State of the autonomic nervous system in men with idiopathic manifestations of overactive bladder

As a result of routine inspections of an organized group of healthy men 35–55 years, 1.5 % revealed abnormalities in the urinary tract are not contacts to urological disorders. As a result of a comprehensive survey neurological they are classified as idiopathic overactive bladder. A study of the parameters of the autonomic nervous system as one of the regulators of the process of urination and a possible trigger revealed pathology. The analysis of the comparative study of kardiointervalogramm and spectral analysis of heart rate revealed that the clinical manifestations of idiopathic overactive bladder in men realized in terms of tension of regulatory systems dominated by executives sympathoadrenal autonomic nervous system.</em

Materials for spintronics: electronic and transport properties of the zigzag graphene nanoribbon/hexagonal boron nitride heterostructures

Abstract High charge carrier mobility in graphene at room temperature creates large potentials for the fabrication of electronic and spintronic devices For creating HEMT (high electron mobility transistor) devices based on ZGNR it is extremely important to study charge carriers mobility. It is necessary to understand and to be able to control the transport properties of electronic devices. Thus, in this work, the effects of the edge and substrate on the band gap, magnetism and transport properties of the charge carriers in 8-ZGNR/h-BN Band structure calculations were performed using the Quantum Espresso For both carrier types in the N-ZGNR/h-BN(0001) heterostructures a common picture is observed: increasing carrier mobility with the decrease of the number of dimers in nanoribbon. For electrons, the mobility increases from . It should also be noted that according to the PBEsol (PBE-D2) calculations the values of the carrier mobility in N-ZGNR/h-BN(0001) heterostructures appear to be 3.5% (7%) higher than in ZGNR without substrate. Thus, the influence of substrate and nanoribbon width on the low-energy spectrum of $\pi$-electrons, local magnetic moments of interface atoms, and the mobilities of charge carriers in N-ZGNR/h-BN(0001) (N = 2, 4, 6, 8) heterostructures have been studied using ab-initio plane-wave pseudopotential method within the DFT framework. Using two different approximations for total energy functional (PBEsol, PBE-D2) we have ascertained the effect of increase of charge carriers mobility by reduction of dimers&apos; number in nanoribbons. Our DFT study have shown that the mobilities of charge carriers in N-ZGNR/h-BN(0001) heterostructures were 5% higher than in suspended nanoribbons. Predicted high electro

Shapiro Effect as a Possible Cause of the Low-Frequency Pulsar Timing Noise in Globular Clusters

A prolonged timing of millisecond pulsars has revealed low-frequency uncorrelated noise, presumably of astrophysical origin, in the pulse arrival time (PAT) residuals for some of them. In most cases, pulsars in globular clusters show a low-frequency modulation of their rotational phase and spin rate. The relativistic time delay of the pulsar signal in the curved space time of randomly distributed and moving globular cluster stars (the Shapiro effect) is suggested as a possible cause of this modulation. Given the smallness of the aberration corrections that arise from the nonstationarity of the gravitational field of the randomly distributed ensemble of stars under consideration, a formula is derived for the Shapiro effect for a pulsar in a globular cluster. The derived formula is used to calculate the autocorrelation function of the low-frequency pulsar noise, the slope of its power spectrum, and the behavior of the $\sigma_z$ statistic that characterizes the spectral properties of this noise in the form of a time function. The Shapiro effect under discussion is shown to manifest itself for large impact parameters as a low-frequency noise of the pulsar spin rate with a spectral index of n=-1.8 that depends weakly on the specific model distribution of stars in the globular cluster. For small impact parameters, the spectral index of the noise is n=-1.5.Comment: 23 pages, 6 figure

