31 research outputs found
ΠΠΏΡΡ ΡΡΠΏΠ΅ΡΠ½ΠΎΠ³ΠΎ Π»Π΅ΡΠ΅Π½ΠΈΡ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠ° Ρ ΡΠΈΠ½Π΄ΡΠΎΠΌΠΎΠΌ Π’ΡΡΠΊΠΎ
We report a case of successful treatment of a 15-year-old female patient (body mass index 16) diagnosed with Turcot syndrome (familial adenomatous polyposis of the colon) combined with multiple primary malignant tumors, including anaplastic astrocytoma (received combination therapy in 2007), metachronous cecal cancer (underwent subtotal colectomy and 12 courses of polychemotherapy in 2016β2017), and metachronous stage III pT3N1M0 rectal cancer at 8 cm. The patient underwent laparoscopic low resection with extirpation of the ileosigmoid anastomosis, creation of a reservoir-rectal anastomosis, and preventive ileostomy. The patient had minimal intraoperative blood loss and uneventful postoperative period (with an accelerated rehabilitation protocol). She was discharged from a hospital on day 9. Considering previous treatment episodes and the disease stage, we also included into the treatment regimen adjuvant FOLFOX polychemotherapy in a reduced dose for 6 months. During one-year follow up, there was no evidence of disease progression. Later, the patient underwent ileostomy closure with forming a side-to-side mechanical anastomosis. The patient is fully rehabilitated in term of her social activity.Π ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΎΠΌ Π½Π°Π±Π»ΡΠ΄Π΅Π½ΠΈΠΈ ΠΏΡΠΎΠ΄Π΅ΠΌΠΎΠ½ΡΡΡΠΈΡΠΎΠ²Π°Π½ΠΎ ΡΡΠΏΠ΅ΡΠ½ΠΎΠ΅ Π»Π΅ΡΠ΅Π½ΠΈΠ΅ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΊΠΈ Π. Π² Π²ΠΎΠ·ΡΠ°ΡΡΠ΅ 15 Π»Π΅Ρ (ΠΈΠ½Π΄Π΅ΠΊΡ ΠΌΠ°ΡΡΡ ΡΠ΅Π»Π° β 16), Ρ ΠΊΠΎΡΠΎΡΠΎΠΉ Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΡΠΎΠ²Π°Π½ ΡΠΈΠ½Π΄ΡΠΎΠΌ Π’ΡΡΠΊΠΎ β ΡΠ΅ΠΌΠ΅ΠΉΠ½ΡΠΉ Π°Π΄Π΅Π½ΠΎΠΌΠ°ΡΠΎΠ·Π½ΡΠΉ ΠΏΠΎΠ»ΠΈΠΏΠΎΠ· ΡΠΎΠ»ΡΡΠΎΠΉ ΠΊΠΈΡΠΊΠΈ, ΡΠΎΡΠ΅ΡΠ°ΡΡΠΈΠΉΡΡ Ρ ΠΏΠ΅ΡΠ²ΠΈΡΠ½ΠΎ-ΠΌΠ½ΠΎΠΆΠ΅ΡΡΠ²Π΅Π½Π½ΡΠΌΠΈ Π·Π»ΠΎΠΊΠ°ΡΠ΅ΡΡΠ²Π΅Π½Π½ΡΠΌΠΈ ΠΎΠΏΡΡ
