The relationships of phenotype, genotype and some environmental factors with birth weight in Jersey calves

This study investigated the effects of parity, birth type, gender and birth season on birth weight in Jersey cattle and also investigated the relationships of phenotype and genotype with birth weight. Birth records of the Karakoy farm near Samsun, Turkey for the period from 1998 to 2005 were used as data for this study. Parity (P < 0.001), birth type (P < 0.001) and gender (P < 0.001) had a significant effect on birth weight, whereas season of calving and calving year (P > 0.05) were not significant. The birth weight mean of Jersey calves was 20.87 ± 1.79 kg. Total additive genotypic variance was 14.80, phenotypic variance was 38.95 and heritability of birth weight was 0.38. In planning a selection program to achieve ideal birth weight of Jersey calves, birth type, gender and parity need to be included, with the 4th or later parity been most influential.Key words: Birth weight, estimate of parameter, Jersey, parity, season of birth

Migration of a Rigid Mitral Valve Ring

PubMed ID: 19049784[No abstract available

Mid-term results of peripheric cannulation after port-access surgery

PubMed ID: 17846077Several minimally invasive approaches, avoiding median sternotomy, have been described within the last few years for cardiac surgery. Femoral arterial and venous cannulation for extracorporeal perfusion are required for many of these operations. The aim of this report is to assess the long-term outcomes of femoral cannulations in patients who underwent minimally invasive procedures. One hundred and sixty patients underwent operations by the port-access method between January 2002 and October 2006. Cardiopulmonary bypass was established by femoral artery-vein cannulation, and a transthoracic clamp was used for the aortic occlusion. One hundred and twenty-one patients were under follow-up in the outpatient clinic and 85 patients underwent Doppler ultrasonography (US) for femoral arterial and venous stenosis. The mean follow-up was 27.9 months (range 1-57 months). There were three hospital mortalities (1.86%), and five late mortalities in this series. The mean follow-up for the Doppler examination was 20.54 months (range 1-56 months). There were two seromas and three wound complications (2.48%), all of which healed after outpatient treatment. All of the flow patterns of the common femoral arteries (CFA) were triphasic except in three of the patients. Three patients (2.48%) were found to have arterial stenosis. One patient with intermittant claudication underwent percutaneous dilatation and stenting of the CFA. Doppler US detected luminal narrowing in two patients who had been having no symptoms, and they are being followed in the outpatient clinic without any complaints. We found a chronic recanalized thrombotic change in the common femoral vein (CFV) in one patient (0.63%). Our study demonstrates vessel patency and/or stenosis in patients without complaints. In conclusion, femoral artery and vein cannulation for port-access surgery with transthoracic clamping can be performed successfully with excellent results in the mid-term. © 2007 Published by European Association for Cardio-Thoracic Surgery. All rights reserved

SURGICAL PLACEMENT OF LEFT VENTRICULAR LEAD FOR CARDIAC RESYNCHRONIZATION THERAPY AFTER FAILURE OF PERCUTANEOUS ATTEMPTS

WOS: 000317946500175

EPICARDIAL ADIPOSE TISSUE FATTY ACID BINDING PROTEIN 4 EXPRESSION IS CORRELATED WITH EXTENSION OF CORONARY ATHEROSCLEROSIS IN PATIENTS WITH METABOLIC SYNDROME

78th Congress of the European-Atherosclerosis-Society -- JUN 20-23, 2010 -- Hamburg, GERMANYWOS: 000278998800485…European Atherosclerosis So

Relationships between visceral/subcutaneous adipose tissue FABP4 expression and coronary atherosclerosis in patients with metabolic syndrome

Gormez, Selcuk/0000-0002-3546-3369WOS: 000520851300009PubMed: 31927390Background: Cytoplasmic fatty acid-binding proteins facilitate the transport of lipids to specific compartments in cells. Fatty acid-binding protein 4 (FABP4), also known as aP2 or A-FABP, plays a key role in the development of atherosclerosis, insulin resistance, obesity, and metabolic syndrome (MS). the FABP4 polymorphisms are associated with protein expression changes in vitro and metabolic and vascular alterations in vivo. the aim of this study was to investigate the association between FABP4 messenger ribonucleic acid (mRNA) expression levels in epicardial (EAT), pericardial (PAT), and subcutaneous adipose tissues (SAT), and the extent of coronary atherosclerosis in coronary artery disease (CAD) patients with MS. Furthermore, the relationship between the extent of coronary atherosclerosis and epicardial adipose tissue volume (EATV) and FABP4 gene variations was evaluated. Patients and methods: A total of 37 patients undergoing coronary artery bypass grafting because of CAD (MS CAD group) and 23 non-MS patients undergoing heart valve surgery (control group) were included. Coronary angiography was performed for all patients and the extent of coronary atherosclerosis was assessed using the Sullivan's scoring system. the mRNA expression levels of FABP4 gene in EAT, PAT, and SAT, and FABP4 polymorphisms were analyzed using the quantitative real-time polymerase chain reaction (qRT-PCR). Results: An increased FABP4 expression was observed in EAT and PAT of MS CAD group compared to controls. in the MS CAD group, FABP4 mRNA expression levels in EAT was 2.8-fold higher compared to PAT. the expression of FABP4 in EAT was positively correlated with the extent of atherosclerosis and EATV in MS CAD group (r = 0.588, P = 0.001, r = 0.174, P = 0.001, respectively). There were no correlations between PAT and SAT versus the extent of atherosclerosis and EATV. the FABP4 EAT mRNA expression levels were found to significantly increase in mutant allele carriers of rs1054135, whereas they significantly decreased in mutant allele carriers of rs77878271 (T-87C) in MS CAD group (P < 0.05). the extent of atherosclerosis was also found to be significantly associated with rs1054135 (P < 0.05). A cut-off point of 57.5 cm(3) EATV was used indicating the presence of CAD with a significant area under the curve of 0.783%, 98% sensitivity, and 100% specificity (95% CI 0.620-0.880; P < 0.05). Conclusions: Our study results suggest that FABP4 expression in EAT is strongly associated with the extent of atherosclerosis and EATV in MS CAD patients. (C) 2019 Published by Elsevier Inc.Turkish Diabetes FoundationThe authors would like to thank to the late Prof. Ahmet Sevim Buyukdevrim for his valuable support and advice to the manuscript. This work was supported by Turkish Diabetes Foundation