759 research outputs found

    Improvement of Information Retrieval Systems

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    Recent advances in modular archetypes and knowledge-based archetypes are never at odds with extreme programming. In this paper, authors disconfirm the development of active networks, demonstrates the typical importance of machine learning. We use collaborative archetypes to demonstrate that operating systems can be made constant-time, linear-time, and relational

    Evaluation and exploration of a social prescribing initiative: study protocol

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    Attention is being given to healthcare initiatives with the potential to save money and improve lives. One example is Social Prescribing (SP), which supports patients whose ill-health is exacerbated by loneliness. While evidence has accumulated attesting to SP’s efficacy, one limitation has been the lack of a theoretical framework, which limits understanding of how tackling loneliness improves health. In our evaluation of an SP pathway, we adopt a 'Social Cure' approach, which posits that social relations affect health. Our study will evaluate the efficacy of the pathway and determine the extent to which group processes are responsible for health improvements

    Web-based alcohol screening and brief intervention for university students: a randomized trial.

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    IMPORTANCE: Unhealthy alcohol use is a leading contributor to the global burden of disease, particularly among young people. Systematic reviews suggest efficacy of web-based alcohol screening and brief intervention and call for effectiveness trials in settings where it could be sustainably delivered. OBJECTIVE: To evaluate a national web-based alcohol screening and brief intervention program. DESIGN, SETTING, AND PARTICIPANTS: A multisite, double-blind, parallel-group, individually randomized trial was conducted at 7 New Zealand universities. In April and May of 2010, invitations containing hyperlinks to the Alcohol Use Disorders Identification Test-Consumption (AUDIT-C) screening test were e-mailed to 14,991 students aged 17 to 24 years. INTERVENTIONS: Participants who screened positive (AUDIT-C score ≥4) were randomized to undergo screening alone or to 10 minutes of assessment and feedback (including comparisons with medical guidelines and peer norms) on alcohol expenditure, peak blood alcohol concentration, alcohol dependence, and access to help and information. MAIN OUTCOMES AND MEASURES: A fully automated 5-month follow-up assessment was conducted that measured 6 primary outcomes: consumption per typical occasion, drinking frequency, volume of alcohol consumed, an academic problems score, and whether participants exceeded medical guidelines for acute harm (binge drinking) and chronic harm (heavy drinking). A Bonferroni-corrected significance threshold of .0083 was used to account for the 6 comparisons and a sensitivity analysis was used to assess possible attrition bias. RESULTS: Of 5135 students screened, 3422 scored 4 or greater and were randomized, and 83% were followed up. There was a significant effect on 1 of the 6 prespecified outcomes. Relative to control participants, those who received intervention consumed less alcohol per typical drinking occasion (median 4 drinks [interquartile range {IQR}, 2-8] vs 5 drinks [IQR 2-8]; rate ratio [RR], 0.93 [99.17% CI, 0.86-1.00]; P = .005) but not less often (RR, 0.95 [99.17% CI, 0.88-1.03]; P = .08) or less overall (RR, 0.95 [99.17% CI, 0.81-1.10]; P = .33). Academic problem scores were not lower (RR, 0.91 [99.17% CI, 0.76-1.08]; P = .14) and effects on the risks of binge drinking (odds ratio [OR], 0.84 [99.17% CI, 0.67-1.05]; P = .04) and heavy drinking (OR, 0.77 [99.17% CI, 0.56-1.05]; P = .03) were not significantly significant. In a sensitivity analysis accounting for attrition, the effect on alcohol per typical drinking occasion was no longer statistically significant. CONCLUSIONS AND RELEVANCE: A national web-based alcohol screening and brief intervention program produced no significant reductions in the frequency or overall volume of drinking or academic problems. There remains a possibility of a small reduction in the amount of alcohol consumed per typical drinking occasion. TRIAL REGISTRATION: anzctr.org.au Identifier: ACTRN12610000279022

