Seroprevalence of hepatitis B virus infection among pregnant women attending antenatal clinic in Dalhatu Araf Specialist Hospital, Lafia, Nasarawa State

Context: Hepatitis B virus (HBV) infection is a cause of chronic liver disease, causing cirrhosis and hepatocellular carcinoma, and pregnant women are not spared. Perinatal transmission is a significant way that the disease is spread from mother to children who will eventually become adults and chronic carriers. This study sought to determine the burden of the disease among pregnant women.Aims: To estimate the prevalence and investigate possible factors associated with HBV infection among pregnant women attending antenatal clinics in DASH, Lafia.Settings and Design: A hospital‑based descriptive cross‑sectional survey conducted at the Obstetrics and Gynecology Department of DASH, Lafia, NasarawaMethods and Material: Around 200 pregnant women who attended the ANC clinic were consecutively enrolled, their venous blood samples collected, and hepatitis B profile was carried out using commercially available rapid chromatographic kits Statistical Analysis Used: Data were collected by trained data collectors using a proforma, then entered into a predesigned program in the Epi‑info version 3.5.4 (CDC, Atlanta, Georgia, USA) and analyzed.Results: The seroprevalence of HBV infection was high (8%) and there were no statistically significant associations between the infection and the investigated sociodemographic and other risk factors.Conclusions: The study showed that HBV is hyperendemic in this region, and antenatal screening for this virus is desirable to avert its sequelae in both mothers and their newborn babies. Key words: Antenatal; hepatitis B virus; Lafia

Heavy Metals Accumulation and Phytoremediation Ability of Onion (Allium cepa) and Garlic (Allium sativum) Grown on Contaminated Soils from Challawa Industrial Estate, Kano, Nigeria

This work was designed to assess and compare the heavy metals accumulation and phytoremediation ability of some allium species (Garlic; Allium sativum and Onion; Allium cepa) grown on two different soils (contaminated and Control soils) using standard methods. Heavy metals (of Cr, Fe, Mn, Ni, Pb, and Zn) Concentrations (mg/Kg) were determined using atomic absorption spectrophotometry (AAS Model: 210VGP). Plants growth and biomass production were assessed. Biological concentration factors (BCF) and translocation factors (TF) were calculated. The mean levels of elements obtained ranged widely from 0.55 mg/Kg Ni to 1830.64 mg/Kg Fe. The results showed that onion accumulated higher concentrations of all the heavy metals compared to garlic with exception of Zn. However, the differences in heavy metal concentrations where significant only in Cr and Mn. Phytoremediation efficiency indices (BCF and TF) showed a similar trend for both onion and garlic. The mean BCF values of Pb, Cr, Zn, Mn and Fe in onion were generally high > 1. Ni and Pb had their mean TF values greater than 1. Thus, onion can be used as potential phytoextraction plant. The similarities in most of these metal accumulation trends, BCF and TF between onion and garlic might be due to their being similar species with similar physiological features and from the same family

Outcomes of tuberculosis treatment in a tertiary health facility in north-central Nigeria

Background: Tuberculosis (TB) remains a major public health concern despite being a curable and preventable disease. The treatment of TB using a cocktail of drugs over a period of six months under the directly observed treatment short-course strategy has led to a reduction in cases but is plagued by some challenges that leads to unsuccessful or poor outcomes, which can ultimately result in spread of infections, development of drug resistance and increase in morbidity and mortality. The objectives of this study are to determine outcomes of TB treatment in Dalhatu Araf Specialist Hospital, Lafia, Nasarawa State, Nigeria and the factors that may be associated with the outcomes. Methodology: This was a retrospective study using the medical records of patients who were registered for TB treatment over a five-year period between 2016 to 2020. Data from TB registers including demographic and relevant clinical information, and treatment outcomes, were extracted into a structured data extraction format, and analysed with SPSS version 21.0 software package. Univariate and bivariate analyses were conducted, and Chi square test was used to determine association between TB outcomes and independent variables at 95% confidence interval and p<0.05 was considered as the significant value. Results: Records of 1,313 patients were studied, 744 (56.7%) were males while 569 (43.3%) were females. The age range of the patients was ≤ 1 year - 96 years, with a mean age of 30±16.7 years. Most were pulmonary TB cases (88.8%, n=1,166), newly diagnosed (95.5%, n=1254), and human immunodeficiency virus (HIV) negative at the time of TB diagnosis (63.7%, n=837). Eight hundred and seven (61.5%) patients had successful treatment, and 34% (n=446) had unsuccessful outcomes made of ‘loss to follow-up’ 25.8% (n=339), deaths 7.8% (n=102) and treatment failure 0.4% (n=5), while 2.3% (n=30) were transferred out and 2.3% (n=30) removed from TB register. Treatment success rate was significantly higher in patients with pulmonary TB (p=0.0024), residents in Lafia LGA (p=0.0005), those treated in 2016 (p=0.0006) and bacteriologically confirmed cases (p<0.0001), while death rate was significantly lower among patients who were HIV-negative at the time of TB diagnosis (p<0.0001). Conclusion: TB treatment success rate in this study fell short of the WHO average rate. High rates of ‘loss to followup’ and deaths in this study is a wake-up call to all stakeholders in the facility and the State to put in place measures to reduce poor outcomes of TB treatment