The treatment necrotising enterocolitis in newborns

In modern neonatal surgery, the treatment of necrotizing enterocolitis (NEC) in infants remains the subject of lively discussion. The results of treatment of 24 newborns with NEC, who were in the Aktobe medical center in the period 2015-2017. A positive result was obtained in 2 children after conservative therapy. In 22 cases, children entered the III-IV stages of NEC. 15 children underwent laparocentesis and drainage of the abdominal cavity at the stage of preoperative preparation. In 7 cases laparocentesis was not performed. 21 children with NEC underwent surgical treatment in different periods of inpatient treatment. Laparoscopy was performed in 1 child, laparotomy in 20 children. Mortality rate was 41.6%. Postoperative lethality 42,8%. High mortality was observed in a group of premature babies with concomitant pathology of other organs. The number of patients with NEC with a very low body weight has increased. Mandatory laparocentesis with drainage of the abdominal cavity in the preoperative period positively affects the results of treatment. The early initiation of treatment by neonatologists in the pediatric stage of NEC leads to a disruption in the staging of the disease, to a distortion of the pattern of intra-abdominal catastrophe, especially when infiltrative-adhesive forms of necrotic enterocolitis with a subacute course of the disease. Deferred surgical treatment leads to the spread of the process and an unfavorable outcome. Necrotic changes in the primary parts of the jejunum compel the surgeon to form high stoms. The formation of magneto-compression anastomoses in the postoperative period would help in solving the problem of early closure with anjejunostoms. The analysis of the results of treatment corresponds to the results of a large number of scientific works and shows the changes that have occurred in recent years in the clinic and the diagnosis of necrotizing enterocolitis.В современной хирургии новорожденных лечение некротизирующего энтероколита (НЭК) у младенцев остается предметом оживленной дискуссии. Приведены результаты лечения 24 новорожденных детей с НЭК, находившихся в Актюбинском медицинском центре в период 2015—2017 гг. У 2-х детей после проведения консервативной терапии получен положительный результат. В 22 случаях дети поступили на III—IV стадиях НЭК. У 15 детей проводился лапароцентез и дренирование брюшной полости на этапе предоперационной подготовки. В 7 случаях лапароцентез не выполнялся. 21 детей с НЭК подверглись оперативному лечению в различные сроки стационарного лечения. Лапароскопия проводилась у 1 ребенка, лапаротомия — у 20 детей. Летальность составила 41,6%. Послеоперационная летальность — 42,8%. Высокая летальность наблюдалась в группе недоношенных детей с сопутствующей патологией других органов. Возросло число пациентов с НЭК с очень низкой и экстремально низкой массой тела. Обязательное проведение лапароцентеза с дренированием брюшной полости в предоперационном периоде положительно отражается на результатах лечения. Раннее начало лечения неонатологами в педиатрической стадии НЭК приводит к нарушению стадийности заболевания, к искажению картины внутрибрюшной катастрофы, особенно при инфильтративно-спаечных формах некротического энтероколита с подострым течением заболевания. Отложенное оперативное лечение приводит к распространению процесса и неблагоприятному исходу. Некротические изменения в начальных отделах тощей кишки вынуждают хирурга формировать высокие еюностомы. Формирование магнитно-компрессионных анастомозов в послеоперационном периоде способствует решению проблемы раннего закрытия еюностом. Проведенный анализ результатов лечения соответствует результатам большого количества научных работ, где показаны изменения, произошедшие в последние годы в клинике и диагностике некротизирующего энтероколита

Simultaneous measurements of water optical properties by AC9 transmissometer and ASP-15 Inherent Optical Properties meter in Lake Baikal

Measurements of optical properties in media enclosing Cherenkov neutrino telescopes are important not only at the moment of the selection of an adequate site, but also for the continuous characterization of the medium as a function of time. Over the two last decades, the Baikal collaboration has been measuring the optical properties of the deep water in Lake Baikal (Siberia) where, since April 1998, the neutrino telescope NT-200 is in operation. Measurements have been made with custom devices. The NEMO Collaboration, aiming at the construction of a km3 Cherenkov neutrino detector in the Mediterranean Sea, has developed an experimental setup for the measurement of oceanographic and optical properties of deep sea water. This setup is based on a commercial transmissometer. During a joint campaign of the two collaborations in March and April 2001, light absorption, scattering and attenuation in water have been measured. The results are compatible with previous ones reported by the Baikal Collaboration and show convincing agreement between the two experimental techniques.Comment: 16 pages, submitted to NIM-

