8,374 research outputs found
The improved nuclear parton distributions
In this paper we propose an improvement of the EKS nuclear parton
distributions for the small x region of high energy processes, where the
perturbative high parton density effects cannot be disregarded. We analyze the
behavior of the ratios and and verify that at small x
they are strongly modified when compared to the EKS predictions. The
implications of our results for the heavy ion collisions in RHIC and LHC are
discussed.Comment: 16 pages, 2 figure
Modes of Information Flow
Information flow between components of a system takes many forms and is key
to understanding the organization and functioning of large-scale, complex
systems. We demonstrate three modalities of information flow from time series X
to time series Y. Intrinsic information flow exists when the past of X is
individually predictive of the present of Y, independent of Y's past; this is
most commonly considered information flow. Shared information flow exists when
X's past is predictive of Y's present in the same manner as Y's past; this
occurs due to synchronization or common driving, for example. Finally,
synergistic information flow occurs when neither X's nor Y's pasts are
predictive of Y's present on their own, but taken together they are. The two
most broadly-employed information-theoretic methods of quantifying information
flow---time-delayed mutual information and transfer entropy---are both
sensitive to a pair of these modalities: time-delayed mutual information to
both intrinsic and shared flow, and transfer entropy to both intrinsic and
synergistic flow. To quantify each mode individually we introduce our
cryptographic flow ansatz, positing that intrinsic flow is synonymous with
secret key agreement between X and Y. Based on this, we employ an
easily-computed secret-key-agreement bound---intrinsic mutual
information&mdashto quantify the three flow modalities in a variety of systems
including asymmetric flows and financial markets.Comment: 11 pages; 10 figures;
http://csc.ucdavis.edu/~cmg/compmech/pubs/ite.ht
Chiral fermion mass and dispersion relations at finite temperature in the presence of hypermagnetic fields
We study the modifications to the real part of the thermal self-energy for
chiral fermions in the presence of a constant external hypermagnetic field. We
compute the dispersion relation for fermions occupying a given Landau level to
first order in g'^2, g^2 and g_phi^2 and to all orders in g'B, where g' and g
are the U(1)_Y and SU(2)_L couplings of the standard model, respectively, g_phi
is the fermion Yukawa coupling, and B is the hypermagnetic field strength. We
show that in the limit where the temperature is large compared to sqrt{g'B},
left- and right-handed modes acquire finite and different B-dependent masses
due to the chiral nature of their coupling with the external field. Given the
current bounds on the strength of primordial magnetic fields, we argue that the
above is the relevant scenario to study the effects of magnetic fields on the
propagation of fermions prior and during the electroweak phase transition.Comment: 11 pages 4 figures, published versio
Molecular Control of the Amount, Subcellular Location and Activity State of Translation Elongation Factor 2 (eEF-2) in Neurons Experiencing Stress
Eukaryotic elongation factor 2 (eEF-2) is an important regulator of the protein translation machinery wherein it controls the movement of the ribosome along the mRNA. The activity of eEF-2 is regulated by changes in cellular energy status and nutrient availability, and posttranslational modifications such as phosphorylation and mono-ADP-ribosylation. However, the mechanisms regulating protein translation under conditions of cellular stress in neurons are unknown. Here we show that when rat hippocampal neurons experience oxidative stress (lipid peroxidation induced by exposure to cumene hydroperoxide; CH), eEF-2 is hyperphosphorylated and ribosylated resulting in reduced translational activity. The degradation of eEF-2 requires calpain proteolytic activity and is accompanied by accumulation of eEF-2 in the nuclear compartment. The subcellular localization of both native and phosphorylated forms of eEF-2 is influenced by CRM1 and 14.3.3, respectively. In hippocampal neurons p53 interacts with non-phosphorylated (active) eEF-2, but not with its phosphorylated form. The p53 – eEF-2 complexes are present in cytoplasm and nucleus, and their abundance increases when neurons experience oxidative stress. The nuclear localization of active eEF-2 depends upon its interaction with p53, as cells lacking p53 contain less active eEF-2 in the nuclear compartment. Overexpression of eEF-2 in hippocampal neurons results in increased nuclear levels of eEF-2, and decreased cell death following exposure to CH. Our results reveal novel molecular mechanisms controlling the differential subcellular localization and activity state of eEF-2 that may influence the survival status of neurons during periods of elevated oxidative stress.España, Ministerio de Ciencia e Innovación BFU2010-20882.España, Ministerio de Educación, Cultura y Deporte postdoctoral fellowship (EX2009-0918
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