9,448 research outputs found
Labor Market Shocks and Retirement: Do Government Programs Matter?
This paper examines how unemployment affects retirement and whether the Unemployment Insurance (UI) system and Social Security (SS) system affect how older workers respond to labor market shocks. To do so, we use pooled cross-sectional data from the March Current Population Survey (CPS) as well as March CPS files matched between one year and the next and longitudinal data from the Health and Retirement Survey (HRS). We find that downturns in the labor market increase retirement transitions. The magnitude of this effect is comparable to that associated with moderate changes in financial incentives to retire and to the threat of a health shock to which older workers are exposed. Interestingly, retirements only increase in response to an economic downturn once workers become SS-eligible, suggesting that retirement benefits may help alleviate the income loss associated with a weak labor market. We also estimate the impact of UI generosity on retirement and find little consistent evidence of an effect. This suggests that in some ways SS may serve as a more effective form of unemployment insurance for older workers than UI.
Radiation heating in selected NERVA engine components
The role of heating from nuclear radiation in design of the NERVA engine is treated. Some components are subjected to very high gamma heating rates in excess of 0.5 Btu/cubic inch/sec in steel in the primary nozzle or 0.25 Btu/cubic inch/sec in aluminum in the pressure vessel. These components must be cooled by a fraction of the liquid hydrogen propellant before it is passed through the core, heated, and expanded out the nozzle as a gas. Other components that are subjected to lower heating rates such as the thrust structure and the disk shield are designed so that they would not require liquid hydrogen cooling. Typical gamma and neutron heating rates, resulting temperatures, and their design consequences are discussed. Calculational techniques used in the nuclear and thermal analyses of the NERVA engine are briefly treated
Costs and Benefits of Full Dual-Frame Telephone Survey Designs
Assesses the cost, sample composition, weighting, and substantive effect on survey results involved in interviewing respondents by cell phone, including those with landlines. Includes demographic profiles of cell phone-only, landline-only, and dual users
GM1 Ganglioside Modifies α-Synuclein Toxicity and is Neuroprotective in a Rat α-Synuclein Model of Parkinson\u27s Disease.
While GM1 may interact with α-synuclein in vitro to inhibit aggregation, the ability of GM1 to protect against α-synuclein toxicity in vivo has not been investigated. We used targeted adeno-associated viral vector (AAV) overexpression of human mutant α-synuclein (A53T) in the rat substantia nigra (SN) to produce degeneration of SN dopamine neurons, loss of striatal dopamine levels, and behavioral impairment. Some animals received daily GM1 ganglioside administration for 6 weeks, beginning 24 hours after AAV-A53T administration or delayed start GM1 administration for 5 weeks beginning 3 weeks after AAV-A53T administration. Both types of GM1 administration protected against loss of SN dopamine neurons and striatal dopamine levels, reduced α-synuclein aggregation, and delayed start administration of GM1 reversed early appearing behavioral deficits. These results extend prior positive results in MPTP models, are consistent with the results of a small clinical study of GM1 in PD patients that showed slowing of symptom progression with chronic use, and argue for the continued refinement and development of GM1 as a potential disease modifying therapy for PD
Edaq530: a transparent, open-end and open-source measurement solution in natural science education
We present Edaq530, a low-cost, compact and easy-to-use digital measurement
solution consisting of a thumb-sized USB-to-sensor interface and a measurement
software. The solution is fully open-source, our aim being to provide a viable
alternative to professional solutions. Our main focus in designing Edaq530 has
been versatility and transparency. In this paper, we shall introduce the
capabilities of Edaq530, complement it by showing a few sample experiments, and
discuss the feedback we have received in the course of a teacher training
workshop in which the participants received personal copies of Edaq530 and
later made reports on how they could utilise Edaq530 in their teaching
Interactive manipulation of microparticles in an octagonal sonotweezer
An ultrasonic device for micro-patterning and precision manipulation of micrometre-scale particles is demonstrated. The device is formed using eight piezoelectric transducers shaped into an octagonal cavity. By exciting combinations of transducers simultaneously, with a controlled phase delay between them, different acoustic landscapes can be created, patterning micro-particles into lines, squares, and more complex shapes. When operated with all eight transducers the device can, with appropriate phase control, manipulate the two dimensional acoustic pressure gradient; it thus has the ability to position and translate a single tweezing zone to different locations on a surface in a precise and programmable manner
Recommended from our members
Fortification and health: challenges and opportunities.
Fortification is the process of adding nutrients or non-nutrient bioactive components to edible products (e.g., food, food constituents, or supplements). Fortification can be used to correct or prevent widespread nutrient intake shortfalls and associated deficiencies, to balance the total nutrient profile of a diet, to restore nutrients lost in processing, or to appeal to consumers looking to supplement their diet. Food fortification could be considered as a public health strategy to enhance nutrient intakes of a population. Over the past century, fortification has been effective at reducing the risk of nutrient deficiency diseases such as beriberi, goiter, pellagra, and rickets. However, the world today is very different from when fortification emerged in the 1920s. Although early fortification programs were designed to eliminate deficiency diseases, current fortification programs are based on low dietary intakes rather than a diagnosable condition. Moving forward, we must be diligent in our approach to achieving effective and responsible fortification practices and policies, including responsible marketing of fortified products. Fortification must be applied prudently, its effects monitored diligently, and the public informed effectively about its benefits through consumer education efforts. Clear lines of authority for establishing fortification guidelines should be developed and should take into account changing population demographics, changes in the food supply, and advances in technology. This article is a summary of a symposium presented at the ASN Scientific Sessions and Annual Meeting at Experimental Biology 2014 on current issues involving fortification focusing primarily on the United States and Canada and recommendations for the development of responsible fortification practices to ensure their safety and effectiveness
- …
