Spinor Dynamics-Driven Formation of a Dual-Beam Atom Laser

We demonstrate a novel dual-beam atom laser formed by outcoupling oppositely polarized components of an F=1 spinor Bose-Einstein condensate whose Zeeman sublevel populations have been coherently evolved through spin dynamics. The condensate is formed through all-optical means using a single-beam running-wave dipole trap. We create a condensate in the field-insensitive $m_F=0$ state, and drive coherent spin-mixing evolution through adiabatic compression of the initially weak trap. Such dual beams, number-correlated through the angular momentum-conserving reaction $2m_0\leftrightharpoons m_{+1}+m_{-1}$, have been proposed as tools to explore entanglement and squeezing in Bose-Einstein condensates, and have potential use in precision phase measurements.Comment: 4 pages, 4 figure

Time Advancement and Bounds Intersection Checking for Faster Broad-Phase Collision Detection of Paired Object Trajectories

For self-driving mechanisms, the motion planning requires a reasonably fast algorithm for collision detection along the trajectories. We present three algorithms for the detection of collision among objects with predefined trajectories. The first algorithm uses the intersection of the path’s bounding box. The second algorithm sequentially checks for intersection between each pair of corresponding axis-aligned bounding boxes (AABB) from the trajectories of the two paths. Lastly, the latter algorithm is modified using iterative time advancement to an estimated earliest possible collision time. Simulation experiments on a variety of pair trajectories demonstrate a significant speedup of the proposed algorithms over the existing baseline algorithm. They are, therefore, preferable alternatives for faster broad-phase collision detection in applications such as motion planning

KNOWING, CHARACTERIZING AND ASSESSING SYSTEMS OF ORGANIC CROP ROTATIONS

The choice of crop rotations in organic stockless cropping systems is the first leverage used to manage technical issues (to maintain soil fertility, to control pest and weeds) and economic issues (to insure income). The RotAB project (French Casdar funding 2008-2010) implemented complementary approaches to better knowing, characterizing and assessing arable crop rotations. Their conception depends on numerous factors such as the types of soil and climate (on which depend the types of crops, yield potential, possibility of mechanical weed control…) or the economic context (existence of outlets and continuity of markets). If nitrogen supply and weed control are the most important agronomic issues of organic farmers in stockless cropping systems, phosphorus availability appears to be the next important issue for soil fertility and system sustainability

Tea2p is a kinesin-like protein required to generate polarized growth in fission yeast

Cytoplasmic microtubules are critical for establishing and maintaining cell shape and polarity. Our investigations of kinesin-like proteins (klps) and morphological mutants in the fission yeast Schizosaccharomyces pombe have identified a kinesin-like gene, tea2(+), that is required for cells to generate proper polarized growth. Cells deleted for this gene are often bent during exponential growth and initiate growth from improper sites as they exit stationary phase. They have a reduced cytoplasmic microtubule network and display severe morphological defects in genetic backgrounds that produce long cells. The tip-specific marker, Tea1p, is mislocalized in both tea2-1 and tea2Delta cells, indicating that Tea2p function is necessary for proper localization of Tea1p. Tea2p is localized to the tips of the cell and in a punctate pattern within the cell, often coincident with the ends of cytoplasmic microtubules. These results suggest that this kinesin promotes microtubule growth, possibly through interactions with the microtubule end, and that it is important for establishing and maintaining polarized growth along the long axis of the cell

Exploring the limits of ultracold atoms in space

Existing space-based cold atom experiments have demonstrated the utility of microgravity for improvements in observation times and for minimizing the expansion energy and rate of a freely evolving coherent matter wave. In this paper we explore the potential for space-based experiments to extend the limits of ultracold atoms utilizing not just microgravity, but also other aspects of the space environment such as exceptionally good vacuums and extremely cold temperatures. The tantalizing possibility that such experiments may one day be able to probe physics of quantum objects with masses approaching the Planck mass is discussed

Angiogenic markers during preeclampsia: Are they associated with hypertension 1 year postpartum?

Objectives: Preeclampsia is associated with hypertension in later life, but the underlying pathophysiological mechanisms remain uncertain. We aimed to explore whether the angiogenic markers soluble Fms-like tyrosine kinase-1 (sFlt-1) and placental growth factor (PlGF) measured in women with preeclampsia could be associated with hypertension 1 year after delivery. Methods: This is a secondary analysis of a prospective cohort study, originally aimed to evaluate the use of sFlt-1/PlGF ratio to predict adverse outcome in women with (suspected) preeclampsia. Office blood pressure (BP) was evaluated at 1 year postpartum in women who had a confirmed diagnosis of preeclampsia within one week of biomarker measurement. Results: Eighty women were included with a median (interquartile range) gestational age (GA) at biomarker measurement of 30 (27–33) weeks. Twenty-three (29%) women had hypertension 1 year postpartum. These women showed higher median SBP during their pregnancy and lower GA at PE diagnosis compared to women without hypertension. Median PlGF levels were lower in women with hypertension 1 year postpartum compared to women without hypertension (23 vs. 48 pg/mL, p = 0.017), while no differences in sFlt-1 or sFlt-1/PlGF ratio were observed. Multivariable analysis adjusted for GA did not show significant association between PlGF (nor sFlt-1, sFlt-1/PlGF ratio) and hypertension 1 yea

EPIdemiology of Surgery-Associated Acute Kidney Injury (EPIS-AKI) : Study protocol for a multicentre, observational trial

More than 300 million surgical procedures are performed each year. Acute kidney injury (AKI) is a common complication after major surgery and is associated with adverse short-term and long-term outcomes. However, there is a large variation in the incidence of reported AKI rates. The establishment of an accurate epidemiology of surgery-associated AKI is important for healthcare policy, quality initiatives, clinical trials, as well as for improving guidelines. The objective of the Epidemiology of Surgery-associated Acute Kidney Injury (EPIS-AKI) trial is to prospectively evaluate the epidemiology of AKI after major surgery using the latest Kidney Disease: Improving Global Outcomes (KDIGO) consensus definition of AKI. EPIS-AKI is an international prospective, observational, multicentre cohort study including 10 000 patients undergoing major surgery who are subsequently admitted to the ICU or a similar high dependency unit. The primary endpoint is the incidence of AKI within 72 hours after surgery according to the KDIGO criteria. Secondary endpoints include use of renal replacement therapy (RRT), mortality during ICU and hospital stay, length of ICU and hospital stay and major adverse kidney events (combined endpoint consisting of persistent renal dysfunction, RRT and mortality) at day 90. Further, we will evaluate preoperative and intraoperative risk factors affecting the incidence of postoperative AKI. In an add-on analysis, we will assess urinary biomarkers for early detection of AKI. EPIS-AKI has been approved by the leading Ethics Committee of the Medical Council North Rhine-Westphalia, of the Westphalian Wilhelms-University Münster and the corresponding Ethics Committee at each participating site. Results will be disseminated widely and published in peer-reviewed journals, presented at conferences and used to design further AKI-related trials. Trial registration number NCT04165369