Relationship between discordance of lipid parameters and mortality after acute coronary syndrome

European Atherosclerosis So

Discordance of low density lipoprotein cholesterol and non-high density lipoprotein cholesterol and coronary artery disease severity

87th Congress of the European-Atherosclerosis-Society (EAS)European Atherosclerosis So

Evaluation of postural balance in patients with obstructive sleep apnoea syndrome

Introduction. Patients with obstructive sleep apnoea syndrome (OSAS) can be more prone to accidents due to excessive daytime sleepiness which can lead to attention deficits and thereby cause balance problems. One of the tests evaluating postural balance is static posturography (SPG). In this study, we aimed to evaluate postural balance with SPG in OSAS patients.Methods. Patients who were referred to a sleep disorders outpatient clinic of a tertiary health care centre with snoring, daytime sleepiness or witnessed apnoea were enrolled consecutively in this cross-sectional study. They were grouped as the OSAS group and the control group according to the apnoea-hypopnoea index. Posturographic analyses were carried out in all subjects on a SPG platform under five different conditions: eyes open (EO), eyes closed (EC), head rotated to left (HL), head rotated to right (HR), and tandem Romberg.Results. A total of 95 patients and 23 controls were included in the study. In EO conditions, there was no difference between the OSAS group and the control group in any of the posturographic parameters. In EC conditions, change in lateral sway was significantly higher in the OSAS group which also correlated negatively with SaO2(min). HR conditions caused an i ncrease in anterior-posterior (A-P) sway velocity, and HL conditions led to an increase in change in lateral and A-P sways, sway area, and sway area velocity in the OSAS group.Conclusions. Our findings suggest that postural balance in OSAS patients is impaired even in the very first hours of the day, and that the severity of the disease has an impact on postural balance

Nutritional status and severity of coronary artery disease

Objective The aim of this study is to evaluate the association between Nutritional Risk Index (NRI), a simple tool to assess nutritional status, and coronary artery disease severity and complexity in patients undergoing coronary angiography. Methods This study is a retrospective analysis of 822 patients undergoing coronary angiography. Patients with previous revascularization were excluded. Gensini and SYNTAX scores were calculated according to the angiographic images to determine atherosclerosis severity. NRI was calculated as follows: NRI = [15.19 × serum albumin (g/dl)] + [41.7 × (body weight/ideal body weight)]. In patients ≥65 years of age, Geriatric NRI (GNRI) was used instead of NRI. GNRI was calculated as follows: GNRI = [14.89 × serum albumin (g/dl)] + [41.7 × (body weight/ideal body weight)]. Patients were then divided into three groups as previously reported: NRI < 92, NRI 92–98 and NRI > 98. Gensini and SYNTAX scores were compared between three groups. Results The mean age of study population was 61.9 ± 11.1 years. NRI 98 was measured in 212, 321 and 289 patients, respectively. There was no difference regarding to sex, BMI, smoking, hypertension and diabetes mellitus between three groups. Patients with NRI < 92 had the highest mean Gensini score than the patients with NRI 92–98 and NRI > 98 (38.0 ± 40.6 vs. 31.17 ± 42.4 vs. 25.8 ± 38.4, P = 0.005). Also patients with NRI < 92 had the highest mean SYNTAX score than the patients with NRI 92–98 and NRI > 98 (11.8 ± 12.9 vs. 9.3 ± 12.4 vs. 7.7 ± 11.8, P = 0.001). Also, Gensini score of ≥20 and high SYNTAX score of ≥33 were associated with lower NRI (P < 0.001 and P < 0.001, respectively). Conclusion In our study, nutritional status evaluated by the NRI was associated with more extensive and complex coronary atherosclerosis in patients undergoing coronary angiography

The Role of Cardiac Repolarization Index for Sudden Cardiac Death Risk in Patients with Obstructive Sleep Apnea Syndrome without any Systemic Disesae

Introduction: Obstructive sleep apnea syndrome (OSAS) is associated with sudden cardiac death (SCD). In this study we aimed to evaluate the ventricular recovery time in OSAS patients without chronic systemic diseases, such as hypertension, diabetes, thyroid dysfunction, electrolyte imbalance, cardiac disease and the relationship of OSAS with SCD. Materials and Methods: In the study, between January 2008-January 2010, we analyzed 170 patientswith a mean age of 44.45±10.1 (21-75) years, who were clinically suspected of having OSAS. Following overnight polysomnography (PSG), 12 lead surface electrocardiogram (ECG), recordings were perforned and QT minimum, QT maximum and QT dispersion were computed from ECG. Results: The patients were divided into to the following 4 groups; AHI (apnea-hypopnea index) ≤5, 5< AHI ≤15, 15< AHI <30, and AHI ≥30. The mean QTD was 3.8±2 (0.40-9.7) msn in all patients and 3.5±1.8 (0.6-8.9) msn in normal group (AHI ≤5), and 4.5±1.9 (0.4-9.7) msn in severe group (AHI ≥30). It is shown that QTD increases significanty when AHI rises. Discussion: We showed that the patients with OSAS without chronic systemic disorder have higher SCD risks due to increased QT dispersion