ΠΎΠ»ΡΠΌΠΈ (Π°Π½Π°ΠΏΠ»Π°ΡΡΠΈΡΠ΅ΡΠΊΠ°Ρ Π°ΡΡΡΠΎΡΠΈΡΠΎΠΌΠ° Π³ΠΎΠ»ΠΎΠ²Π½ΠΎΠ³ΠΎ ΠΌΠΎΠ·Π³Π°, ΡΠΎΡΡΠΎΡΠ½ΠΈΠ΅ ΠΏΠΎΡΠ»Π΅ ΠΊΠΎΠΌΠ±ΠΈΠ½ΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠ³ΠΎ Π»Π΅ΡΠ΅Π½ΠΈΡ (2007 Π³.); ΠΌΠ΅ΡΠ°Ρ
ΡΠΎΠ½Π½ΡΠΉ ΡΠ°ΠΊ ΡΠ»Π΅ΠΏΠΎΠΉ ΠΊΠΈΡΠΊΠΈ, ΡT3N1M0, ΡΠΎΡΡΠΎΡΠ½ΠΈΠ΅ ΠΏΠΎΡΠ»Π΅ ΡΡΠ±ΡΠΎΡΠ°Π»ΡΠ½ΠΎΠΉ ΠΊΠΎΠ»ΡΠΊΡΠΎΠΌΠΈΠΈ ΠΈ 12 ΠΊΡΡΡΠΎΠ² ΠΏΠΎΠ»ΠΈΡ
ΠΈΠΌΠΈΠΎΡΠ΅ΡΠ°ΠΏΠΈΠΈ Π² 2016β2017 Π³Π³.; ΠΌΠ΅ΡΠ°Ρ
ΡΠΎΠ½Π½ΡΠΉ ΡΠ°ΠΊ ΠΏΡΡΠΌΠΎΠΉ ΠΊΠΈΡΠΊΠΈ Π½Π° 8 ΡΠΌ, ΡT3N1M0, III ΡΡΠ°Π΄ΠΈΡ). ΠΠΎΠ»ΡΠ½ΠΎΠΉ Π²ΡΠΏΠΎΠ»Π½Π΅Π½ΠΎ Ρ
ΠΈΡΡΡΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ΅ Π²ΠΌΠ΅ΡΠ°ΡΠ΅Π»ΡΡΡΠ²ΠΎ Π² ΠΎΠ±ΡΠ΅ΠΌΠ΅ Π»Π°ΠΏΠ°ΡΠΎΡΠΊΠΎΠΏΠΈΡΠ΅ΡΠΊΠΎΠΉ Π½ΠΈΠ·ΠΊΠΎΠΉ ΡΠ΅Π·Π΅ΠΊΡΠΈΠΈ ΠΏΡΡΠΌΠΎΠΉ ΠΊΠΈΡΠΊΠΈ Ρ ΡΠΊΡΡΠΈΡΠΏΠ°ΡΠΈΠ΅ΠΉ ΠΈΠ»Π΅ΠΎΡΠΈΠ³ΠΌΠΎΠ°Π½Π°ΡΡΠΎΠΌΠΎΠ·Π°, ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ΠΌ ΡΠ΅Π·Π΅ΡΠ²ΡΠ°ΡΠΎ-ΡΠ΅ΠΊΡΠ°Π»ΡΠ½ΠΎΠ³ΠΎ Π°Π½Π°ΡΡΠΎΠΌΠΎΠ·Π°, ΠΏΡΠ΅Π²Π΅Π½ΡΠΈΠ²Π½ΠΎΠΉ ΠΈΠ»Π΅ΠΎΡΡΠΎΠΌΠΈΠ΅ΠΉ. ΠΠ½ΡΡΠ°ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΎΠ½Π½Π°Ρ ΠΊΡΠΎΠ²ΠΎΠΏΠΎΡΠ΅ΡΡ ΠΌΠΈΠ½ΠΈΠΌΠ°Π»ΡΠ½Π°. Π’Π΅ΡΠ΅Π½ΠΈΠ΅ ΠΏΠΎΡΠ»Π΅ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΎΠ½Π½ΠΎΠ³ΠΎ ΠΏΠ΅ΡΠΈΠΎΠ΄Π° Π³Π»Π°Π΄ΠΊΠΎΠ΅, Ρ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ΠΌ ΠΏΡΠΎΡΠΎΠΊΠΎΠ»Π° ΡΡΠΊΠΎΡΠ΅Π½Π½ΠΎΠΉ ΡΠ΅Π°Π±ΠΈΠ»ΠΈΡΠ°ΡΠΈΠΈ. ΠΠ°ΡΠΈΠ΅Π½ΡΠΊΠ° Π²ΡΠΏΠΈΡΠ°Π½Π° Π½Π° 9-Π΅ ΡΡΡΠΊΠΈ. Π‘ ΡΡΠ΅ΡΠΎΠΌ Π°Π½Π°ΠΌΠ½Π΅Π·Π° ΠΈ ΡΡΠ°Π΄ΠΈΠΈ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΡ ΠΏΡΠΎΠ²ΠΎΠ΄ΠΈΠ»Π°ΡΡ Π°Π΄ΡΡΠ²Π°Π½ΡΠ½Π°Ρ ΠΏΠΎΠ»ΠΈΡ
ΠΈΠΌΠΈΠΎΡΠ΅ΡΠ°ΠΏΠΈΡ ΠΏΠΎ ΡΡ
Π΅ΠΌΠ΅ FOLFOX Π² ΡΠ΅Π΄ΡΡΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠΉ Π΄ΠΎΠ·Π΅ Π² ΡΠ΅ΡΠ΅Π½ΠΈΠ΅ 6 ΠΌΠ΅Ρ. ΠΠ° 1 Π³ΠΎΠ΄ Π½Π°Π±Π»ΡΠ΄Π΅Π½ΠΈΡ Π΄Π°Π½Π½ΡΡ
, ΡΠΊΠ°Π·ΡΠ²Π°ΡΡΠΈΡ
Π½Π° ΠΏΡΠΎΠ³ΡΠ΅ΡΡΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ ΠΎΡΠ½ΠΎΠ²Π½ΠΎΠ³ΠΎ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΡ, Π½Π΅ ΠΏΠΎΠ»ΡΡΠ΅Π½ΠΎ. Π Π΄Π°Π»ΡΠ½Π΅ΠΉΡΠ΅ΠΌ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΊΠ΅ Π²ΡΠΏΠΎΠ»Π½Π΅Π½ΠΎ Π·Π°ΠΊΡΡΡΠΈΠ΅ ΠΈΠ»Π΅ΠΎΡΡΠΎΠΌΡ Ρ ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ΠΌ Π°ΠΏΠΏΠ°ΡΠ°ΡΠ½ΠΎΠ³ΠΎ Π°Π½Π°ΡΡΠΎΠΌΠΎΠ·Π° Β«Π±ΠΎΠΊ Π² Π±ΠΎΠΊΒ». ΠΠΎΠ»ΡΠ½Π°Ρ ΠΏΠΎΠ»Π½ΠΎΡΡΡΡ ΡΠ΅Π°Π±ΠΈΠ»ΠΈΡΠΈΡΠΎΠ²Π°Π½Π° Π² ΡΠΎΡΠΈΠ°Π»ΡΠ½ΠΎΠΌ Π°ΡΠΏΠ΅ΠΊΡΠ΅
