80 research outputs found
Epstein-Barr Virus Coinfection in Cerebrospinal Fluid Is Associated With Increased Mortality in Malawian Adults With Bacterial Meningitis
Mortality from adult bacterial meningitis exceeds 50% in sub-Saharan Africa. We postulated that—particularly in individuals infected with human immunodeficiency virus (HIV)—herpes simplex virus, varicella zoster virus, Epstein-Barr virus (EBV), and cytomegalovirus (CMV) in the cerebrospinal fluid (CSF) contribute to poor outcome. CSF from 149 Malawian adults with bacterial meningitis and 39 controls were analyzed using polymerase chain reaction. EBV was detected in 79 of 149 bacterial meningitis patients. Mortality (54%) was associated with higher CSF EBV load when adjusted for HIV (P = .01). CMV was detected in 11 of 115 HIV-infected patients, 8 of whom died. The mechanisms by which EBV and CMV contribute to poor outcome require further investigation
The equivalence of four extensions of context-free grammars
There is currently considerable interest among computational linguists in grammatical formalisms with highly restricted generative power. This paper concerns the relationship between the class of string languages generated by several such formalisms, namely, combinatory categorial grammars, head grammars, linear indexed grammars, and tree adjoining grammars. Each of these formalisms is known to generate a larger class of languages than context-free grammars. The four formalisms under consideration were developed independently and appear superficially to be quite different from one another. The result presented in this paper is that all four of the formalisms under consideration generate exactly the same class of string languages
Deflection control for reinforced recycled aggregate concrete beams: Experimental database and extension of the fib Model Code 2010 model
Recycled aggregate concrete (RAC) has emerged as a viable solution for
solving some of the environmental problems of concrete production.
However, design guidelines for deflection control of reinforced RAC
members have not yet been proposed. This study presents a
comprehensive analysis of the applicability of the fib Model Code 2010
(MC2010) deflection control model to reinforced RAC beams. Three
databases of long-term studies on natural aggregate concrete (NAC) and
RAC beams were compiled and meta-analyses of deflection predictions
by MC2010 were performed. First, the MC2010 deflection control model
was tested against a large database of long-term tests on NAC beams.
Second, a database of RAC and companion NAC beams was compiled
and initial and long-term deflections were calculated using the MC2010
model. It was shown that deflections of RAC beams are significantly
underestimated relative to NAC beams. Previously proposed
modifications for MC2010 equations for shrinkage strain and creep
coefficient were used, and new modifications for the modulus of elasticity
and empirical coefficient β were proposed. The improved MC2010
deflection control model on RAC beams was shown to have equal
performance to that on companion NAC beams. The proposals presented
in this paper can help engineers to more reliably perform deflection
control of reinforced RAC members.This is the peer-reviewed version of the article:
N. Tošić, S. Marinković, and J. de Brito, ‘Deflection control for reinforced recycled aggregate concrete beams: Experimental database and extension of the fib Model Code 2010 model’, Structural Concrete, vol. 20, no. 6, pp. 2015–2029, 2019 [https://doi.org/10.1002/suco.201900035
Reservoir quality of fluvial sandstone reservoirs in salt-walled mini-basins: an example from the Seagull field, Central Graben, North Sea, UK
A family study of coeliac disease.
Thirteen of 141 cases (9 percent) of overt, biopsy proven coeliac disease had a definitely affected relative. The pattern of inheritance in these families is compatible with an incompletely penetrant autosomal dominant gene. There was a female preponderance in the adults and the sporadic cases, but not in the children or the familial cases. The series included a pair of concordant and probably monozygotic twins. The authors believe that coeliac disease, as defined at present, is a heterogeneous condition
Comparative Tests of Beams and Columns Made of Recycled Aggregate Concrete and Natural Aggregate Concrete
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