Pharmacogenomics In Pharmacy Practice: Current Perspectives.

Pharmacogenomics (i.e., the application of genetic information in predicting an individual's response to drug therapy) plays an increasingly important role in drug development and decision-making regarding precision medicine. This has been shown to reduce the risk of adverse events and improve patient health-care outcomes through targeted therapies and dosing. As the field of pharmacogenomics rapidly evolves, the role of pharmacists in the education, implementation, and research applications of pharmacogenomics is becoming increasingly recognized. This paper aims to provide an overview and current perspectives of pharmacogenomics in contemporary clinical pharmacy practice and to discuss the future directions on advancing pharmacogenomics education, application, and research in pharmacy practice

Pharmacy Students’ Informal Use of Facebook and its Perceived Role in Pharmacy Education in Jordan

Objectives: The use of social media, including Facebook, as a tool for learning is becoming increasingly important in health professional education programs including pharmacy. This study aimed to evaluate undergraduate pharmacy students’ informal use and attitudes toward Facebook in professional pharmacy education in Jordan. Methods: This study was a cross-sectional web-based survey using a 38-item questionnaire that was developed through a multi-phase iterative process. The study targeted all professional year pharmacy students, both BSc and PharmD, at Jordan University of Science and Technology (JUST). Results: Seven hundred twenty pharmacy students responded to the survey (response rate 31.3%). The majority of the students (98.8%) had personal accounts on Facebook. Of this, the majority (82.4%) reported that they unofficially used Facebook as a tool for studying or academic purposes beside other social purposes. Overall, the students demonstrated positive attitudes toward the use of Facebook in pharmacy education. About 78.6% of the respondents reported that Facebook contributed to their academic success. Furthermore, a substantial proportion of the students found Facebook well acceptable in teaching and learning environment (55.2%) and believed that pharmacy schools should formally encourage students to use Facebook for academic purposes (54.1%). Conclusion: The findings of this study suggest that pharmacy students in Jordan frequently and highly utilize Facebook as an unofficial tool for communication, teaching and learning. Pharmacy schools should make every effort to create appropriate learning environment within Facebook that could positively impact students’ academic success. Interventions to improve attitudes toward social media e-professionalism should be in place before formally implementing Facebook and other social media platforms within the pharmacy academic environment. Conflict of Interest We declare no conflicts of interest or financial interests that the authors or members of their immediate families have in any product or service discussed in the manuscript, including grants (pending or received), employment, gifts, stock holdings or options, honoraria, consultancies, expert testimony, patents and royalties. Treatment of Human Subjects: IRB review/approval required and obtained   Type: Original Researc

Inappropriate polypharmacy management versus deprescribing: A review on their relationship

Medication burden and polypharmacy are highly prevalent among patients with multimorbidity. There have been multiple initiatives to overcome polypharmacy and medication burden in patients with multimorbidity. These initiatives have evolved over time as effective in reducing the negative health consequences of polypharmacy. In recent years, the concept and practice of deprescribing has emerged and gained popularity as an efficient comprehensive approach to manage polypharmacy and ultimately improve health outcomes. Clinicians and researchers with interest in deprescribing view it as a novel and unique strategy that should be a part of effective prescribing process. However, other traditional polypharmacy management strategies such as drug review and medication therapy management still coexist. It is intriguing if deprescribing is considered as a type of these strategies or not. This narrative mini-review explored published literature in an effort to ascertain the differences and similarities between deprescribing and other prominent polypharmacy management interventions. It is clear that there is an overlap between deprescribing and inappropriate polypharmacy management. This is represented by focusing on multimorbid older adults, using similar explicit and implicit tools and having drug review as the core principle of both approaches. This overlap has probably made deprescribing considered as one of polypharmacy management approaches.Scopu

Hospital pharmacists’ self-evaluation of their competence and confidence in conducting pharmacy practice research

Objectives: Research is essential to the advancement of pharmacy practice and healthcare. Pharmacists have a pivotal role to play in this strategy. However, there is a paucity of data about hospital pharmacists’ competence and ability in conducting health-related research. This study primarily aims to determine the research demographics of hospital pharmacists in Qatar and to assess the pharmacists’ perceptions of their competence and confidence to conduct research.Methods: A multi-centered survey using a 70-item piloted questionnaire was conducted among a randomly selected sample of pharmacists practicing at seven Hamad Medical Corporation-managed hospitals. Both descriptive and inferential statistical analyses were applied using IBM-SPSS® version 20.Key findings: A total of 120 participants responded to the survey (67% response rate). About 70% of the participants did not have any previous research experience. At least 20% of the respondents self-reported inadequate competence and/or confidence in developing research protocols, critically appraising the literature, undertaking and applying appropriate statistical techniques, and interpreting research findings. The level of education along with the current hospital of practice had significant effects on pharmacists’ self-assessed competence (p<0.05). Overall, 85% of the participants were interested in pursuing postgraduate studies or research-related training.Conclusions: A large proportion of hospital pharmacists in Qatar self-assessed themselves as having deficiencies in several domains of research process or competencies, although they recognized the value of research in advancing pharmacy practice. These findings have important implications for developing informal research training programs and promoting the pursuit of formal postgraduate programs to bridge the knowledge gaps found among hospital-practicing pharmacists.Open Access funded by King Saud Universit

Structured Multi-Skill Assessment (SMSA) in pharmacy: A contextual adaptation for authentic assessment for colleges of pharmacy and beyond

