with fulvestrant, thereby delaying indication to start chemotherapy. Prior response to an AI did not appear to be predictive for benefit with fulvestran
From the Bethe-Salpeter equation to non-relativistic approaches with effective two-body interactions
It is known that binding energies calculated from the Bethe-Salpeter equation
in ladder approximation can be reasonably well accounted for by an
energy-dependent interaction, at least for the lowest states. It is also known
that none of these approaches gives results close to what is obtained by using
the same interaction in the so-called instantaneous approximation, which is
often employed in non-relativistic calculations. However, a recently proposed
effective interaction was shown to account for the main features of both the
Bethe-Salpeter equation and the energy-dependent approach. In the present work,
a detailed comparison of these different methods for calculating binding
energies of a two-particle system is made. Some improvement, previously
incorporated for the zero-mass boson case in the derivation of the effective
interaction, is also employed for massive bosons. The constituent particles are
taken to be distinguishable and spinless. Different masses of the exchanged
boson (including a zero mass) as well as states with different angular momenta
are considered and the contribution of the crossed two-boson exchange diagram
is discussed. With this respect, the role played by the charge of the exchanged
boson is emphasized. It is shown that the main difference between the
Bethe-Salpeter results and the instantaneous approximation ones are not due to
relativity as often conjectured.Comment: 38 pages, 12 eps figures, uses elsart.cls (included
Survey of ground state neutron Spectroscopic Factors from Li to Cr isotopes
The ground state neutron spectroscopic factors for 80 nuclei ranging in Z
from 3 to 24 have been extracted by analyzing the past measurements of the
angular distributions from (d,p) and (p,d) reactions. We demonstrate an
approach that provides systematic and consistent values with minimum
assumptions. For the 61 nuclei that have been described by large-basis
shell-model calculations, most experimental spectroscopic factors are
reproduced to within 20%.Comment: 12 pages, 2 figures, 2 table
Shifting Business Models for a Circular Economy: Metals Management for Multi-Product-Use Cycles
The overarching aim of this report is to explore how the Australian metals and minerals sector could embrace new business models and build on its strengths to harness new value in a global economy orientated more towards sustainable future
Local and non-local equivalent potentials for p-12C scattering
A Newton-Sabatier fixed energy inversion scheme has been used to equate
inherently non-local p-C potentials at a variety of energies to pion
threshold, with exactly phase equivalent local ones. Those energy dependent
local potentials then have been recast in the form of non-local Frahn-Lemmer
interactions.Comment: 15 pages plus 9 figures submitted to Phys. Rev.
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