    Beta-delayed gamma decay of 26P: Possible evidence of a proton halo

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    Background: Measurements of β\beta decay provide important nuclear structure information that can be used to probe isospin asymmetries and inform nuclear astrophysics studies. Purpose: To measure the β\beta-delayed γ\gamma decay of 26^{26}P and compare the results with previous experimental results and shell-model calculations. Method: A 26^{26}P fast beam produced using nuclear fragmentation was implanted into a planar germanium detector. Its β\beta-delayed γ\gamma-ray emission was measured with an array of 16 high-purity germanium detectors. Positrons emitted in the decay were detected in coincidence to reduce the background. Results: The absolute intensities of 26^{26}P β\beta-delayed γ\gamma-rays were determined. A total of six new β\beta-decay branches and 15 new γ\gamma-ray lines have been observed for the first time in 26^{26}P β\beta-decay. A complete β\beta-decay scheme was built for the allowed transitions to bound excited states of 26^{26}Si. ftft values and Gamow-Teller strengths were also determined for these transitions and compared with shell model calculations and the mirror β\beta-decay of 26^{26}Na, revealing significant mirror asymmetries. Conclusions: A very good agreement with theoretical predictions based on the USDB shell model is observed. The significant mirror asymmetry observed for the transition to the first excited state (δ=51(10)%\delta=51(10)\%) may be evidence for a proton halo in 26^{26}P.Comment: 15 pages, 10 figures, 7 table

    Instability Heating of Sympathetically-Cooled Ions in a Linear Paul Trap

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    Sympathetic laser cooling of ions stored within a linear-geometry, radio frequency, electric-quadrupole trap has been investigated using computational and theoretical techniques. The simulation, which allows 5 sample ions to interact with 35 laser-cooled atomic ions, revealed an instability heating mechanism, which can prevent ions below a certain critical mass from being sympathetically cooled. This critical mass can however be varied by changing the trapping field parameters thus allowing ions with a very large range of masses to be sympathetically cooled using a single ion species. A theoretical explanation of this instability heating mechanism is presented which predicts that the cooling-heating boundary in trapping parameter space is a line of constant quq_u (ion trap stability coefficient), a result supported by the computational results. The threshold value of quq_u depends on the masses of the interacting ions. A functional form of this dependence is given

    Web-based alcohol intervention for Māori university students: double-blind, multi-site randomized controlled trial.

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    AIMS: Like many indigenous peoples, New Zealand Māori bear a heavy burden of alcohol-related harm relative to their non-indigenous compatriots, and disparities are greatest among young adults. We tested the effectiveness of web-based alcohol screening and brief intervention (e-SBI) for reducing hazardous drinking among Māori university students. DESIGN: Parallel, double-blind, multi-site, randomized controlled trial. SETTING: Seven of New Zealand's eight universities. PARTICIPANTS: In April 2010, we sent e-mail invitations to all 6697 17-24-year-old Māori students to complete a brief web questionnaire including the Alcohol Use Disorders Identification Test (AUDIT)-C, a screening tool for hazardous and harmful drinking. Those screening positive were computer randomized to: <10 minutes of web-based alcohol assessment and personalized feedback (intervention) or screening alone (control). MEASUREMENTS: We conducted a fully automated 5-month follow-up assessment with observers and participants blinded to study hypotheses, design and intervention delivery. Pre-determined primary outcomes were: (i) frequency of drinking, (ii) amount consumed per typical drinking occasion, (iii) overall volume of alcohol consumed and (iv) academic problems. FINDINGS: Of the participants, 1789 were hazardous or harmful drinkers (AUDIT-C ≥ 4) and were randomized: 850 to control, 939 to intervention. Follow-up assessments were completed by 682 controls (80%) and 733 intervention group members (78%). Relative to controls, participants receiving intervention drank less often [RR = 0.89; 95% confidence interval (CI): 0.82-0.97], less per drinking occasion (RR = 0.92; 95% CI: 0.84-1.00), less overall (RR = 0.78; 95% CI: 0.69-0.89) and had fewer academic problems (RR = 0.81; 95% CI: 0.69-0.95). CONCLUSIONS: Web-based screening and brief intervention reduced hazardous and harmful drinking among non-help-seeking Māori students in a large-scale pragmatic trial. The study has wider implications for behavioural intervention in the important but neglected area of indigenous health

    Production of antihydrogen at reduced magnetic field for anti-atom trapping

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    We have demonstrated production of antihydrogen in a 1,,T solenoidal magnetic field. This field strength is significantly smaller than that used in the first generation experiments ATHENA (3,,T) and ATRAP (5,,T). The motivation for using a smaller magnetic field is to facilitate trapping of antihydrogen atoms in a neutral atom trap surrounding the production region. We report the results of measurements with the ALPHA (Antihydrogen Laser PHysics Apparatus) device, which can capture and cool antiprotons at 3,,T, and then mix the antiprotons with positrons at 1,,T. We infer antihydrogen production from the time structure of antiproton annihilations during mixing, using mixing with heated positrons as the null experiment, as demonstrated in ATHENA. Implications for antihydrogen trapping are discussed
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