Fragments de Mémoire

A publicação consiste na edição musical da obra Fragments de Mémoire, para piano e electrónica, de Jean-Sébastien Béreau. A revisão da partitura foi realizada por Ana Telles

UNE NUIT DE NOEL / la Chorale HALLELUJAH ; sous la Direction de J.S. BEREAU ; Prise de son : André CHARLIN

Comprend : IL EST NE LE DIVIN ENFANT - VA, MONTE LA MONTAGNE - DANS UNE ETABLE OBSCURE - DOUCE NUITBnF-Partenariats, Collection sonore - BelieveContient une table des matière

Symptoms assessment and decision to treat patients with advanced Parkinson’s disease based on wearables data

International audienceBody-worn sensors (BWS) could provide valuable information in the management of Parkinson’s disease and support therapeutic decisions based on objective monitoring. To study this pivotal step and better understand how relevant information is extracted from BWS results and translated into treatment adaptation, eight neurologists examined eight virtual cases composed of basic patient profiles and their BWS monitoring results. Sixty-four interpretations of monitoring results and the subsequent therapeutic decisions were collected. Relationship between interrater agreements in the BWS reading and the severity of symptoms were analyzed via correlation studies. Logistic regression was used to identify associations between the BWS parameters and suggested treatment modifications. Interrater agreements were high and significantly associated with the BWS scores. Summarized BWS scores reflecting bradykinesia, dyskinesia, and tremor predicted the direction of treatment modifications. Our results suggest that monitoring information is robustly linked to treatment adaptation and pave the way to loop systems able to automatically propose treatment modifications from BWS recordings information