Az N-klórprolin és N-klórpirrolidin képződése és bomlása

Kutatómunkánk során a prolin és a pirrolidin hipoklórosavval lejátszódó redoxireakcióját tanulmányoztuk.BSc/BABiomérnökD

Fiber-enhanced Raman multi-gas spectroscopy: what is the potential of its application to breath analysis?

The ancient Greek physicians were already aware that some diseases could be diagnosed from the characteristic odor of patients’ breath. For example – patients with liver failure present a fish-like smell, and a urine-like scent indicates renal failure [1]. The identification of breath compounds for noninvasive medical diagnosis has drawn increasing interest in recent years. Sniffer dogs were successfully trained for the identification of breath samples from lung cancer patients [2,3]. More than 100 volatile organic compounds (VOCs) have been identified in normal human breath, and efforts were made for better understanding of complex VOCs patterns that appear in exhaled breath during specific physiological and pathophysiological processes [1,4,5]. For unambitious disease diagnosis and better understanding of the biochemical pathways, a thorough identification and quantification of the disease markers is essential. The editorial aims to highlight the potential of fiber-enhanced Raman spectroscopy (FERS) as an innovative technique for fast and painless point-of-care (POC) diagnosis of diseases in exhaled human breath. After a short review of some well-established analytical techniques for breath diagnosis, FERS is introduced as novel tool and discussed on some application examples

Alveolar Bone Resorption Evaluation Around Single-piece Designed Bicortical Implants, Using Immediate Loading Protocol, Based on Orthopantomographs

Background: Inserting dental implants in severely atrophied jawbones is a great challenge for the dental practitioner. There are an increasing number of patients who choose dental implantanchored prosthetic restorations despite compromised bone quality and quantity. There have been numerous attempts in adapting implant design for the atrophic crestal bone. One-piece, needle-type basal implant design is a typical design for these cases. These implants are inserted in the remaining compact bone located in the basal aspect of the jawbones. If high primary stability is achieved, these implants are used for immediate loading protocol. From many points of view, this technique is based on contradictory principles compared to classic implant surgery and loading protocols. The aim of this study was to investigate the long-term success of basal one-piece short-diameter dental implants used for immediate loading protocol

Microbial respiration and natural attenuation of benzene contaminated soils investigated by cavity enhanced Raman multi-gas spectroscopy

Soil and groundwater contamination with benzene can cause serious environmental damage. However, many soil microorganisms are capable to adapt and are known to strongly control the fate of organic contamination. Innovative cavity enhanced Raman multi-gas spectroscopy (CERS) was applied to investigate the short-term response of the soil micro-flora to sudden surface contamination with benzene regarding the temporal variations of gas products and their exchange rates with the adjacent atmosphere. 13C-labeled benzene was spiked on a silty-loamy soil column in order to track and separate the changes in heterotrophic soil respiration – involving 12CO2 and O2 – from the natural attenuation process of benzene degradation to ultimately form 13CO2. The respiratory quotient (RQ) decreased from a value 0.98 to 0.46 directly after the spiking and increased again within 33 hours to a value of 0.72. This coincided with the maximum 13CO2 concentration rate (0.63 μmol m−2 s−1), indicating the highest benzene degradation at 33 hours after the spiking event. The diffusion of benzene in the headspace and the biodegradation into 13CO2 were simultaneously monitored and 12 days after the benzene spiking no measurable degradation was detected anymore. The RQ finally returned to a value of 0.96 demonstrating the reestablished aerobic respiration