10 research outputs found

    Breastfeeding Friendly Airport to Support Healthy Tourism

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    Motivation for breastfeeding and social support is very important for the success of exclusive breastfeeding. Breastfeeding support and motivation is obtained from family, leaders and the government. The implication of the government support given is the existence of regulations for organizer of public facilities that stating that the owner of public facilities must support the exclusive breastfeeding program at the airport. The airport is an important means for the mobility of both domestic and foreign tourist. The role of airport is very important to realizing healthy tourism. This study used a case study design. The subjects of this study were the leaders, staff and visitors of Adisutjipto International Airport. The number of informants is five people. The research instruments were interview guides and observation forms. Knowledge, attitudes and informant support for the exclusive breastfeeding program are good. There needs to be a stronger promotion effort for all levels of society so that exclusive breastfeeding programs can be achieved. Provision of nursery rooms at Adisutjipto International Airport is in accordance with government standards with facilities such as tables, chairs, baby boxes, washing stand, dispensers and trash can. Adisutjipto International Airport is confirmed as a breastfeeding friendly airport

    Analysis of Factors That Influence Online Purchasing Decisions in the Millennium

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    This study aims to determine what factors influence the decision of consumers (millennial generation) to make online purchases. The population in this study is the millennial generation born in the 2000s. The research method used is quantitative descriptive using factor analysis techniques. Where the results of the study stated that there are three dominant factors that influence online purchasing decisions, namely lifestyle,easiness, and quality of information

    The Influence of Consumer Reviews Prices and Online on Product Purchase Decisions in Fashion Category in Shopee "(Case Study of Faculty of Economics and Business, University of Muhammadiyah Sumatera Utara)

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    Purchasing decisions are actions taken by consumers to make a product purchase. Many factors influence consumer purchasing decisions, including prices and online consumer reviews. This study aims to determine the effect of price and online consumer reviews on product purchase decisions in the Fashion category in Shopee (Case Study of the Faculty of Economics and Business, University of Muhammadiyah North Sumatra). The population in this study were students of the Faculty of Economics and Business, Muhammadiyah University of North Sumatra (UMSU) with 100 samples of Students of the Faculty of Economics and Business, Muhammadiyah University of North Sumatra (UMSU) who had shop for Fashion products at Shopee in the past 1 year. Data collection techniques use questionnaires or questionnaires that are tested for validity and reliability. The data analysis technique uses multiple regression, classic assumption test, t test, F test and coefficient of determination. Based on the data analysis and discussion in the study, the conclusions are that there is no partial price effect on purchasing decisions with tcount = 1.193 ttable = 1,984. In addition, simultaneously and significantly there is the influence of price and online consumer reviews on product purchasing decisions in the Fashion category in Shopee with the value of Fcount = 47.039> Ftable = 3.09. Determination coefficient value of 0.492 or 49.2% contribution of price and online consumer reviews on product purchase decisions in the Fashion category in Shopee (Case Study of the Faculty of Economics and Business, University of Muhammadiyah North Sumatra) while the remainder is 0.508 or 50.8% influenced by other variables not examined in this study

    Proton-Coupled Electron Transfer

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    Epigenetics in renal cell cancer: mechanisms and clinical applications

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    Renal cell carcinoma (RCC) is characterized by an infrequent number of somatic mutations. By contrast, epigenetic aberrations are commonly found in RCC, indicating that epigenetic reprogramming is an important event in RCC development. Epigenetic alterations comprise several different aberrations, such as changes in histone modifications, DNA methylation, and microRNA levels, and occur in the most important signalling pathways in RCC, such as the von Hippel-Lindau disease tumour suppressor (VHL)-hypoxia-inducible factor (HIF) pathway, the WNT-beta-catenin pathway, and pathways involved in epithelial-mesenchymal transition. Owing to their involvement in these pathways and frequent occurrence in RCC, epigenetic alterations are regarded as potential biomarkers for the early detection of disease and for prediction of prognosis and treatment response. In addition, most of these alterations are potentially reversible, so they also provide new targets for therapy. At the moment, epigenetic biomarkers for RCC are not being used in clinical practice, but targeted epigenetic therapies are under investigation. Understanding the extent of epigenetic changes occurring in RCC and the mechanisms by which they influence disease progression and treatment response, as well as knowledge of current research on biomarkers and treatments, is crucial to successful clinical translation of epigenetics in RCC

    Epigenetics in renal cell cancer: mechanisms and clinical applications

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