Lymphomas of the female genital tract in Ibadan

Context: Female genital tract cancers are second only to breast malignancies. Cervical cancer is the commonest while epithelial cancers constitute the major histologic type. Lymphoid neoplasms are extremely rare, with the Burkitt's variety accounting for majority of cases seen in the African female.Objective: This is a review of the obstetric/gynaecological patients seen at the University College Hospital, Ibadan between 1976 and 2005, predating the commencement of a nationwide research into non – Hodgkin's lymphoma funded by the Aboderin Foundation.Study Design: Records of subjects were analysed for their  sociodemographic and clinicopathological characteristics, recruiting only those who satisfy the criteria for diagnosing genital tract lymphomas according to Kosari et al1. Retrievable archival paraffin blocks of subjects were also analysed using immunophenotyping.Results: Fifteen cases were identified within the study period; the highest yearly incidence rate being 3 in 1977. In eighteen of the years studied no cases were seen. Most cases (80.0%) occurred in the ovaries. Eighty percent (12) of patients were 25 years or below and nulliparas and grandmultiparas formed 46.7 and 13.4% respectively. Unilateral orbilateral oophorectomy was the commonest surgical procedure (53.3%) while 20.0% had total abdominal hysterectomy with or without bilateral salpingoophorectomy. Data were unavailable concerning use of adjuvanttherapy and outcome of treatment. Four archival paraffin blocks were available for immunophenotyping using the affordable panel of CD20, CD10 and Bcl – 2 antibodies; all were Burkitt's lymphoma.Conclusion: Female genital lymphomas are very rare, affecting the young and nulliparous. The Burkitt's type is commonest

Clients' reasons for prenatal ultrasonography in Ibadan, South West of Nigeria

<p>Abstract</p> <p>Background</p> <p>Prenatal ultrasonography has remained a universal tool but little is known especially from developing countries on clients' reasons for desiring it. Then aim was to determine the reasons why pregnant women will desire a prenatal ultrasound.</p> <p>Methods</p> <p>It was a cross-sectional survey of consecutive 222 women at 2 different ultrasonography facilities in Ibadan, South-west Nigeria.</p> <p>Results</p> <p>The mean age of the respondents was 30.1 ± 4.5 years. The commonest reason for requesting for prenatal ultrasound scans was to check for fetal viability in 144 women (64.7%) of the respondents, followed by fetal gender determination in 50 women (22.6%. Other reasons were to check for number of fetuses, fetal age and placental location. Factors such as younger age, artisans profession and low level of education significantly influenced the decision to check for fetal viability on bivariate analysis but all were not significant on multivariate analysis. Concerning fetal gender determination, older age, Christianity, occupation and gravidity were significant on bivariate analysis, however, only gravidity and occupation remained significant independent predictor on logistic regression model. Women with less than 3 previous pregnancies were about 4 times more likely to request for fetal sex determination than women with more than 3 previous pregnancies, (OR 3.8 95%CI 1.52 – 9.44). The professionals were 7 times more likely than the artisans to request to find out about their fetal sex, (OR 7.0 95%CI 1.47 – 333.20).</p> <p>Conclusion</p> <p>This study shows that Nigerian pregnant women desired prenatal ultrasonography mostly for fetal viability, followed by fetal gender determination. These preferences were influenced by their biosocial variables.</p

Effectiveness of a structured checklist of risk factors in identifying pregnant women at risk of gestational diabetes mellitus: A cross.sectional study

Background: Gestational diabetes mellitus (GDM) is associated with  increased risk of mortality and morbidity for pregnant women and newborns. Identifying pregnant women with risk factors for GDM based on the clinical suspicion is a popular approach. However, the effectiveness of the use of a structured checklist of risk factors is yet to be evaluated. This study assessed the effectiveness of a structured checklist of risk factors in identifying pregnant women at risk of GDM at the University College Hospital, Ibadan.Materials and Methods: It was a comparative cross.sectional study  implemented in two phases. The first phase (Group A) of the study was a prospective study that involved 530 pregnant women who presented at the booking clinic. A structured checklist containing risk factors was used to identify women at the risk of GDM. The second phase (Group B) was a retrospective study of 530 pregnant women managed 2 years previously who were selected by systematic random technique.Results: The mean age, gestational age at booking, gestational age at delivery and birth weight were 30.2 } 5.2 years, 21 } 10.8 weeks, 38.7 } 2.7 weeks and 3.1 } 0.7 kg respectively. The prevalence of GDM in Group A and B were 4.9% and 1.6% respectively (P &lt; 0.05). There was about three fold increase in identification of women at risk of GDM by use of a checklist.Conclusion: Identification of women at risk of GDM was approximately 3.4 fold higher with the use of checklist of risk factors. Exhaustive clinical  identification with a checklist of risk factors for GDM should be encouraged.Key words: Checklist, gestational diabetes, risk factors, screenin