34 research outputs found

    Stanje ekosistema za uzgoj pastrmke sa aspekta mikrobiološkog rizika

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    Control of microbiological status of ponds and a fish itself is of great importance while the aim of control is to detect indicators of faecal pollution and to evaluate the potential risk of consumption of contaminated aquacultural products. In this paper we investigated microbiological population of rainbow trout ponds, in trout itself and in sludge. Investigations were performed at the beginning of autumn, end of autumn and at the beginning of winter. Results indicated that microbiological status of the pond ecosystem was mainly satisfactory, although there were some sporadic cases of A.hydrophila on trout skin at the beginning of autumn

    A Cilia-inspired Closed-loop Sensor-actuator Array

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    © 2018, Jilin University. Cilia are finger-like cell-surface organelles that are used by certain varieties of aquatic unicellular organisms for motility, sensing and object manipulation. Initiated by internal generators and external mechanical and chemical stimuli, coordinated undulations of cilia lead to the motion of a fluid surrounding the organism. This motion transports micro-particles towards an oral cavity and provides motile force. Inspired by the emergent properties of cilia possessed by the pond organism P. caudatum, we propose a novel smart surface with closed-loop control using sensor-actuators pairings that can manipulate objects. Each vibrating motor actuator is controlled by a localised microcontroller which utilises proximity sensor information to initiate actuation. The circuit boards are designed to be plug-and-play and are infinitely up-scalable and reconfigurable. The smart surface is capable of moving objects at a speed of 7.2 millimetres per second in forward or reverse direction. Further development of this platform will include more anatomically similar biomimetic cilia and control

    POSSIBILITY OF REPLACEMENT OF SODIUM CHLORIDE BY POTASSIUM CHLORIDE IN COOKED SAUSAGES- SENSORY CHARACTERISTICS AND HEALTH

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    **Original scientific paper, presented at 2 nd International Congress on Animal Husbandry “ Ne

    Early surgical revascularization after acute myocardial infarction

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    Oxidative Stress and Cancer Heterogeneity Orchestrate NRF2 Roles Relevant for Therapy Response

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    Oxidative stress and its end-products, such as 4-hydroxynonenal (HNE), initiate activation of the Nuclear Factor Erythroid 2-Related Factor 2 (NRF2)/KEAP1 signaling pathway that plays a crucial role in the maintenance of cellular redox homeostasis. However, an involvement of 4-HNE and NRF2 in processes associated with the initiation of cancer, its progression, and response to therapy includes numerous, highly complex events. They occur through interactions between cancer and stromal cells. These events are dependent on many cell-type specific features. They start with the extent of NRF2 binding to its cytoplasmic repressor, KEAP1, and extend to the permissiveness of chromatin for transcription of ARE-containing genes that are NRF2 targets. This review will explore epigenetic molecular mechanisms of NRF2 transcription through the specific molecular anatomy of its promoter. It will explain the role of NRF2 in cancer stem cells, with respect to cancer therapy resistance. Additionally, it also discusses NRF2 involvement at the cross-roads of communication between tumor associated inflammatory and stromal cells, which is also an important factor involved in the response to therapy
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