BK virus-induced nephritis and cystitis after matched unrelated donor stem cell transplantation: A case report

Currently, there is no standard therapy for a BK virus infection of the urogenital tract in immunocompromised, stem cell transplanted patients, so that early diagnosis and introduction of supportive measures have the highest response rates to date. © 2020 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd

N-(2,5-Dichloro­phen­yl)-4-methyl­benzene­sulfonamide

In the title compound, C13H11Cl2NO2S, the N—C bond in the C—SO2—NH—C segment has gauche torsion angles with respect to the S=O bonds. The mol­ecule is bent at the S atom with an C—SO2—NH—C torsion angle of 62.1 (2)°. Furthermore, the conformation of the N—H bond is syn to the ortho-chloro group in the adjacent benzene ring. The benzene rings are tilted by 67.8 (1)° relative to each other. The crystal structure features dimers linked by N—H⋯O hydrogen bonds. An intra­molecular N—H⋯Cl hydrogen bond is also observed

4-Chloro-N-(2,3-dichloro­phen­yl)benzene­sulfonamide

In the title compound, C12H8Cl3NO2S, the two aromatic rings are tilted relative to each other by 56.5 (1)°. The crystal structure features centrosymmetric dimers in which mol­ecules are linked by N—H⋯O hydrogen bonds

4-Sulfamoylanilinium nitrate

In the crystal structure of the title compound, C6H9N2O2S+·NO3 −, the cations and anions are connected by N—H⋯O hydrogen bonds into a three-dimensional network

Cold Atmospheric Plasma in the Treatment of Osteosarcoma

Human osteosarcoma (OS) is the most common primary malignant bone tumor occurring most commonly in adolescents and young adults. Major improvements in disease-free survival have been achieved by implementing a combination therapy consisting of radical surgical resection of the tumor and systemic multi-agent chemotherapy. However, long-term survival remains poor, so novel targeted therapies to improve outcomes for patients with osteosarcoma remains an area of active research. This includes immunotherapy, photodynamic therapy, or treatment with nanoparticles. Cold atmospheric plasma (CAP), a highly reactive (partially) ionized physical state, has been shown to inherit a significant anticancer capacity, leading to a new field in medicine called “plasma oncology.” The current article summarizes the potential of CAP in the treatment of human OS and reviews the underlying molecular mode of action

2,4-Dimethyl-N-(4-methyl­phen­yl)benzene­sulfonamide

The asymmetric unit of the crystal of the title compound, C15H17NO2S, contains two independent mol­ecules, which are twisted at the S—N bonds with C—SO2—NH—C torsion angles of 48.3 (2) (mol­ecule 1) and −75.7 (3)° (mol­ecule 2). The dihedral angles between the benzene rings are 72.0 (1) (mol­ecule 1) and 78.3 (1)° (mol­ecule 2). The crystal structure features inversion dimers linked by pairs of N—H⋯O hydrogen bonds

4-Chloro-N-(3,4-dimethyl­phen­yl)benzene­sulfonamide

In the title compound, C14H14ClNO2S, the angle between the sulfonyl and aniline benzene rings is 65.5 (1)°. The crystal structure features inversion dimers linked by pairs of N—H⋯O hydrogen bonds. The dimethyl­phenyl ring is disordered over two different orientations approximately related by a 180° rotation about the C—N bond, with occupancies of 0.643 (6) and 0.357 (6)

N-(2,6-Dichloro­phen­yl)benzene­sulfonamide

In the title compound, C12H9Cl2NO2S, the mol­ecule is bent at the S atom with a C—SO2—NH—C torsion angle of 82.5 (2)°. The benzene rings are tilted relative to each other by 43.5 (1)°. The crystal structure features chains linked by N—H⋯O hydrogen bonds

2,4-Dichloro-N-(3-chloro­phen­yl)benzene­sulfonamide

In the title compound, C12H8Cl3NO2S, the conformation of the N—H bond in the C—SO2—NH—C segment is anti to the meta-Cl in the aniline ring. The mol­ecule is twisted at the S atom, the C—SO2—NH—C torsion angle being 62.3 (2)°. The dihedral angle between the two benzene rings is 69.3 (1)°. The crystal structure features inversion dimers linked by pairs of N—H⋯O hydrogen bonds