6,887 research outputs found
Study of acoustic emission during mechanical tests of large flight weight tank structure
A polyphenylane oxide insulated, flight weight, subscale, aluminum tank was monitored for acoustic emissions during a proof test and during 100 cycles of environmental test simulating space flights. The use of a combination of frequency filtering and appropriate spatial filtering to reduce background noise was found to be sufficient to detect acoustic emission signals of relatively small intensity expected from subcritical crack growth in the structure. Several emission source locations were identified, including the one where a flaw was detected by post-test X-ray inspections. For most source locations, however, post-test inspections did not detect flaws; this was partially attributed to the higher sensitivity of the acoustic emission technique than any other currently available NDT method for detecting flaws
Assessment of cockpit interface concepts for data link retrofit
The problem is examined of retrofitting older generation aircraft with data link capability. The approach taken analyzes requirements for the cockpit interface, based on review of prior research and opinions obtained from subject matter experts. With this background, essential functions and constraints for a retrofit installation are defined. After an assessment of the technology available to meet the functions and constraints, candidate design concepts are developed. The most promising design concept is described in detail. Finally, needs for further research and development are identified
Evidence for the Gompertz Curve in the Income Distribution of Brazil 1978-2005
This work presents an empirical study of the evolution of the personal income
distribution in Brazil. Yearly samples available from 1978 to 2005 were studied
and evidence was found that the complementary cumulative distribution of
personal income for 99% of the economically less favorable population is well
represented by a Gompertz curve of the form , where
is the normalized individual income. The complementary cumulative
distribution of the remaining 1% richest part of the population is well
represented by a Pareto power law distribution . This
result means that similarly to other countries, Brazil's income distribution is
characterized by a well defined two class system. The parameters , ,
, were determined by a mixture of boundary conditions,
normalization and fitting methods for every year in the time span of this
study. Since the Gompertz curve is characteristic of growth models, its
presence here suggests that these patterns in income distribution could be a
consequence of the growth dynamics of the underlying economic system. In
addition, we found out that the percentage share of both the Gompertzian and
Paretian components relative to the total income shows an approximate cycling
pattern with periods of about 4 years and whose maximum and minimum peaks in
each component alternate at about every 2 years. This finding suggests that the
growth dynamics of Brazil's economic system might possibly follow a
Goodwin-type class model dynamics based on the application of the
Lotka-Volterra equation to economic growth and cycle.Comment: 22 pages, 15 figures, 4 tables. LaTeX. Accepted for publication in
"The European Physical Journal B
Trusted interoperability and the patient safety issues of parasitic health care software
With the proliferation of software systems and products in the healthcare environment, it is increasingly common for such software products to be constructed in a modular design. However, for modular software to be securely interoperable with other software products requires agreed consistent and accountable interfaces. This agreement may take the form of bilateral vendor to vendor arrangements or via a trusted external third-party who coordinates agreed interaction methods, such as a jurisdiction. Standards are a particular form of mutually trusted third party. Unfortunately, this agreed method of interoperability is not always present in vendor software. Where one software product or module interacts with another, in the absence of any agreement, it is referred to as ―bolt-on‖. It is perhaps more descriptive to refer to such software in terms of its potential to cause harm and refer to it using the biological analogy of ―parasitic‖ software and associated ―host‖ software. Analogous to biological systems, parasitic software can operate by data injection into or data extraction from, the associated host database. Both forms of parasitic software exploit access mechanisms or security flaws in the host software independent of the host vendor and in ways not intended or supported by the host vendor. This paper discusses the mechanics of this security vulnerability and more importantly, the potential adverse consequences to patient safety of such susceptibilities. As Australia moves to a national connected e-health system these issues are causes for grave concern. This paper provides a case study of this insecurity to highlight the problem, promote discussion and encourage potential change
A demonstration of motion base design alternatives for the National Advanced Driving Simulator
