Leukemia autopsies in Japan

For the purpose to know whether the annual increase of leukemia incidence in Japan is due to some leukemogenic factors or due to the increased detection rate, the authors made some statistical survey of autopsy cases in which the diagnosis is reliable and not any type of leukemias escape the detection. The results showed that acute leukemias, which are found mostly in younger age, is actually increasing. In addition, it has been deduced that among the suspected factors the increase in ionizing radiation will be one of the most probable factors for the increase in leukemia incidence</p

Analysis of Acute Transfusion Reactions and Their Occurrence Times

Acute transfusion reactions (ATRs) are significantly relevant to the morbidity and mortality of patients. ATRs are mostly not severe and rarely cause severe conditions, including anaphylactic shock. The aim of this study was to clarify the frequency of ATRs and the time of event occurrence. A total of 18,745 transfusions were administered to 11,718 patients during a 3-year period. Adverse reactions including at least one sign or symptom were collected through a report system in 143 of 2,478 (5.7%) platelet concentrate transfusions, 105 of 6,629 (1.6%) red blood cell component transfusions and 51 of 2,307 (2.2%) fresh frozen plasma transfusions. Allergic signs and symptoms accounted for 70% of all adverse events. Severe signs and symptoms were observed in 7.1% of patients. These events appeared significantly earlier than those of non-severe signs and symptoms (median time 20 min vs 100 min, P < 0.05). For patients who have had repetitive transfusion-associated adverse events, preventive treatments for adverse events should be proactively promoted

A case with difficulty in airway management nevertheless switching from emergency tracheostomy to cricothyrotomy

深頸部膿瘍は時に急速な喉頭浮腫を来たし窒息に至ることもある救急疾患である．深夜に救急外来を受診し手術室にて気道確保中に窒息をきたし，院内コードブルー発動を経て救命し得た深頸部膿瘍の1例を経験したので報告する．症例は60代男性．増悪する咽頭痛，軽度の呼吸苦を主訴に当院へ救急搬送された来院後より次第に呼吸苦が増悪し，甲状軟骨内側の膿瘍および高度の喉頭浮腫を認め，気管切開による気道確保を計画した．術中，窒息が切迫した状態となり迅速に気道を確保するために輪状甲状膜切開に術式を切り替えた．しかし，呼吸苦から体動が多く不穏となりまた体動・出血に伴い窒息に至り，徐々に血中酸素飽和度が低下していった通常の手術続行が不可能となった段階で院内コードブルーを要請し，人員を集め，輪状甲状間膜切開・気道確保に成功した最終的には後遺症なく救命が可能であった

社会体育実習授業に関する調査

The purpose of the this paper is to clarify our students needs to course of internship in sports buiseness. Students responded to questionnaire, which has 20 items. We examined the results. 1 Many studenst want to get information of their enterprises which accept them before their pracuticum. 2 Many students are satisfied with their internship and they recommnded this course for their juniors

社会体育実習授業に関する調査第2報

The purpose of the this paper is to clarify our students needs to internship course in sports buiseness. Students responded to a questionnaire which has 20 items.The following results were obtained. 1Many students want to get information of their enterprises which accept them before their pracuticum. 2 Many students are satisfied with their internship and they recommnded this course for their juniors

インターンシップ学外学習に関する調査 : 第3報

The purpose of this paper is to clarify our student\u27s needs to internship course in sports business. Students responded to questionnaire which has 20 items. The following results were obtained. 1 Many students want to get information of their internship which accepts them before their practicum. 2 Many students are satisfied with their internship and they recommended this course for their juniors

Utility of a simplified ultrasonography scoring system among patients with rheumatoid arthritis: A multicenter cohort study

ABSTRACT: We aimed to evaluate the utility of a simplified ultrasonography (US) scoring system, which is desired in daily clinical practice, among patients with rheumatoid arthritis (RA) receiving biological/targeted synthetic disease-modifying antirheumatic drugs (DMARDs).A total of 289 Japanese patients with RA who were started on tumor necrosis factor inhibitors, abatacept, tocilizumab, or Janus kinase inhibitors between June 2013 and April 2019 at one of the 15 participating rheumatology centers were reviewed. We performed US assessment of articular synovia over 22 joints among bilateral wrist and finger joints, and the 22-joint (22j)-GS and 22-joint (22j)-PD scores were evaluated as an indicator of US activity using the sum of the GS and PD scores, respectively.The top 6 most affected joints included the bilateral wrist and second/third metacarpophalangeal joints. Therefore, 6-joint (6j)-GS and -PD scores were defined as the sum of the GS and PD scores from the 6 synovial sites over the aforementioned 6 joints, respectively. Although the 22j- or 6j-US scores were significantly correlated with DAS28-ESR or -CRP scores, the correlations were weak. Conversely, 6j-US scores were significantly and strongly correlated with 22j-US scores not only at baseline but also after therapy initiation.Using a multicenter cohort data, our results indicated that a simplified US scoring system could be adequately tolerated during any disease course among patients with RA receiving biological/targeted synthetic DMARDs