568 research outputs found

    Quantum Mechanics

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    Einstein's Local Realism and the Realistic Interpretation of the Wave Function

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    We review the different kinds of realism debates in philosophy and particularly in philosophy of science, then discussing in which ways they may be empirically significant, and analyzing criteria for a (non sharp nor absolute) demarcation between science and philosophy. We then outline two main realistic approaches in the foundations of quantum mechanics, de Broglie’s and Bohm’s “wave existential realism”, and Einstein, Podolski and Rosen’s “properties independence realism”. Both appear quite appealing, but neither has been completely successful. We then draw inspiration from them to propose a complementarity experiment, whereby the reality of quantum waves turns out to be grounded on “non local” properties of quantum systems. In this frame, empirical evidence appears to be relevant both to philosophy and science

    Top-Down Causation by Information Control: From a Philosophical Problem to a Scientific Research Program

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    It has been claimed that different types of causes must be considered in biological systems, including top-down as well as same-level and bottom-up causation, thus enabling the top levels to be causally efficacious in their own right. To clarify this issue, important distinctions between information and signs are introduced here and the concepts of information control and functional equivalence classes in those systems are rigorously defined and used to characterise when top down causation by feedback control happens, in a way that is testable. The causally significant elements we consider are equivalence classes of lower level processes, realised in biological systems through different operations having the same outcome within the context of information control and networks.Comment: Revised version to meet referee's comments, and responding to a paper by Wegscheid et al that was not mentioned in the previous version. 23 pages, 9 figure

    Limit quantum efficiency for violation of Clauser-Horne Inequality for qutrits

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    In this paper we present the results of numerical calculations about the minimal value of detection efficiency for violating the Clauser - Horne inequality for qutrits. Our results show how the use of non-maximally entangled states largely improves this limit respect to maximally entangled ones. A stronger resistance to noise is also found.Comment: Phys. Rev. A in pres

    Visualizing the Quantum Interaction Picture in Phase Space

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    We illustrate the correspondence between the quantum Interaction Picture-evolution of the state of a quantum system in Hilbert space and a combination of local and global transformations of its Wigner function in phase space. To this aim, we consider the time-evolution of a quantized harmonic oscillator driven by both a linear and a quadratic (in terms of bosonic creation and annihilation operators) potentials and employ the Magnus series to derive the exact form of the time-evolution operator. In this case, the Interaction Picture corresponds to a local transformation of phase space-reference frame into the one that is co-moving with the Wigner function.Comment: Submitted to New Journal of Physic

    Damage Detection and Localization on Real Structures Subjected to Strong Motion Earthquakes Using the Curvature Evolution Method: The Navelli (Italy) Case Study

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    In recent years, structural health monitoring (SHM) has received increasing interest from both research and professional engineering communities. This is due to the limitations related to the use of traditional methods based on visual inspection for a rapid and effective assessment of structures and infrastructures when compared with the great potential offered by newly developed automatic systems. Most of these kinds of systems allow the continuous estimation of structural modal properties that are strictly correlated to the mechanical characteristics of the monitored structure. These can change as a result of material deterioration and structural damage related to earthquake shaking. Furthermore, a suitable configuration of a dense sensor network in a real-time monitoring system can allow to detect and localize structural and non-structural damage by comparing the initial and a final state of the structure after a critical event, such as a relevant earthquake. In this paper, the modal curvature evaluation method, used for damage detection and localization on framed structures, considering the mode curvature variation due to strong earthquake shaking, is further developed. The modified approach is validated by numerical and experimental case studies. The extended procedure, named "Curvature Evolution Method" (CEM), reduces the required computing time and the uncertainties in the results. Furthermore, in this work, an empirical relationship between curvature variation and damage index has been defined for both bare and infilled frames

    Metastability of Asymptotically Well-Behaved Potential Games

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    One of the main criticisms to game theory concerns the assumption of full rationality. Logit dynamics is a decentralized algorithm in which a level of irrationality (a.k.a. "noise") is introduced in players' behavior. In this context, the solution concept of interest becomes the logit equilibrium, as opposed to Nash equilibria. Logit equilibria are distributions over strategy profiles that possess several nice properties, including existence and uniqueness. However, there are games in which their computation may take time exponential in the number of players. We therefore look at an approximate version of logit equilibria, called metastable distributions, introduced by Auletta et al. [SODA 2012]. These are distributions that remain stable (i.e., players do not go too far from it) for a super-polynomial number of steps (rather than forever, as for logit equilibria). The hope is that these distributions exist and can be reached quickly by logit dynamics. We identify a class of potential games, called asymptotically well-behaved, for which the behavior of the logit dynamics is not chaotic as the number of players increases so to guarantee meaningful asymptotic results. We prove that any such game admits distributions which are metastable no matter the level of noise present in the system, and the starting profile of the dynamics. These distributions can be quickly reached if the rationality level is not too big when compared to the inverse of the maximum difference in potential. Our proofs build on results which may be of independent interest, including some spectral characterizations of the transition matrix defined by logit dynamics for generic games and the relationship of several convergence measures for Markov chains

    In vitro and in vivo evaluation of 99mTc-polymyxin B for specific targeting of gram-bacteria

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    Background: Infectious diseases are one of the main causes of morbidity and mortality worldwide. Nuclear molecular imaging would be of great help to non-invasively discriminate between septic and sterile inflammation through available radiopharmaceuticals, as none is currently available for clinical practice. Here, we describe the radiolabeling procedure and in vitro and in vivo studies of99mTc-polymyxin B sulfate (PMB) as a new single photon emission imaging agent for the characterization of infections due to Gram-negative bacteria. Results: Labeling efficiency was 97 ± 2% with an average molar activity of 29.5 ± 0.6 MBq/nmol. The product was highly stable in saline and serum up to 6 h. In vitro binding assay showed significant displaceable binding to Gram-negative bacteria but not to Gram-positive controls. In mice,99mTc-HYNIC-PMB was mainly taken up by liver and kidneys. Targeting studies confirmed the specificity of99mTc-HYNIC-PMB obtained in vitro, showing significantly higher T/B ratios for Gram-negative bacteria than Gram-positive controls. Conclusions: In vitro and in vivo results suggest that99mTc-HYNIC-PMB has a potential for in vivo identification of Gram-negative bacteria in patients with infections of unknown etiology. However, further investigations are needed to deeply understand the mechanism of action and behavior of99mTc-HYNIC-PMB in other animal models and in humans
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