Immunogenicity and efficacy of the Hoshino strain of mumps (MMR Vaccine) in Iran

Background: Mumps is an infectious and common disease during childhood. The vaccination against some epidemic diseases like mumps has been introduced in national program. This report describes the immunogenicity and efficacy of Hoshino strain of mumps (included in MMR vaccine) in Iran during 2 years. Methods: Three hundred and thirty eight children aged 3-18 years from Shahr-e-Kord, Iran were enrolled. They were tested for mumps IgG using enzyme-linked immunosorbent assay (ELISA). The percent of susceptible mumps IgG negative children was 19.8% (67 subjects), among them, 36 received the MMR vaccination and successfully completed the study. Blood sample was collected by venipuncture at 3, 12, and 24 months after vaccination and serum samples were tested by ELISA for detection of mumps IgM and IgG. Results: The seroconversion rate was 86.1%, 77.7% and 75% at 3, 12, and 24 months after vaccination respectively. Conclusion: Although the early serocoversion rate was high, but later it declined to a level of 75% which is the same immunity as natural infection which means that the immunity after vaccination would not last for long period of time and there may be a need for introduction of the booster dose of vacc

Immunogenicity and efficacy of Hoshino strain of Mumps Vaccine in Iran; two years study

This report describes the immunogenicity and efficacy and long term  immunity of Hoshino strain of Mumps (included in MMR Vaccine) in shahr-e-kord, Islamic Republic of Iran (I.R.Iran). A total of 338 Children aged 3-18 years were tested for Mumps IgG using enzyme-linked  immunosorbent assay (ELISA). The proportion of susceptible, mumps IgG negative, children was 19.8% (67 subjects). Of the 67 susceptible children, 36 received the MMR vaccination and successfully completed the study. Blood was collected by venipuncture 3, 12, and 24 months after vaccination and serum samples were tested by ELISA for detection of Mumps IgM and IgG. The overall  seroconversion rate was 86.1%, 77.7% and 75% at 3, 12, and 24 months after vaccination respectively.Key Word: Elisa, Hoshino strain, Immunogenicity, Mumps, Vaccine

Healing effect of aloe vera gel, in non-healed ulcers

Objective: Aloe Vera gel (AVG) has a prominent role as a contemporary folk remedy. The Non-healed chronic ulcers of 16 non-responders to conventional treatment were treated with AVG for which the clinical efficacy was studied. Methods: This study included 16 patients having chronic ulcer (9 males and 7 females) with mean age of 41.8±14.6 who following failure treatment to conventional therapy, were dispensed AVG to apply. AVG is consisted from gel part of Aloe Vera plant plus one preservative material, in this study EGG jelly