Active tuberculosis among adult HIV-infected patients accessing antiretroviral therapy in a tertiary health facility in Lafia, northcentral Nigeria

Background: Tuberculosis and Human Immunodeficiency Virus (HIV) co-infection is a major problem in Nigeria and other countries that are ravaged by a high burden of both diseases. The World Health Organization (WHO) reports that the risk of developing active tuberculosis (TB) among people living with HIV is 16-27 times that of HIV negative persons. Although antiretroviral therapy (ART) reduces the risk of developing TB, there are factors which predispose those on ART to TB. This study sought to determine the prevalence of TB among adults on ART in our facility and identify the predisposing factors. Methodology: This was a retrospective study utilizing data from clinical records (folders and electronic) of adult HIV patients who are accessing ART in our facility and have been on ART for at least 6 months. A proforma was used to collect data including demographic, clinical, ART and laboratory information of the patients. The data were entered into SPSS version 23 and analyzed using descriptive statistics and bivariate analysis. Associations were tested using Chi square with 95% confidence level. Results: A total of 457 patients were studied, aged 18-69 years (mean age 38.3± 10 years), and 72.4% females. Majority were married (81%), unemployed (53.8%), had mean baseline CD4 cell count of 267.4 ± 185 cells/mm3 and a mean duration on ART of 100.9± 39 months. Seventeen point three percent of the patients had a previous history of TB before or within 6 months of commencement of ART. Thirteen (2.8%) of the patients had active TB while on ART. Majority of those who had active TB were females (76.9%), married (76.9%), unemployed (46%), had no previous history of TB (53.8%), baseline CD4 cell count of ≤ 350 cells/mm3 and were on first line ART medication. There was however no significant statistical association of active TB with any of these factors. Conclusion: Few patients had active TB while on ART in this study. The high frequency of TB in those who had low baseline CD4 cell count and baseline WHO stage shows the importance of early initiation of ART in people living with HIV (PLHIV). There is need for regular screening of PLHIV for TB and innovative approaches to get people with HIV to know their TB status as well as early commencement of ART. Keywords: Human immunodeficiency virus, Active Tuberculosis, Antiretroviral therapy

Tenants' Willingness to Pay for Landscaping Features in Alagbaka Government Reservation Area of Akure, Nigeria

The growing awareness of the contributions of landscaping to real property and the eco-system in general has made real estate industry to integrate landscaping into property decisions. However, little is known about the individual's willingness to pay for the landscape features as consumers do not really have a clear understanding of the landscape value and its connection to property investment. Thus, this study examined the tenants' willingness to pay for landscape features, and the factors that determine their willingness to pay. Data was gotten from ninety three (93) tenants of residential properties within Alagbaka Government Reservation Area (G.R.A) through structured questionnaire. The retrieved data were analyzed using the Frequency Distribution tables to analyze the socio "“ economic characteristics of the respondents, and Binary Logistic Regression Model based on the Contingent Valuation Method to analyze the tenants' willingness to pay for the landscape features and the factors responsible for such choices. The study revealed that tenants are willing to pay bid amount of rent for the incorporation of landscape features into housing process. It further revealed that factors such as Length of stay, Fence and retaining walls, Income, Trees and Shrubs significantly influence tenants' willingness to pay for landscaping. Therefore, the study recommended that landscape be encouraged and properly managed to ensure that it fulfills the full potential of its lifespan and for optimum returns from the properties

Rising trend and indications of caesarean section at the university of Maiduguri teaching hospital, Nigeria

Objective : To determine the trend and indications for the use of caesarean delivery in our environment. Method : A retrospective review of the caesarean sections performed at University of Maiduguri Teaching Hospital from January 2000 to December 2005 inclusive. Results : During the study period, there were 10,097 deliveries and 1192 caesarean sections giving a caesarean section rate of 11.8%. The major maternal indications were cephalopelvic disproportion (15.5%), previous caesarean section (14.7%), eclampsia (7.2%), failed induction of labor (5.5%), and placenta previa (5.1%). Fetal distress (9.6%), breech presentation (4.7%), fetal macrosomia (4.3%), and pregnancy complicated by multiple fetuses (4.2%) were the major fetal indications. The caesarean section rate showed a steady increase over the years (7.20% in 2000-13.95% in 2005), but yearly analysis of the demographic characteristics, type of caesarean section, and the major indications did not reveal any consistent changes to account for the rising trend except for the increasing frequency of fetal distress as an indication of caesarean section over the years, which was also not statistically significant (\u3c7[2] =8.08; P=0.12). The overall perinatal mortality in the study population was found to be 72.7/1000 birth and despite the rising rate of caesarean section, the perinatal outcomes did not improve over the years. Conclusion : Trial of vaginal birth after caesarean section in appropriate cases and use of cardiotocography for continuous fetal heart rate monitoring in labor with confirmation of suspected fetal distress through fetal blood acid--base study are recommended. A prospective study may reveal some of the other reasons for the increasing caesarean section rate