Comparative characteristics of immunity in patients with urological diseases

The study involved 335 patients with urological clinic. All patients with the clinical forms of the disease were divided into two groups. The first group of patients with stone disease without evidence of pyelonephritis, a second group of patients with urolithiasis, chronic pyelonephritis. Found that patients with stone disease, uncomplicated by inflammation of the kidneys, significant changes in the immune system occurs. Urolithiasis complicated pyelonephritis, significantly increases levels of proinflammatory and anti-inflammatory mediators of the immune response is activated by the metabolic activity of neutrophils while reducing their phagocytic and absorptive function, and the weakening of the bactericidal activity of serum.Обследовано 335 больных урологического стационара. Все пациенты с учетом клинических форм заболевания были разделены на две группы. Первая группа больные с мочекаменной болезнью без признаков пиелонефрита, вторая группа больных с мочекаменной болезнью и хроническим пиелонефритом. Установлено, что у больных мочекаменной болезнью, не осложненной воспалительным процессом в почках, значительных сдвигов в иммунной системе не происходит. При мочекаменной болезни, осложненной пиелонефритом, значительно возрастает уровень провоспалительных и противовоспалительных медиаторов иммунного ответа, активируется метаболической активностью нейтрофилов одновременно со снижением их фагоцитарной и поглотительной функцией, а также ослаблением бактерицидной активности сыворотки крови

Constraints on dark matter-nucleon effective couplings in the presence of kinematically distinct halo substructures using the DEAP-3600 detector

DEAP-3600 is a single-phase liquid argon detector aiming to directly detect Weakly Interacting Massive Particles (WIMPs), located at SNOLAB (Sudbury, Canada). After analyzing data taken during the first year of operation, a null result was used to place an upper bound on the WIMP-nucleon spin-independent, isoscalar cross section. This study reinterprets this result within a Non-Relativistic Effective Field Theory framework, and further examines how various possible substructures in the local dark matter halo may affect these constraints. Such substructures are hinted at by kinematic structures in the local stellar distribution observed by the Gaia satellite and other recent astronomical surveys. These include the Gaia Sausage (or Enceladus), as well as a number of distinct streams identified in recent studies. Limits are presented for the coupling strength of the effective contact interaction operators $\mathcal{O}_1$, $\mathcal{O}_3$, $\mathcal{O}_5$, $\mathcal{O}_8$, and $\mathcal{O}_{11}$, considering isoscalar, isovector, and xenonphobic scenarios, as well as the specific operators corresponding to millicharge, magnetic dipole, electric dipole, and anapole interactions. The effects of halo substructures on each of these operators are explored as well, showing that the $\mathcal{O}_5$ and $\mathcal{O}_8$ operators are particularly sensitive to the velocity distribution, even at dark matter masses above 100 GeV/$c^2$

The liquid-argon scintillation pulseshape in DEAP-3600

DEAP-3600 is a liquid-argon scintillation detector looking for dark matter. Scintillation events in the liquid argon (LAr) are registered by 255 photomultiplier tubes (PMTs), and pulseshape discrimination (PSD) is used to suppress electromagnetic background events. The excellent PSD performance of LAr makes it a viable target for dark matter searches, and the LAr scintillation pulseshape discussed here is the basis of PSD. The observed pulseshape is a combination of LAr scintillation physics with detector effects. We present a model for the pulseshape of electromagnetic background events in the energy region of interest for dark matter searches. The model is composed of (a) LAr scintillation physics, including the so-called intermediate component, (b) the time response of the TPB wavelength shifter, including delayed TPB emission at O(ms) time-scales, and c) PMT response. TPB is the wavelength shifter of choice in most LAr detectors. We find that approximately 10% of the intensity of the wavelength-shifted light is in a long-lived state of TPB. This causes light from an event to spill into subsequent events to an extent not usually accounted for in the design and data analysis of LAr-based detectors