Atopic dermatitis in children
Infant's skin is very sensitive and susceptible to irritants and allergens. Combined with precipitating factors, genetic predisposition plays the key role. Chronic skin inflammation, or atopic dermatitis, is one of the most common pathologies which hinders and limits every day life of the baby and its parents. In the therapy of atopic dermatitis the focus should be on timely and adequate skin care aimed at reducing irritation, preserving the integrity of the child's skin and preventing complications, thereby improving the quality of life
Successful treatment of a patient with Turcot syndrome
We report a case of successful treatment of a 15-year-old female patient (body mass index 16) diagnosed with Turcot syndrome (familial adenomatous polyposis of the colon) combined with multiple primary malignant tumors, including anaplastic astrocytoma (received combination therapy in 2007), metachronous cecal cancer (underwent subtotal colectomy and 12 courses of polychemotherapy in 2016β2017), and metachronous stage III pT3N1M0 rectal cancer at 8 cm. The patient underwent laparoscopic low resection with extirpation of the ileosigmoid anastomosis, creation of a reservoir-rectal anastomosis, and preventive ileostomy. The patient had minimal intraoperative blood loss and uneventful postoperative period (with an accelerated rehabilitation protocol). She was discharged from a hospital on day 9. Considering previous treatment episodes and the disease stage, we also included into the treatment regimen adjuvant FOLFOX polychemotherapy in a reduced dose for 6 months. During one-year follow up, there was no evidence of disease progression. Later, the patient underwent ileostomy closure with forming a side-to-side mechanical anastomosis. The patient is fully rehabilitated in term of her social activity