A 5-year review of maternal mortality associated with eclampsia in a tertiary institution in northern Nigeria

Objective : To determine the incidence of maternal mortality associated with eclampsia and to determine how socio-demographic and clinical characteristics of the women influence the deaths. Methodology : Records of 52 eclampsia-related mortalities from January 2003 to December 2007 were reviewed, retrospectively. Their social demography, mode and place of delivery, time of eclampsia, and fetal outcome were extracted for analysis. Results : Eclampsia accounted for 52 (46.4%) of the 112 total maternal deaths recorded within the 5-year period, with case fatality of 22.33%. Age group < 20, 20-29 and above 30 all had similar case fatality rate of 22.1%, 23.8% and 26.7%, respectively. Those who were experiencing their first deliveries have the worst deaths recording 42.5% of the case fatality in that category. As expected, unbooked had higher case fatality of 24.0% compared to 15% among booked cases, while those with no formal education also had more death (22.3% case fatality) as compared to 3.3% among those who had some form of formal education. Antepartum eclampsia was the cause in 50% of the death, 11(21.2%) of the pregnancies were not delivered before their death, while 18 (34.6%) were stillbirth. Conclusion : Eclampsia still remains the major cause of maternal mortality in this region resulting from unsupervised pregnancies and deliveries. There is need to educate and encourage the general public for antenatal care and hospital delivery

Five years Retrospective Study of Avian Coccidiosis in a Veterinary Clinic Bukuru Plateau State Nigeria

This study was conducted to evaluate the incidence of coccidiosis and its association with various risk factors such as age, type of birds and season in a private veterinary clinic in Bukuru, Plateau State Ngeria. A total of 9406 cases during 2013 – 2017 were analysed and 1556 of them were positive for coccidiosis. Several reports on the prevalence of avian coccidiosis have been documented; however, in this study the prevalence of coccidiosis in the study area and its economic consequences was enumerated. Total prevalence of 12.14% in 2013, 18.78% in 2014, 18.21% in 2015, 16.82% in 2016 and 19.07% in 2017 were reported. An overall prevalence of 85.02% was recorded. The average prevalence of coccidiosis based on this five years study is 17%. The association between coccidiosis and age of the birds was determined and age 5-8 weeks becomes most effective period with wet season having high percentage prevalence of coccidiosis. Based on the type of birds, coccidiosis is prevalence almost in equal proportion in both broilers and layers. The losses associated with coccidiosis both direct and indirect components include the cost of control measures, inadequate good hygiene practices, production losses and lack of prophylaxis treatment. The control of coccidiosis is by good sanitary measures by avoiding water spillage, overcrowding, the use of prophylaxis anticoccidials and proper vaccination

Trends in maternal mortality in a tertiary institution in Northern Nigeria

Objective: To look at the trends in maternal mortality in our institution over 5 years. Methods: Records of 112 maternal deaths were retrospectively reviewed to determine the trends and the likely direct cause of each death over the study period. Results: There were a total of 112 maternal deaths, while 3931 deliveries were conducted over the 5-year period. The maternal mortality ratio (MMR) was 2849/100,000 deliveries. The highest MMR of 6234/100,000 was observed in 2003, with remarkable decline to 1837/100,000 in 2007. Eclampsia consistently remained the leading cause, accounting for 46.4% of the maternal deaths, followed by sepsis and postpartum hemorrhage (PPH) contributing 17% and 14.3%, respectively. There were no statistically significant differences in the corresponding percentages of maternal deaths between various age groups (\u3c72=6.68; P =0.083). Grandmultiparas accounted for a significant proportion of maternal deaths as compared to low parity, with \u3c72=10.43; P =0.00054. Lack of seeking antenatal care (unbooked) and illiteracy were observed to be significant determinants of maternal mortality (\u3c72=64.69, P =0.00000; and \u3c72=18.52, P =0.0000168, respectively). Conclusion: In spite of decrease in the maternal mortality ratio over the years, it still remains high, with eclampsia persistently contributing most significantly. Community enlightenment on the need to avail of antenatal care and hospital delivery services, and improvement in the quality of skilled maternity care will, among other factors, drastically curtail these preventable causes of maternal death and reduce MMR