469 research outputs found

    A study of the achievement of pupils who studied the Harold Rugg's fused course in social studies as compared with those who studied separate history and geography courses

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    Not Available.Alice B. McGuirkNot ListedNot ListedMaster of ArtsDepartment Not ListedCunningham Memorial library, Terre Haute, Indiana State University.isua-thesis-1933-mcguirkMastersTitle from document title page. Document formatted into pages: contains 51p. : ill. Includes appendix and bibliography

    TLR2 and TLR4 in Ischemia Reperfusion Injury

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    Ischemia reperfusion (I/R) injury refers to the tissue damage which occurs when blood supply returns to tissue after a period of ischemia and is associated with trauma, stroke, myocardial infarction, and solid organ transplantation. Although the cause of this injury is multifactorial, increasing experimental evidence suggests an important role for the innate immune system in initiating the inflammatory cascade leading to detrimental/deleterious changes. The Toll-like Receptors (TLRs) play a central role in innate immunity recognising both pathogen- and damage-associated molecular patterns and have been implicated in a range of inflammatory and autoimmune diseases. In this paper, we summarise the current state of knowledge linking TLR2 and TLR4 to I/R injury, including recent studies which demonstrate that therapeutic inhibition of TLR2 has beneficial effects on I/R injury in a murine model of myocardial infarction

    Cooperative Carbon Dioxide Adsorption in Alcoholamine- and Alkoxyalkylamine-Functionalized Metal-Organic Frameworks.

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    A series of structurally diverse alcoholamine- and alkoxyalkylamine-functionalized variants of the metal-organic framework Mg2 (dobpdc) are shown to adsorb CO2 selectively via cooperative chain-forming mechanisms. Solid-state NMR spectra and optimized structures obtained from van der Waals-corrected density functional theory calculations indicate that the adsorption profiles can be attributed to the formation of carbamic acid or ammonium carbamate chains that are stabilized by hydrogen bonding interactions within the framework pores. These findings significantly expand the scope of chemical functionalities that can be utilized to design cooperative CO2 adsorbents, providing further means of optimizing these powerful materials for energy-efficient CO2 separations

    GP attitudes and self-reported behaviour in primary care consultations for low back pain

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    Background. The implementation of guideline recommendations in primary care has become widespread. The treatment of low back pain (LBP) has followed suite. Research shows that the use of LBP guidelines is influenced by the believability of the underlying evidence, the GPs consultation style and uncertainties surrounding diagnosis and treatment

    Soft branes in supersymmetry-breaking backgrounds

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    We revisit the analysis of effective field theories resulting from non-supersymmetric perturbations to supersymmetric flux compactifications of the type-IIB superstring with an eye towards those resulting from the backreaction of a small number of anti-D3-branes. Independently of the background, we show that the low-energy Lagrangian describing the fluctuations of a stack of probe D3-branes exhibits soft supersymmetry breaking, despite perturbations to marginal operators that were not fully considered in some previous treatments. We take this as an indication that the breaking of supersymmetry by anti-D3-branes or other sources may be spontaneous rather than explicit. In support of this, we consider the action of an anti-D3-brane probing an otherwise supersymmetric configuration and identify a candidate for the corresponding goldstino.Comment: 36+5 pages. References added, minor typos correcte

    Observation of modified radiative properties of cold atoms in vacuum near a dielectric surface

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    We have observed a distance-dependent absorption linewidth of cold 87^{87}Rb atoms close to a dielectric-vacuum interface. This is the first observation of modified radiative properties in vacuum near a dielectric surface. A cloud of cold atoms was created using a magneto-optical trap (MOT) and optical molasses cooling. Evanescent waves (EW) were used to observe the behavior of the atoms near the surface. We observed an increase of the absorption linewidth with up to 25% with respect to the free-space value. Approximately half the broadening can be explained by cavity-quantum electrodynamics (CQED) as an increase of the natural linewidth and inhomogeneous broadening. The remainder we attribute to local Stark shifts near the surface. By varying the characteristic EW length we have observed a distance dependence characteristic for CQED.Comment: 6 pages, 6 figures, some minor revision

    Noise limits in matter-wave interferometry using degenerate quantum gases

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    We analyze the phase resolution limit of a Mach-Zehnder atom interferometer whose input consists of degenerate quantum gases of either bosons or fermions. For degenerate gases, the number of atoms within one de Broglie wavelength is larger than unity, so that atom-atom interactions and quantum statistics are no longer negligible. We show that for equal atom numbers, the phase resolution achievable with fermions is noticeably better than for interacting bosons.Comment: 4 pages, 5 figure

    Uveal melanoma UK national guidelines

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    The United Kingdom (UK) uveal melanoma guideline development group used an evidence based systematic approach (Scottish Intercollegiate Guidelines Network (SIGN)) to make recommendations in key areas of uncertainty in the field including: the use and effectiveness of new technologies for prognostication, the appropriate pathway for the surveillance of patients following treatment for primary uveal melanoma, the use and effectiveness of new technologies in the treatment of hepatic recurrence and the use of systemic treatments. The guidelines were sent for international peer review and have been accredited by NICE. A summary of key recommendations is presented. The full documents are available on the Melanoma Focus website
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