48 research outputs found
Neural Processing of Emotional Musical and Nonmusical Stimuli in Depression
Background Anterior cingulate cortex (ACC) and striatum are part of the emotional neural circuitry implicated in major depressive disorder (MDD). Music is often used for emotion regulation, and pleasurable music listening activates the dopaminergic system in the brain, including the ACC. The present study uses functional MRI (fMRI) and an emotional nonmusical and musical stimuli paradigm to examine how neural processing of emotionally provocative auditory stimuli is altered within the ACC and striatum in depression.
Method Nineteen MDD and 20 never-depressed (ND) control participants listened to standardized positive and negative emotional musical and nonmusical stimuli during fMRI scanning and gave subjective ratings of valence and arousal following scanning.
Results ND participants exhibited greater activation to positive versus negative stimuli in ventral ACC. When compared with ND participants, MDD participants showed a different pattern of activation in ACC. In the rostral part of the ACC, ND participants showed greater activation for positive information, while MDD participants showed greater activation to negative information. In dorsal ACC, the pattern of activation distinguished between the types of stimuli, with ND participants showing greater activation to music compared to nonmusical stimuli, while MDD participants showed greater activation to nonmusical stimuli, with the greatest response to negative nonmusical stimuli. No group differences were found in striatum.
Conclusions These results suggest that people with depression may process emotional auditory stimuli differently based on both the type of stimulation and the emotional content of that stimulation. This raises the possibility that music may be useful in retraining ACC function, potentially leading to more effective and targeted treatments
1987: Abilene Christian College Bible Lectures - Full Text
THE MIND OF CHRIST
Being the Abilene Christian University Annual Bible Lectures 1987
Published by A.C.U. Press
1634 Campus Court Abilene, Texas 7960
1990: Abilene Christian College Bible Lectures - Full Text
LUKE: A GOSPEL FOR THE WORLD
Being the Abilene Christian University Annual Bible Lectures 1990
Published by ACU PRESS
1634 Campus Court Abilene, Texas 7960
1985: Abilene Christian College Bible Lectures - Full Text
WHAT THE CHURCH NEEDS TO HEAR
Being the Abilene Christian University Annual Bible Lectures 1985
Published by A-C-U PRESS
ACU Station Abilene, Texas 7969
Reigning Over the Lost
Under the general theme of Praying for Reign, this class will promote the idea that our churches need less organizing and more agonizing on our knees. We HAVE not because we ASK not
Lifestyles of the Rich and Amos - Why Rich Religion Gets it Right
Most Christians say they reject health and wealth theology. Most Christians seem to want more than anything to be healthy and wealthy. Amos has something to say to most Christians
Reigning in the Church
Under the general theme of Praying for Reign, this class will promote the idea that our churches need less organizing and more agonizing on our knees. We HAVE not because we ASK not