There is a need for a contextual adaptation model of the Objective Structured Clinical Examination (OSCE) procedures and assessment methods into diverse contexts with great cultural diversity that is both affordable and achievable. This manuscript aims to describe the principles, organizational structure and theoretical framework of the Structured Multi-Skill Assessment (SMSA), a modified version of the OSCE and a performance-based assessment method developed at the Qatar University College of Pharmacy (QU CPH) that addresses contextual and cultural considerations when used in undergraduate pharmacy curricula

Knowledge and Perceptions of Pharmacy Students in Qatar on Anti-Doping in Sports and on Sports Pharmacy in Undergraduate Curricula

Objective. To assess pharmacy students’ knowledge and perceptions of doping and anti-doping in sports and to explore the curricular needs for undergraduate pharmacy in the field of sports pharmacy. Methods. A cross-sectional, descriptive, web-based survey of pharmacy students was conducted at Qatar University College of Pharmacy from March to May 2014. Data were analyzed using descriptive and inferential statistics. Results. Eighty respondents completed the online survey (80% response rate). Sixty percent were unaware of the World Anti-Doping Agency, and 85% were unaware of the International Pharmaceutical Federation’s statement on the pharmacist’s role in anti-doping. Students’ knowledge score regarding the prohibited status of drugs that may be used by athletes was around 50%. Fourth-year pharmacy students had significantly higher knowledge scores than the other groups of students. Respondents acknowledged the important role of health care professionals, including pharmacists, as advisors on the safe and effective use of drugs in sports. Ninety percent of the students supported the inclusion of sports pharmacy in the curriculum. Conclusion. Pharmacy students indicated a strong desire to play a role in doping prevention and ensure safe and rational use of drugs among athletes. They suggested requiring an education and training strategy for sports pharmacy in undergraduate pharmacy curricula.Qatar University Undergraduate Student Research Grant

Determinant factors of resource conflict between farmers and herdsmen in benue state, nigeria.

The determinant factors of resource conflict between farmers and herdsmen in Benue State were analysed. Objectives were to assess the prevalence of resource conflict factors in Benue state and determine factors most responsible for the resource conflict in Benue state. Field survey of three hundred and eighty-two (382) residents was conducted using questionnaire, interview and focus group discussion. Data collected were analyzed using percentage and Factor Analysis. Results showed that factors such as drought, flood, erosion, pollution, politics, greed, proliferation of arms, religion, tribalism, expansion of farmland, increases in herds, poverty, unemployment, cattle rustling, destruction of crops by herds, population growth and urbanization are responsible for the conflict. However, further, analysis of result shows that only 1.38% of respondents posited that environmental/climatic factors, 30% economic factors, 32.78% greed/insecurity, 13.75% and 22.08% posited cultural and population factors respectively. It was concluded that human factors such as economic, greed/insecurity, cultural and population are the major drivers of the resource conflict between farmers and herdsmen than environmental factors like erosion, flood and draught. promote skill acquisition and create jobs to engage youths to boast the economy and reduce conflict. &nbsp

Advancing the Visibility, Impact, and Quality Metrics of Value in Health Regional Issues

[No abstract available]Scopu

Determinant factors of resource conflict between farmers and herdsmen in Benue State, Nigeria

The determinant factors of resource conflict between farmers and herdsmen in Benue State were analysed. Objectives were to assess the prevalence of resource conflict factors in Benue state and determine factors most responsible for the resource conflict in Benue state. Field survey of three hundred and eighty-two (382) residents was conducted using questionnaire, interview and focus group discussion. Data collected were analyzed using percentage and Factor Analysis. Results showed that factors such as drought, flood, erosion, pollution, politics, greed, proliferation of arms, religion, tribalism, expansion of farmland, increases in herds, poverty, unemployment, cattle rustling, destruction of crops by herds, population growth and urbanization are responsible for the conflict. However, further, analysis of result shows that only 1.38% of respondents posited that environmental/climatic factors, 30% economic factors, 32.78% greed/insecurity, 13.75% and 22.08% posited cultural and population factors respectively. It was concluded that human factors such as economic, greed/insecurity, cultural and population are the major drivers of the resource conflict between farmers and herdsmen than environmental factors like erosion, flood and draught. promote skill acquisition and create jobs to engage youths to boast the economy and reduce conflict

A Systematic Review of Instruments for the Assessment of Insomnia in Adults.

Self-reported sleep instruments remain the most practical methods for the assessment of insomnia in clinical practice. This systematic review aims to identify, describe and summarize the psychometric properties of questionnaires available for the assessment of insomnia in the adult population. In addition, the review also aimed to identify sleep instruments available in the Arabic language. A systematic literature search was conducted using the following electronic databases: PubMed, EMBASE, ProQuest Central, SCOPUS, and Google Scholar. The quality assessment of the instruments was conducted using two established international criteria. One hundred and seven articles were selected for inclusion, from which 31 instruments were identified and categorized based on the constructs they assess as: (1) screening for insomnia (n=14); (2) measuring the consequences of insomnia (n=8); (3) assessing the cognitive aspects of insomnia (n= 5); and (4) assessing sleep hygiene (n= 4). The review of the psychometric properties showed that the Insomnia Severity Index and the Functional Outcomes of Sleep Questionnaire were the most extensively evaluated instrument. Criterion validity and reliability measures were the most commonly reported properties. Only four of the identified instruments were available in Arabic. Overall, the findings of this study indicate ample availability of sleep instruments. However, psychometric testing for several of the available sleep instruments remains incomplete, particularly responsiveness and interpretability. Our findings suggest that future studies should focus on reporting more psychometric measures to ensure the trustworthiness of these instruments