Phenological, Pomological and Technological Characteristics of Seedless White Mulberry in Mulberry Genetic Resources of Turkey

This study carried out in 2015 and 2016 to determine phenological, pomological and some technological characteristics of 19 seedless mulberry genotypes of the Malatya Apricot Research Institute. Full-bloom periods of the genotypes varied between 27th of April (Poser 24-07) and 3rd of May (24 MRK 02); start of harvest dates varied between 15th of May (Poser 24-07) and 31st of May (Yediveren 24-08); end of harvest dates varied between 5th of July (Angut 009) and 30th of August (Yediveren 24-08). Fruiting durations varied between 50 days (Angut 009) and 95 days (Gemirgap Dutu 24-05). Of the pomological characteristics, average fruit weights varied between 0.77 g (Angut 009) and 2.46 g (Poser 24-07); water soluble dry matter (WSDM) contents varied between 15.50% (Topu Beyaz 1) and 29.60% (Angut 009). Of the technological characteristics, drying efficiency values varied between 15.79% (44 KE 10) and 39.94% (Angut 009), dry fruit color L values varied between 25.97 (Poser 24-07) and 50.20 (İstanbul Dutu 24-12). Based on present findings, Poser 24-07 genotype was found to be prominent with early fruiting and availability for fresh consumption; Yediveren 24-08 genotype with late fruiting; İstanbul Dutu 24-12 genotype with drying efficiency and Gemirgap Dutu 24-05 and Gemirgap Dutu 24-06 genotypes with their longer fruiting durations. Current findings may be beneficial in mulberry breeding programs

Immunohistochemical localization of leptin and ghrelin in kidney tissue of capsaicin administered diabetic and non-diabetic rats

In this study, we investigated the effect of Capsaicin (CAP) on leptin and ghrelin expression in diabetic kidneys by immunohistochemical method. The subjects were separated into 5 groups: control, sham, diabetes, CAP, and D+CAP. Streptozotocin (45 mg/kg, single dose) was administered to each rat in the diabetes and D+CAP groups intraperitoneally. Rats with blood glucose levels of 200 mg/dL or higher were considered diabetic. Capsaicin (1 mg/kg) was administered subcutaneously to the rats in the CAP and D+CAP groups every day for 2 weeks. H&E, PAS, and Crossman"s Triple staining were performed to examine the histology of the kidney. Leptin and ghrelin in the kidney were examined by immunohistochemical method. Histological examination revealed normal kidney tissue in the control, sham, and CAP groups. The diabetes group showed the glomerulus with scattered and narrowing of the Bowman"s capsule. While leptin immunoreactivity was most intense in the diabetes group, it was observed the weakest in the CAP and D+CAP groups. While strong ghrelin immunoreactivity was seen in the control and sham groups, mild immunoreactivity was seen in the CAP group, and weak immunoreactivity was seen in the diabetes and D+CAP groups. In this study, we concluded that the application of CAP could prevent loss of appetite by reducing the leptin expression during diabetes, but could not protect ghrelin from adverse effects of diabetes

Investigation of antimicrobial activity and morphological properties of metal coated textile surfaces

The results of investigation antimicrobial and surface properties of the textiles metal coated by means of magnetron or the cleaning-deposition system, which is based on sequentially arranged DC anode layer accelerator and hollow cathode, are presented. The antimicrobial properties against bacteria E. coli and S. aureus of cotton and polyester/cotton textiles coated by Cu, Ti and Ag with the use of two different systems were examined and compared.Представлены результаты исследования антимикробных и поверхностных свойств тканей с металлическими напылениями, созданными при помощи магнетрона или чистяще-распылительного устройства на базе последовательно расположенных ускорителя с анодным слоем и полого катода. Определены и сопоставлены антимикробные свойства тканей из хлопка и смеси хлопок/полиэстер с напылениями из Cu, Ti и Ag, созданными с использованием двух этих устройств, против бактерий E. coli и S. aureus.Представлено результати досліджень антимікробних і поверхневих властивостей тканин з металевими напиленнями, створеними за допомогою магнетрона та чистяче-розпилювального пристрою на базі послідовно розташованих прискорювача з анодним шаром та порожнистого катода. Визначені та співставлені антимікробні властивості тканин з бавовни та суміші бавовна/поліестер з напиленнями з Cu, Ti та Ag, створених за допомогою цих пристроїв, проти бактерій E. coli та S. aureus