Multiple myeloma

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What do implicit measures measure?

We identify several ongoing debates related to implicit measures, surveying prominent views and considerations in each debate. First, we summarize the debate regarding whether performance on implicit measures is explained by conscious or unconscious representations. Second, we discuss the cognitive structure of the operative constructs: are they associatively or propositionally structured? Third, we review debates whether performance on implicit measures reflects traits or states. Fourth, we discuss the question of whether a person’s performance on an implicit measure reflects characteristics of the person who is taking the test or characteristics of the situation in which the person is taking the test. Finally, we survey the debate about the relationship between implicit measures and (other kinds of) behavior

Big brother is watching - using digital disease surveillance tools for near real-time forecasting

Abstract for the International Journal of Infectious Diseases 79 (S1) (2019).https://www.ijidonline.com/article/S1201-9712(18)34659-9/abstractPublished versio

Big Data Opportunities for Global Infectious Disease Surveillance

Simon Hay and colleagues discuss the potential and challenges of producing continually updated infectious disease risk maps using diverse and large volume data sources such as social media

A Minimal Length from the Cutoff Modes in Asymptotically Safe Quantum Gravity

Within asymptotically safe Quantum Einstein Gravity (QEG), the quantum 4-sphere is discussed as a specific example of a fractal spacetime manifold. The relation between the infrared cutoff built into the effective average action and the corresponding coarse graining scale is investigated. Analyzing the properties of the pertinent cutoff modes, the possibility that QEG generates a minimal length scale dynamically is explored. While there exists no minimal proper length, the QEG sphere appears to be "fuzzy" in the sense that there is a minimal angular separation below which two points cannot be resolved by the cutoff modes.Comment: 26 pages, 1 figur

Staphylococcus aureus Nasal Carriage among Beefpacking Workers in a Midwestern United States Slaughterhouse

Occupational contact with livestock is an established risk factor for exposure to livestock-associated methicillin-resistant Staphylococcus aureus (MRSA), particularly among industrial swine workers. While S. aureus is known to infect cattle, livestock-associated S. aureuscarriage among workers in the beef production chain has received limited attention. Beefpacking workers, who slaughter, butcher and process cattle, have intensified exposure to potentially infectious animal materials and may be at risk of livestock-associated S. aureusexposure. We conducted a cross-sectional study of beefpacking workers (n = 137) at an industrial slaughterhouse in the Midwestern United States to evaluate prevalence and characteristics of S. aureus nasal colonization, specifically the absence of the scn gene to identify putative association with livestock, antibiotic susceptibility, presence of Panton-Valentin leukocidin (PVL) genes lukS-PV and lukF-PV, and spa type. Overall prevalence of S.aureus nasal carriage was 27.0%. No workers carried livestock-associated MRSA. Methicillin-sensitive S. aureus isolates (MSSA) recovered from five workers (3.6%) lacked the scn gene and were considered putative livestock-associated S. aureus (pLA-SA). Among pLA-SA isolates, spa types t338, t748, t1476 and t2379 were identified. To our knowledge, these spatypes have not previously been identified as associated with livestock. Prevalence of human-adapted MRSA carriage in workers was 3.6%. MRSA isolates were identified as spa types t002, t008 and t024, and four of five MRSA isolates were PVL-positive. To date, this is the first study to indicate that industrial beefpacking workers in the United States may be exposed to livestock-associated S. aureus, notably MSSA, and to spa types not previously identified in livestock and livestock workers. Occupational exposure to livestock-associated S. aureus in the beef production chain requires further epidemiologic investigation

The Relationship Between Landing Mechanics and Injury Risk in Women\u27s Collegiate Soccer Players

Mechanical performance in landing related tasks has been suggested to be related to injury in athletic. PURPOSE: The purpose of this investigations was to assess relationships which may exist between performance in landing mechanics and injury rates throughout a women’s NCAA Division II Collegiate Soccer season. METHODS: Twenty-eight women (age 19.7±1.6 yrs, height 1.6±0.5 m, mass 63.4±7.9 kg) were assessed using the Landing Error Scoring System (LESS) test prior to a competitive season. Injury rates, types, and time lost from participation were tracked throughout the season. Injury information was coded and categorized each week in the following: acute vs. chronic; soft vs. hard tissue; upper vs. lower body; specific anatomical location; contact vs. non-contact; week of injury occurrence; practice days missed from injury; and games missed from injury. Association was measured via a Spearman\u27s rank correlation coefficient and a stepwise linear regression was performed for any variables which showed significant correlation to determine predictive relationships which may exist. The LESS test was evaluated independently by multiple raters and inter-rater reliability was high (ICC=0.824, 95% CI upper and lower = 0.917-0.657, p=0.001). Statistical significance was set a priori at p≤0.05. RESULTS: No significant correlations were determined between LESS test performance and injury and the LESS score did not add strength of association to any predictive variables. DISCUSSION: The main finding of this investigation is that performance on the LESS test did not show significant association with injury rates in women’s collegiate soccer players. LESS test performance has previously been suggested to be a valid and reliable clinical assessment tool, and claims have been made regarding its utility as a screening tool for identification of persons who may be at risk for subsequent injury. Landing mechanics may still be a valid predictor of injury risk. However, the results of our investigation do not support the use of the LESS test as a screening tool for injury risk in women’s collegiate soccer athletes

SDSS-IV MANGA: Spatially Resolved Star Formation Main Sequence and LI(N)ER Sequence

We present our study on the spatially resolved H_alpha and M_star relation for 536 star-forming and 424 quiescent galaxies taken from the MaNGA survey. We show that the star formation rate surface density (Sigma_SFR), derived based on the H_alpha emissions, is strongly correlated with the M_star surface density (Sigma_star) on kpc scales for star- forming galaxies and can be directly connected to the global star-forming sequence. This suggests that the global main sequence may be a consequence of a more fundamental relation on small scales. On the other hand, our result suggests that about 20% of quiescent galaxies in our sample still have star formation activities in the outer region with lower SSFR than typical star-forming galaxies. Meanwhile, we also find a tight correlation between Sigma_H_alpha and Sigma_star for LI(N)ER regions, named the resolved "LI(N)ER" sequence, in quiescent galaxies, which is consistent with the scenario that LI(N)ER emissions are primarily powered by the hot, evolved stars as suggested in the literature.Comment: 6 pages, 4 figures. ApJ Letter accepte