A demonstration of the capability of NASA's Vertical Motion Simulator to simulate two alternative motion base designs for the National Advanced Driving simulator (NADS) is reported. The VMS is located at ARC. The motion base conditions used in this demonstration were as follows: (1) a large translational motion base; and (2) a motion base design with limited translational capability. The latter had translational capability representative of a typical synergistic motion platform. These alternatives were selected to test the prediction that large amplitude translational motion would result in a lower incidence or severity of simulator induced sickness (SIS) than would a limited translational motion base. A total of 10 drivers performed two tasks, slaloms and quick-stops, using each of the motion bases. Physiological, objective, and subjective measures were collected. No reliable differences in SIS between the motion base conditions was found in this demonstration. However, in light of the cost considerations and engineering challenges associated with implementing a large translation motion base, performance of a formal study is recommended
Casimir micro-sphere diclusters and three-body effects in fluids
Our previous article [Phys. Rev. Lett. 104, 060401 (2010)] predicted that
Casimir forces induced by the material-dispersion properties of certain
dielectrics can give rise to stable configurations of objects. This phenomenon
was illustrated via a dicluster configuration of non-touching objects
consisting of two spheres immersed in a fluid and suspended against gravity
above a plate. Here, we examine these predictions from the perspective of a
practical experiment and consider the influence of non-additive, three-body,
and nonzero-temperature effects on the stability of the two spheres. We
conclude that the presence of Brownian motion reduces the set of experimentally
realizable silicon/teflon spherical diclusters to those consisting of layered
micro-spheres, such as the hollow- core (spherical shells) considered here.Comment: 11 pages, 9 figure
Variable Step Random Walks and Self-Similar Distributions
We study a scenario under which variable step random walks give anomalous
statistics. We begin by analyzing the Martingale Central Limit Theorem to find
a sufficient condition for the limit distribution to be non-Gaussian. We note
that the theorem implies that the scaling index is 1/2. For
corresponding continuous time processes, it is shown that the probability
density function satisfies the Fokker-Planck equation. Possible forms
for the diffusion coefficient are given, and related to . Finally, we
show how a time-series can be used to distinguish between these variable
diffusion processes and L\'evy dynamics.Comment: 13pages, 2 figure
Charge Transport in the Dense Two-Dimensional Coulomb Gas
The dynamics of a globally neutral system of diffusing Coulomb charges in two
dimensions, driven by an applied electric field, is studied in a wide
temperature range around the Berezinskii-Kosterlitz-Thouless transition. I
argue that the commonly accepted ``free particle drift'' mechanism of charge
transport in this system is limited to relatively low particle densities. For
higher densities, I propose a modified picture involving collective ``partner
transfer'' between bound pairs. The new picture provides a natural explanation
for recent experimental and numerical findings which deviate from standard
theory. It also clarifies the origin of dynamical scaling in this context.Comment: 4 pages, RevTeX, 2 eps figures included; some typos corrected, final
version to be published in Phys. Rev. Let
Proteasomal Interference Prevents Zona Pellucida Penetration and Fertilization in Mammals
doi: 10.1095/biolreprod.104.032532The ubiquitin-proteasome pathway has been implicated in the penetration of ascidian vitelline envelope by the fertilizing
spermatozoon (Sawada et al., Proc Natl Acad Sci U S A 2002; 99:1223-1228). The present study provides experimental evidence
demonstrating proteasome involvement in the penetration of mammalian zona pellucida (ZP). Using porcine in vitro fertilization as a model, penetration of ZP was completely inhibited by specific proteasomal inhibitors MG-132 and lactacystin. Three commercial rabbit sera recognizing 20S proteasomal
core subunits b-1i, b-2i, a-6, and b-5 completely blocked fertilization at a very low concentration (i.e., diluted 1/2000 to 1/8000 in fertilization medium). Neither proteasome inhibitors nor antibodies had any effects on sperm-ZP binding and acrosome exocytosis in zona-enclosed oocytes or on fertilization
rates in zona-free oocytes, which were highly polyspermic. Consistent with a possible role of ubiquitin-proteasome pathway in ZP penetration, ubiquitin and various a and b type proteasomal subunits were detected in boar sperm acrosome by specific antibodies,
immunoprecipitated and microsequenced by MALDITOF from boar sperm extracts. Antiubiquitin-immunoreactive substrates were detected on the outer face of ZP by epifluorescence microscopy. This study therefore provides strong evidence implicating the ubiquitin-proteasome pathway in mammalian
fertilization and zona penetration. This finding opens a new line of acrosome/ZP research because further studies of the sperm
acrosomal proteasome can provide new tools for the management of polyspermia during in vitro fertilization and identify new targets for contraceptive development
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