Plain X-ray, computed tomography and magnetic resonance imaging findings of telangiectatic osteosarcoma: a case report

An 18-year-old male patient presented with chronic nonspecific pain of three months located at his left proximal tibia. The patient was admitted to our department for plain X-ray, computed tomography and magnetic resonance imaging examination. Plain X-ray and computed tomography revealed a geographic lytic lesion at the medial aspect of the proximal tibia. Biopsy of the lesion showed telangiectatic osteosarcoma. Image findings of all modalities are presented

The Role of Virtual Cystoscopy, after Multidetector Computed Tomography Imaging Reconstruction without the Use of Contrast Medium, in the Diagnosis and Evaluations of Bladder Tumors: Preliminary Study

Introduction. Although conventional cystoscopy is considered to be the gold standard for diagnosis and follow-up of bladder tumors, it remains an invasive and costly procedure. With the advent of the multidetector CT (MDCT) scanners supported by specialized software virtual cystoscopy (VC) is possible. We assess the role of VC in diagnosing and evaluating bladder lesions. Materials and Methods. Between September 2010 and October 2011, 25 consecutive patients with cystoscopically confirmed bladder tumor underwent VC. The radiologists involved in this prospective study were blinded to the exact findings. After draining any residual urine with a catheter, the bladder was retrogradely insufflated with 200–600 cc of air. No intravenous or intravesical contrast was used. MDCT scan was performed in supine and prone positions and three-dimensional reconstruction of the urinary bladder was performed. Results. The examination was well tolerated by all patients with no complications. In total, 43 lesions were detected both with conventional cystoscopy and VC. Tumor size measured by CT ranged from 3 to 80 mm in diameter. The pathological report revealed noninvasive transitional cell carcinomas in all cases. Conclusion. VC has promising results in detecting exophytic bladder lesions. In the future it could be part of the diagnostic algorithm for bladder tumors

Three-Dimensional Conformal Radiotherapy for Hepatocellular Carcinoma in Patients Unfit for Resection, Ablation, or Chemotherapy: A Retrospective Study

Purpose. The purpose is to evaluate the feasibility, efficacy, and the toxicity of three-dimensional conformal radiotherapy (3DCRT) in patients with advanced hepatocelluar carcinoma (HCC) and inferior vena cava tumor thrombosis (IVCTT). Methods. Between 2007 and 2012, in a retrospective way, 9 patients (median age 69 years) with advanced HCC and IVCTT unfit for surgery, radiofrequency ablation, embolization, or chemotherapy were treated with three-dimensional conformal radiotherapy (3DCRT). The radiotherapy volume included both primary tumor and IVTT. The radiotherapy schedule was 50–52 Gy in 2 Gy fractions. Overall survival (OS), response to radiotherapy, visual analogue scale (VAS), and toxicity were assessed. Results. All patients demonstrated a response rate up to 60%. During radiotherapy, 3 patients experienced grade 1 nausea/vomit toxicity. All patients demonstrated an elevation of the liver enzymes (3 patients with grade 1 and 6 patients with grade 2). The mean VAS-score was decreased from 6.11 to 3.11, while the median overall survival was 24 months. Conclusion. 3DCRT achieves a very high local control rate and is suitable for patients with HCC and IVTT, while the documented radiation induced toxicity is moderate. It can be recommended for palliation in patients unable to undergo curative therapies

DEVELOPMENT OF OUR TECHNIQUE FOR "IN VIVO" MAGNIFICATION ANGIOGRAPHY OF THE KIDNEYS AND THE LIVER.

ΕΙΣ ΤΟ ΑΚΤΙΝΟΛΟΓΙΚΟΝ ΕΡΓΑΣΤΗΡΙΟΝ ΤΟΥ ΠΑΝΕΠΙΣΤΗΜΙΟΥ ΑΘΗΝΩΝ ΑΝΕΠΤΥΧΘΗ ΤΕΧΝΙΚΗ ΑΜΕΣΟΥ ΕΝ ΣΕΙΡΑ ΜΕΓΕΘΥΝΤΙΚΗΣ ΑΓΓΕΙΟΓΡΑΦΙΑΣ ΔΙΑ ΤΗΣ ΧΡΗΣΙΜΟΠΟΙΗΣΕΩΣ ΕΙΔΙΚΗΣ ΠΡΩΤΟΤΥΠΟΥ ΣΥΣΚΕΥΗΣ, ΚΑΤΑΣΚΕΥΑΣΘΕΙΣΗΣ ΕΝ ΕΛΛΑΔΙ, ΤΗ ΥΠΟΔΕΙΞΕΙ ΤΟΥ ΚΑΘΗΓΗΤΟΥ Κ. ΓΡ. ΠΟΝΤΙΦΗΚΟΣ. ΗΚΟΛΟΥΘΗΣΕΝ Η ΠΕΙΡΑΜΑΤΙΚΗ ΚΑΙ ΚΛΙΝΙΚΗ ΕΦΑΡΜΟΓΗ ΤΗΣ ΗΜΕΤΕΡΑΣ ΤΕΧΝΙΚΗΣ. ΤΑ ΑΠΟΤΕΛΕΣΜΑΤΑ ΥΠΗΡΞΑΝ ΛΙΑΝ ΧΡΗΣΙΜΑ ΔΙΑ ΤΗΝ ΕΚΤΙΜΗΣΙΝ ΤΗΣ ΜΟΡΦΟΛΟΓΙΑΣ ΤΟΥΛΕΠΤΟΥ ΑΡΤΗΡΙΑΚΟΥ ΔΙΚΤΥΟΥ ΕΠΙ ΔΙΑΦΟΡΩΝ ΠΑΘΟΛΟΓΙΚΩΝ ΚΑΤΑΣΤΑΣΕΩΝ.AT THE DEPARTMENT OF RADIOLOGY OF THE UNIVERSITY OF ATHENS A TECHNIQUE FOR DIRECT SERIAL MAGNIFICATION ANGIOGRAPHY WAS DEVELOPED BY THE USE OF A SPECIAL APPARATUS, MANUFACTURED IN GREECE UNDER THE INSTRUCTIONS OF PROFESSOR GR. PONTIFEX. THE EXPERIMENTAL AND CLINICAL APPLICATION OF OUR TECHNIQUE FOLLOWED. THE RESULTS HAVE BEEN ESPECIALLY USEFUL IN THE EVALUATION OF SMALL VESSELS IN VARIOUS DISEASE PROCESSES

The efficacy of Caelyx and Hyperthermia for anticancer treatment

The efficacy of Hyperthermia and Caelyx as single modalities of therapy in progressed and refractory cancer of different primary sites is well known. Nevertheless, it remains question mark whether they can work together to that direction. We have recently published a paper which demonstrates some excellent results in treatment of recurrent breast cancer with hyperthermia in conjunction with Caelyx and radiotherapy. The mechanism of action of those different therapeutic options and a review in literature are presented in this paper. Despite the limited number of studies, they all show that the combined treatment is effective and well tolerated. It would be interesting to mention another treatment patent of cancer which can be done by a combination of non-ionizing radiation and androgen deprivation. Also, combined therapy for tumors and tumor metastases comprised administration of integrin ligands and co-therapeutic agents have synergistic efficacy in isolated organ perfusion. Finally, the treatment of solid tumors can be done by glycolytic inhibitors