Health in my community: Conducting and evaluating photovoice as a tool to promote environmental health and leadership among Latino/a youth

BackgroundThe PhotoVoice method has shown substantial promise for work with youth in metropolitan areas, yet its potential for use with Latino youth from agricultural areas has not been well documented.ObjectivesThis project was designed to teach environmental health to 15 high school youth while building their individual and community capacity for studying and addressing shared environmental concerns. The project also aimed to test the utility of PhotoVoice with Latino agricultural youth.MethodsFifteen members of the Youth Community Council (YCC), part of a 15-year project with farmworker families in Salinas, CA, took part in a 12-week PhotoVoice project. Their pictures captured the assets and strengths of their community related to environmental health, and were then analyzed by participants. A multi-pronged evaluation was conducted.ResultsYCC members identified concerns such as poor access to affordable, healthy foods and lack of safe physical spaces in which to play, as well as assets, including caring adults and organizations, and open spaces in surrounding areas. Participants presented their findings on radio, television, at local community events, and to key policy makers. The youth also developed two action plans, a successful 5K run/walk and a school recycling project, still in progress. Evaluation results included significant changes in such areas as perceived ability to make presentations, leadership, and self-confidence, as well as challenges including transportation, group dynamics, and gaining access to people in power.ConclusionThe PhotoVoice method shows promise for environmental health education and youth development in farmworker communities

Spherical codes, maximal local packing density, and the golden ratio

The densest local packing (DLP) problem in d-dimensional Euclidean space Rd involves the placement of N nonoverlapping spheres of unit diameter near an additional fixed unit-diameter sphere such that the greatest distance from the center of the fixed sphere to the centers of any of the N surrounding spheres is minimized. Solutions to the DLP problem are relevant to the realizability of pair correlation functions for packings of nonoverlapping spheres and might prove useful in improving upon the best known upper bounds on the maximum packing fraction of sphere packings in dimensions greater than three. The optimal spherical code problem in Rd involves the placement of the centers of N nonoverlapping spheres of unit diameter onto the surface of a sphere of radius R such that R is minimized. It is proved that in any dimension, all solutions between unity and the golden ratio to the optimal spherical code problem for N spheres are also solutions to the corresponding DLP problem. It follows that for any packing of nonoverlapping spheres of unit diameter, a spherical region of radius less than or equal to the golden ratio centered on an arbitrary sphere center cannot enclose a number of sphere centers greater than one more than the number that can be placed on the region's surface.Comment: 12 pages, 1 figure. Accepted for publication in the Journal of Mathematical Physic

Interleukin-18 mediates cardiac dysfunction induced by western diet independent of obesity and hyperglycemia in the mouse

Obesity and diabetes are independent risk factors for heart failure and are associated with the consumption of diet rich in saturated fat and sugar, Western diet (WD), known to induce cardiac dysfunction in the mouse through incompletely characterized inflammatory mechanisms. We hypothesized that the detrimental cardiac effects of WD are mediated by interleukin-18 (IL-18), pro-inflammatory cytokine linked to cardiac dysfunction. C57BL/6J wild-type male mice and IL-18 knockout male mice were fed high-saturated fat and high-sugar diet for 8 weeks. We measured food intake, body weight and fasting glycemia. We assessed left ventricular (LV) systolic and diastolic function by Doppler echocardiography and cardiac catheterization. In wild-type mice, WD induced a significant increase in isovolumetric relaxation time, myocardial performance index and left ventricular end-diastolic pressure, reflecting an impairment in diastolic function, paired with a mild reduction in LV ejection fraction. IL-18 KO mice had higher food intake and greater increase in body weight without significant differences in hyperglycemia. Despite displaying greater obesity, IL-18 knockout mice fed with WD for 8 weeks had preserved cardiac diastolic function and higher left ventricular ejection fraction. IL-18 mediates diet-induced cardiac dysfunction, independent of food intake and obesity, thus highlighting a disconnect between the metabolic and cardiac effects of IL-18

Geometric characterization of separability and entanglement in pure Gaussian states by single-mode unitary operations

We present a geometric approach to the characterization of separability and entanglement in pure Gaussian states of an arbitrary number of modes. The analysis is performed adapting to continuous variables a formalism based on single subsystem unitary transformations that has been recently introduced to characterize separability and entanglement in pure states of qubits and qutrits [arXiv:0706.1561]. In analogy with the finite-dimensional case, we demonstrate that the $1 \times M$ bipartite entanglement of a multimode pure Gaussian state can be quantified by the minimum squared Euclidean distance between the state itself and the set of states obtained by transforming it via suitable local symplectic (unitary) operations. This minimum distance, corresponding to a, uniquely determined, extremal local operation, defines a novel entanglement monotone equivalent to the entropy of entanglement, and amenable to direct experimental measurement with linear optical schemes.Comment: 7 pages, 1 figure. Discussion expanded, to appear in PR

Gravitational waves about curved backgrounds: a consistency analysis in de Sitter spacetime

Gravitational waves are considered as metric perturbations about a curved background metric, rather than the flat Minkowski metric since several situations of physical interest can be discussed by this generalization. In this case, when the de Donder gauge is imposed, its preservation under infinitesimal spacetime diffeomorphisms is guaranteed if and only if the associated covector is ruled by a second-order hyperbolic operator which is the classical counterpart of the ghost operator in quantum gravity. In such a wave equation, the Ricci term has opposite sign with respect to the wave equation for Maxwell theory in the Lorenz gauge. We are, nevertheless, able to relate the solutions of the two problems, and the algorithm is applied to the case when the curved background geometry is the de Sitter spacetime. Such vector wave equations are studied in two different ways: i) an integral representation, ii) through a solution by factorization of the hyperbolic equation. The latter method is extended to the wave equation of metric perturbations in the de Sitter spacetime. This approach is a step towards a general discussion of gravitational waves in the de Sitter spacetime and might assume relevance in cosmology in order to study the stochastic background emerging from inflation.Comment: 17 pages. Misprints amended in Eqs. 50, 54, 55, 75, 7

PINK1 homozygous W437X mutation in a patient with apparent dominant transmission of parkinsonism.

We analyzed the PINK1 gene in 58 patients with early-onset Parkinsonism and detected the homozygous mutation W437X in 1 patient. The clinical phenotype was characterized by early onset (22 years of age), good re- sponse to levodopa, early fluctuations and dyskinesias, and psychiatric symptoms. The mother, heterozygote for W437X mutation, was affected by Parkinson’s disease and 3 further relatives were reported affected, according to an autosomal dominant transmission

Measurement of the production of a W boson in association with a charm quark in pp collisions at √s = 7 TeV with the ATLAS detector

The production of a W boson in association with a single charm quark is studied using 4.6 fb−1 of pp collision data at s√ = 7 TeV collected with the ATLAS detector at the Large Hadron Collider. In events in which a W boson decays to an electron or muon, the charm quark is tagged either by its semileptonic decay to a muon or by the presence of a charmed meson. The integrated and differential cross sections as a function of the pseudorapidity of the lepton from the W-boson decay are measured. Results are compared to the predictions of next-to-leading-order QCD calculations obtained from various parton distribution function parameterisations. The ratio of the strange-to-down sea-quark distributions is determined to be 0.96+0.26−0.30 at Q 2 = 1.9 GeV2, which supports the hypothesis of an SU(3)-symmetric composition of the light-quark sea. Additionally, the cross-section ratio σ(W + +c¯¯)/σ(W − + c) is compared to the predictions obtained using parton distribution function parameterisations with different assumptions about the s−s¯¯¯ quark asymmetry